Chapter 7: Genetic Linkage Flashcards

1
Q

Chromosomes are made up of

A

DNA

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2
Q

certain units of DNA that influence an organism’s traits are known as …

A

genes

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3
Q

one chromosome has _________ of ______ on it

A

thousands, genes

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4
Q

every cell carries a copy of all your chromosomes (except _________)

A

gametes

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5
Q

genes are inherited via chromosomes passed down through….

A

meiosis

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6
Q

Mendel’s Laws of Segregation & Independent Assortment establish…..

A

a baseline for inheritance

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7
Q

Synteny

A

when 2+ genes are located on the same chromosome

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8
Q

the phenomenon in which genes that are close together on the same chromosome tend to be transmitted as a unit

A

Genetic linkage

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9
Q

What does genetic linkage violate?

A

Medel’s law of segregation

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10
Q

chromosomes can be referred to as a ________ group

A

of linkage groups = # of chromosome types

linkage
# of linkage groups = # of chromosome types

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11
Q

F1 generation was ___________

A

heterozygous

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12
Q

F2 generation showed a ratio of 15.6:1:1.4:4.5 but it should have a ratio of ________

A

9:3:3:1

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13
Q

F2 generation does not __________________

A

follow normal inheritance pattern

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14
Q

Crossing over occurs during meiosis one to

A

create genetic variation

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15
Q

Recombinant

A

combinations of alleles or traits that are not found in the true-breeding paternal generation

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16
Q

nonrecombinant

A

gamete or offspring in which no crossing over has occurred

17
Q

Genetic recombination occurs in what two ways?

A
  1. crossing over
  2. Independent assortment
18
Q

Genetic recombination can occur in __ chromosome but not __ due to ___________________

A

X, Y, size and function of the chromosome

19
Q

The likelihood of crossing over is dependent on

A

distance between two genes on a chromosome

20
Q

how do we know if the resulting genetic variation is due to crossing over or independent assortment?

A

Chi-square analysis

21
Q

Step 1 of Chi-square analysis

A

propose a hypothesis

22
Q

step 2 of Chi-square analysis

A

determine your “expected” values

23
Q

Step 3 of Chi-square analysis

A

compare observed results to the expected results.

24
Q

Null Hypothesis

A

assumes there is no real diff between the observed and expected values

25
Step 4 of Chi-square analysis
calculate for chi-squared
26
Chi-square analysis results determine
the distance *the lower the number the closer together they are
27
genetic mapping method used to determine the _____ _____ and ________ __ ________ of genes that are ______ to each other on the same chromosome
linear order, distance of separation, linked
28
why is genetic mapping useful? in praactice
1. diseases 2. breeding 3. evolution and history
29
genetic mapping relies on
distance
30
genes close together =
less likely to experience crossing over
31
genes far apart =
more likely to experience crossing over
32
if many recombinant offspring are produced the genes must be
farther apart
33
if few recombinant offspring are produced the genes must be
close together
34
why are there nonrecombinants
crossing over occurs in 10% of meiosis Its rare
35
the two recombinant types of offspring can only be produced if crossing over occurred _______ the two linked genes.
between
36
F2 recombinant offspring carry a chromosome that
underwent crossing over
37
Map distance =
(# of recombinant offspring/ total # of offspring) X100
38
The closer to _____% of offspring that are recombinant, the _____ accurate this mapping technique is.
50, less
39
Mitotic recombination
can happen occasionally