Chapter 7 Flashcards
(29 cards)
drugs that slow activity in the CNS
depressants
a chemical group of sedative-hypnotics
barbiturates
drugs used to relax, calm, or tranquilize
sedatives
drugs used to induce sleep
hypnotics
volatile solvents inhaled for intoxicating purposes
inhalants
gamma hydroxybutyrate, chemically related to GABA
GHB
how long a drugs effects last
duration of action
benzodiazepine, date rape drug
rohypnol
drugs used in the treatment of anxiety disorders
anxiolyotics
disorders characterized by uncontrolled movements
epilepsies
drug first introduced in the 1960, reduces anxiety without inducing sleep
benzodiazepines
similar to benzodiazepines but with different chemical structure
nonbenzodiazepines
mechanism of action of benzodiazepines and barbiturates
bind with receptors on GABA receptor complex
mechanism of action of nonbenzodiazepines
selectively target the GABA-A receptors
short acting barbiturates
TOE:15 mins, DOA:2 to 3 hours
intermediate acting barbiturates
TOE:30mins, DOA:5-6 hours
long acting barbiturates
TOE: 1 hour, DOA:6-10 hours
concerns of barbiturates
overdose, abuse and dependence
short term benzodiazepines
2-8 hours, OOE:15-20mins
intermediate acting benzodiazepines
OOE:30 mins, 10-20 hours
long acting benzodiazepines
OOE: 1 hour, 1-3 days
benefits of benzodiazepines
anxiolytics, sleeping agents, anticonvulsants
concerns for benzodiazepines
sedative not appropriate for all anxiety
benefits of non benzodiazepines
anticonvulsants
