Chapter 6 : Skeletal System Flashcards

1
Q

Skeletal System

A

Composed of bones, cartilages, and ligaments joined tightly together to form a strong, flexible framework for the body

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2
Q

Skeleton functions

A

Protection, support, movement, electrolyte balance, acid-base balance, blood formation

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3
Q

Osseous tissue

A

Connective tissue with a hardened matrix (deposition of calcium phosphate and other minerals), part of the composition of a bone

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4
Q

Classification of bones

A

Classified based on shape and corresponding function

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5
Q

Four categories for classification of bones

A

Long bones, short bones, irregular bones, flat bones

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6
Q

General features of bones

A

Epiphysis, diaphysis, medullary cavity

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7
Q

Epiphysis

A

Ends of bones, composed of cancellous (spongy) bone

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8
Q

Diaphysis

A

Shaft of bone, composed of compact bone

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9
Q

Medullary cavity

A

Contains yellow bone marrow, epiphyiseal plate

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10
Q

Four main types of bone cells

A

Osteogenic, osteoblasts, osteocytes, osteoclasts (bone is also a composite)

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11
Q

Matrix

A

Composed of inorganic and organic components

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12
Q

Inorganic component

A

Hydroxyapatite (composed mainly of CaPO4 salt)

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13
Q

Organic components

A

Protein and carbohydrate, collagen

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14
Q

Osteogenic (osteoprogenitor) cells

A

Give rise to osteoblasts, osteocytes

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15
Q

Osteoblasts

A

Bone-forming cells, found along endosteum and periosteum, secrete osteocalcin

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16
Q

Osteon (haversian system)

A

Basic structural unit of compact bone

17
Q

Central (haversian) canal

A

Surrounded by concentric lamellae (matrix)

18
Q

Perforating canals

A

Transverse or diagonal passages into the central canal, originate at nutrient foramen?

19
Q

Spongy bone

A

Composed by a network of trabeculae, spaces filled with red marrow, beams arranged to sustain stress

20
Q

Bone development

A

Ossification or osteogenesis (formation of bone)

21
Q

Osteocytes

A

Former osteoblasts that have been trapped in their lacunae, maintain bony matrix, strain sensors

22
Q

Osteoclasts

A

Bone-dissolving cells

23
Q

Bone development (two methods)

A

Intramembranous ossification, endochondral ossification

24
Q

Intramembranous ossification

A

Produces flat bones of skull and clavicles (starts with osteoid and end with diploe)

25
Endochondral ossification
Bone develops from a hyaline model
26
Bone elongation
Involves epiphyseal plates (hyaline cartilage between two transitional zones (metaphysis))
27
Zones of metaphysis
Reverse cartilage, cell proliferation, cell hypertrophy, calcification, bone deposition (spongy bone)
28
Interstitial growth
Result from growth of cartilage within the metaphysis, finite process (epiphyseal lane)
29
Appositional growth
Growth in diameter and thickness (circumferential lamellae)
30
Mineral deposition
Calcium and phosphate are allowed to reach their solubility product (precipitate in the matrix), ectopic ossification (abnormal calcification of soft tissue)
31
Mineral resorption
HC1 secreted by osteoclasts, acid phosphatase (absorbs collagen)
32
Fracture
Break in the bone
33
Two types of fractures
Stress and pathological
34
Granulation tissue
Fibrous mass of capillaries and cells
35
Osteoporosis
Sever loss of bone diversity, osteoclast more active than osteoblasts
36
Osteosarcoma
Most common and deadly form of bone career, metastasizes quickly
37
Remodeling
Wolff's law of bone - the architecture of bone is determined by the mechanical stresses placed up to it, bone adapts to withstand stress
38
Osteogenesis imperfecta
Brittle bones (defect in collagen deposition