Chapter 75-82 Flashcards

1
Q

Lopez VS 20
SQ tacking in cats

A

● 297 cats, 3 treatment groups
o 1. S.c (simple continuous) with tacking (known as quilting), 2. S.c, 3. No SQ closure
o Seroma was less common in s.c with tacking closure group (13%) compared to both s.c (26%) and no closure of SQ (27%)
o There was greater comfort in cats with both s.c closure groups at 1 day PO c.f to no closure group
● Recommendation to close cat subcutis with s.c with tacking for decreased seroma and pain

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2
Q

Travis VS 18
SQ quilting pattern in dogs

A

● 2 groups: quilting group (SQ apposition with tacking) vs nonquilting group (no tacking)
● incisional seroma was lower in quilting group (OR 0.3) compared to nonquilting group
● pain was lower in quilting group
● incidence of SSI not different between studies

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3
Q

Rodriguez VS 18
Biomechanics

A

● post-umbilical region was weakest (compared to preumbilical or umbilical), achieved lowest load to failure
● load to failure was greater in ma compared to females
● no difference seen between full-thickness and fascia-only closure
● tissue failure with suture loosening occurred mainly in 5 x 5 mm suture bite group (compared to 2x2 mm)

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4
Q

Mastrocco VS 21
NPWT and debridement

A

● 3 surgical debridements were required in 2 dogs; 4 surgical debridements were required in 1 dog
● primary closure achieved at 4, 5, and 6 days of NPWT

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5
Q

Cunningham VS 20
lateral extent of SQ bed

A

● 8 cadavers, 4 different size circle defects (2, 4, 6, 8cm); wound bed covered with barium sulphate ->CT
● Extension >2cm from the incision; 2(0/8), 4(1/8), 6(5/8), 8(6/8)
● Extension >3cm form the incision; 2(0/8), 4(0/8), 6(2/8), 8(5/8)
● In larger defects the lateral extent of the SQ wound bed extends past the previously recommended revision margin of 2-3cm, need to consider this for recuts and radiation planning

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6
Q

Salvaggio VS 20
Phovia

A

● Phovia is a novel fluorescence biomodulation product containing two parts;
o 1=blue LED lamp, 2=Carbopol-based hydrogel (topical photo converter)
● Phovia improved re-epithelization, decreased dermal inflammation and improved matrix formation compared to control portions (saline) of the same wound
● No adverse reaction to treatment
● Did not influence macroscopic appearance, but improved microscopic features (above)

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7
Q

Angelou JSAP 20
Elbow hygroma

A

● 4/12 hygromas treated with a drain recurred
● no recurrence was seen in any case treated with primary resection of hygroma

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8
Q

Bates VS 23

A

Perpendicular or diagonal configurations and low-viscosity fluid maximized fluid dispersion and retrieval.
* Wound instillation therapy involves delivering lavage fluid or medications to a closed wound space. This is feasible using a wound-infusion catheter and active suction drain.

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9
Q

Jack JSAP 19
Healing of lower eyelid defects

A

● 3 dogs, 2 dehisced tumor excisions (high grade MCT, melanoma) one laceration
● All healed well without reconstruction, so not all lower eyelid injuries/tumor resections require reconstruction (which is the current notion) and can still have good ophthalmologic outcomes (ie no KKS)

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10
Q

Latimer VS 18
HBOT on wounds

A

● No effects at all. No difference between any of the assessed variables ; contraction, epithelization, subjective wound scores, histopath scores
● Safe (no adverse effects), no evidence to support its use to manage uncomplicated wounds

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11
Q

Nolff VCOT 18
NPWT on wounds

A

● 26 dogs, prospective, randomized clinical study; patients were matched
● Total time to closure was significantly shorter in NPWT (14.2 days) compared with Silver (28.6 days)
● Wound planimetry (measurements) on days 3, 6 and 9 showed significant greater reduction in total wound area for NPWT at all-time points
● Wounds in NPWT group showed less progression of local infection than did wounds in Silver group
● Negative; need for GA at each foam dressing change due to ingrowth of granulation tissue into foam

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12
Q

Heald VS 20
Electroceutical tx

A

● utilized direct current dressings to disinfect tissues in chronic wounds in 1 cat and 1 dog

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13
Q

Repellin VS 21
Manuka honey and essential oil hydrogel

A

● Epithelialization was 10% higher in honey essential oil hydrogel group than control
● wound contraction and histologic score did not differ between groups
● no difference in infection rate among groups (15% infection rate, Staph most common)

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14
Q

Rajeev JAVMA 22
Deep neck infx

A
  • CT was useful to plan for surgery, and surgical treatment resulted in resolution of clinical signs in all dogs with long-term follow-up available.
  • Empirical antimicrobial treatment, such as amoxicillin–clavulanic acid or ampicillin- sulbactam, should be considered.
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15
Q

Tinsely JAVMA 23
ATT with cat bite wounds

A
  • In the multivariable model, age, weight, surgical treatment, ATT and MGCS scores were associated with nonsurvival.
    o For every 1 year of age, odds of nonsurvival increased by 7% (P = .003) and for every 1 kg of body weight, odds of nonsurvival decreased by 14% (P = .005).
    o Odds of dying increased with lower MGCS and higher ATT scores (MGCS: 104% [95% CI, 116% to 267%; P < .001]; ATT: 351% [95% CI, 321% to 632%; P < .001).
    o Odds of dying decreased by 84% (P < .001) in cats that underwent surgery versus those that did not.
  • This multicenter study indicated association of higher ATT and lower MGCS with worse outcome. Older age in- creased the odds of nonsurvival, while each kilogram increase in bodyweight decreased odds of nonsurvival.
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16
Q

Philip JVECC 22
foxtail FB

A
  • The prevalence of foxtail associated disease was 0.25% in dogs and 0.07% in cats over this time period.
    o Most animals were young to middle-aged and presented in the summer months.
  • The most common location in dogs was the aural canal, cutaneous/subcutaneous space, and nasal canal. In cats, ocular fox- tails were most common (30/37).
    o Ultrasound supervised by a boarded radiologist was utilized in 114 cases, mainly for subcutaneous, sublumbar, and intracavitary foxtail locations, with successful location of a foxtail in 72.8% of cases scanned.
    o Computed tomography was performed in 78 dogs with sus- pected intracavitary foxtail migration, and in all cases, structural changes related to the presence of the foxtail were found.
  • Anerobic bacteria were most commonly isolated when a culture was submitted, with Actinomyces spp. rarely isolated.
    o The most common of the 120 anaerobic isolates were Bacteroides/Prevotella spp. (n = 38), Fusobacterium spp. (n = 32), and Peptostreptococcus anaerobius (n = 30).
  • The short-term outcome for foxtail-associated lesions is good, and most cases can be managed on an outpatient basis. A minority of cases develop life-threatening disease and may require a multidisciplinary approach of multimodal imaging, endoscopy, or surgery.
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17
Q

Hennessy VRU 22
hyaxial mm abscess

A
  • Hypaxial muscle abscess is an important differential in dogs presenting for abdominal or back pain, lameness, and nonspecific signs like fever, lethargy, and hyporexia. It can occur concurrently with intrathoracic disease such as pyothorax secondary to migrating vegetal foreign material.
  • Clinical signs included lethargy, fever, increased respiratory effort, and abdominal or back pain.
  • Radiography and/or ultra- sonography were employed during preliminary work up at clinician discretion and respectively revealed changes consistent with osteomyelitis in the cranial lumbar ver- tebrae and heterogenous, hypoechoic areas in the hypaxial musculature consistent with abscesses.
  • Computed tomography findings included enlargement of hypaxial mus- cles with well-defined fluid attenuating noncontrast enhancing areas with a contrast- enhancing rim consistent with abscesses, periosteal reaction and lysis of vertebrae, and retroperitoneal effusion.
  • Computed tomography provided expedient, thorough visualization of the relevant hypaxial lesions for diagnostic and surgical planning purposes and also characterized intrathoracic components of this disease.
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18
Q

De Lorenzi JSAP 18
self inflating tissue expanders

A

● Oxtex self-inflating tissue expanders in cases with distal cutaneous limb defects
○ Hydrogel core and external silicone coating. 3 phases of device expansion;
■ 1. Delay phase 3-4d(no expansion), 2. Control phase of linear expansion, 3. Plateau phase (takes 3-4 weeks to reach)
● Uses “biological creep” = generation of new tissue following a chronic stretching force
● Mean 5 expanders per dog, devices removed after a mean of 24 days
● Primary closure achieved in 8/11 cases
○ All closed when used proximal to elbow/stifle
○ 75% of wounds closed distal to elbow/stifle but proximal to carpus/tarsus
○ 33% closed distal to carpus/tarsus (worst location to do this in) (so don’t use in this location….)
● Major tissue necrosis or vascular compromise occurred in 4/11 cases (kind of a lot!)

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19
Q

Miyazaki VS 18
skin stretchers for sing bilateral mastectomy

A

● Case report, Velcro pads placed, then elastic cables; tightened every 6-8 hrs 2-4 days pre-op
● Both closed without major tension

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20
Q

Massari VS 20
lip to nose flap in cats

A

● SCC excised with 4-5mm margin of normal tissue, tumors were 2-4mm in size
o Invasive SCC in all cases (6 lateral, one dorsal); Complete excision in all cases
● No major complications, all cats had successful flap healing and cosmetic outcomes (per owners)
o 6/7 cats developed self-limiting muzzle oedema
o 3/7 cats had partial thickness necrosis of the flap, spontaneously healed
o No long term complications of chronic rhinitis, sneezing, nasal stenosis

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21
Q

Chiti VS 18
lip to nose in dogs

A

One dog with a dorsal nasal planum defect & one cadaver dog
● Modification to the lip-to lid flap for lower eyelid defects, utilizes the subdermal plexus
o Allows direct mucosal apposition to obtain a good functional and cosmetic outcome
● Successful in the one live patient, good cosmetic outcome

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22
Q

Jones JAVMA 19
Sudermal plexus flaps

A

● Types: advancement (34%), axillary fold (22%), inguinal fold (22%), rotation (17%), transposition (3%), and distant direct (2%)
● Complications noted in 51% of procedures (37% minor, 14% major)
○ Advancement and transposition flaps had the lowest complication rates.
○ Higher complication rate for reconstructing wounds (acute or chronic) compared to tumor excision
○ Most common complication in both dogs and cats was dehiscence of the distal wound edge=30%
○ Mean time to onset of complications was 1 week
● Outcome considered excellent in 48%, good in 36%, fair in 14%, poor in 2%
○ Combined rate of good to excellent outcomes was 84% (so do a SPSF over a more advanced recon sx such as axial pattern flap or free skin graft)

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23
Q

Doyle VCOT 19
superior and inferior labial aa

A

● Angiograms demonstrated that superior and inferior labial arteries were located within the musculomucosal layer of the labia
● At junction of the rostral and caudal half of upper lip, extensive choke anastamoses joined the angiosome of the infraorbital artery
● Inferior labial artery perfused the caudal half of the lower labium and had extensive choke anastomoses with the rostral and middle mental arteries
● superior labial artery and angularis oris artery supply the caudal half of the superior labia, and the infraorbital artery supplies the rostral half of the superior labia

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24
Q

Berns JFMS 20
single pedicle flap for cat stenotic nares

A

● 5 brachycephalic cats with ventral nasal obstruction due to stenotic nares
● skin resected followed by single pedicle advancement flap
● good outcome seen in all 5 cases

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25
Q

Bonventura JAVMA 21
skin grafts on distal aspect of limbs; single vs bilateral procedures

A

● graft outcome deemed successful if viability >75% achieved
● 90% single session procedures were successful
● 82% staged procedures were successful
● graft survival, graft outcome, and complication rate did not differ between groups
● time to complete healing was longer after staged procedures (50 days) vs single-session procedure (30 days)

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26
Q

El Taliawi VS 20
substitiue for PSIS

A

● allogenic fascia lata is biocompatible and can be considered as an alternative to porcine small intestinal submucosa for augmentation in dogs

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27
Q

Crowley JSAP 20
Seed grafts

A

● 15 dogs
● indication for graft: trauma in 12, neoplasia in 3
● complete epithelialization with minimal contracture seen at median 4 weeks after implantation

28
Q

Dunland VS 20
temporal fascia

A
  • A deep, 3 cm wide wound was present between the nose and the frontal sinus. On computed tomographic examination, comminuted open fractures of the frontal and nasal bones were associated with a severe depression of the dorsal wall and presence of bone fragments in the sinus cavities.
  • Bone fragments were apposed with polydioxanone monofilament suture. Bilateral temporal fascia grafts were placed over the bone fragments.
  • The integrity of the frontal and nasal cavities, and the facial profile of the dog were restored. No short-term or long-term complications were observed after 4 months follow up
  • The innovative combination of suture apposition of bone frag- ments and a temporal fascia free graft resulted in very satisfying long-term out- comes in a dog with open sinus and nasal bone fractures.
29
Q

Andries VS 20
cat angiosome in thigh

A

● The dorsal perineal artery had a large cutaneous angiosome on the caudal thigh, which was consistent in most cats
● The ventral perineal artery and cutaneous branch of the popliteal artery had consistent but smaller cutaneous angiosomes

30
Q

Massari JSAP 18
Superficial epigastric flap for single staged preputial recon

A
  • 6 dogs, caudal superficial epigastric flap healed in all dogs, the mucosal graft died in one
  • 50% developed paraphimosis post-op and required revision surgery
31
Q

Proot JSAP 19
Caudal auricular flap

A

● Flap length: width ratio 3:1, all extending to scapular spine
● Optimal wound healing occurred in 31% of dogs and 50% of cats
● Wound dehiscence without flap necrosis occurred in 6% of dogs and 8% of cats
● Wound dehiscence with flap necrosis occurred in 63% of dogs and 42% of cats
● Revision surgery performed in 50% of dogs and 25% of cats

32
Q

Emmerson JSAP 19
Genicular flap

A

● Average flap survival was 99.1%
● 9% developed distal flap necrosis
● Minor complications in 36% (minor wound dehiscence, seroma, infection)
● Major comps requiring revision occurred in 13.6%
● all flaps extended proximally to the level of greater trochanter

33
Q

De la Puerta JSAP 21
Superficial temporal flap

A

● 100% flap survival occurred in 90% of cases
● 40% postoperative complication rate
○ 5% full-thickness partial necrosis of flap; 25% eye-related issues (ectropion, reduced blink)

34
Q

Foster JSAP 22
Cd superficial epigastric flap

A

● In dogs, 67% complication rate (most common complication was dehiscence)
● In cats, 50% complication rate
● Good overall outcome seen in ~75% of cases

35
Q

Villedieu JSAP 22
Superficial brachial flap

A

● postoperative complications occurred in all dogs
○ 44% partial dehiscence
○ 38% partial flap necrosis
○ 31% seroma formation
● 50% of flaps healed with open wound therapy or revision

36
Q

Nakahara VS 20
Angularis oris flap in dogs

A

● reconstruction of defects extending as far rostrally as the maxillary canine tooth were feasible
● surgical success in a short (3) case series

37
Q

Albernaz VS 21
angularis oris flap in cats

A

● flap edema developed in all cases
● angularis oris flap can be used as a reliable option for rostral facial reconstruction

38
Q

Quinlan VS 21
use of indocyanine green for flap visualization

A

● after injection, fluorescence was seen within 15 seconds and remained visible for up to 26 minutes

39
Q

Carroll JSAP 23
mucosal rotating flap for mid maxillary defects

A
  • Dogs underwent maxillectomy for canine acanthomatous ameloblastomas (9), oral squamous cell carcinomas (4), periph- eral odontogenic fibromas (4), oral melanomas (3), oral fibrosarcomas (2), dentigerous cysts (2) and oral osteosarcoma (1) and trauma resulting in an oronasal fistula (1).
  • Twenty-three dogs underwent a single transposition or interpolation flap and three dogs were treated with a double transposition flap.
  • Postoperative complications, including dehiscence or flap necrosis, occurred in six dogs.
  • Random mucosal rotating (transposition or interpolation) flaps are versatile when used to close rostral maxillary defects in dogs. Postoperative complications appear to be more likely when these flaps are used to close mid maxillary defects.
40
Q

Blondel VS 21
imaging techniques for migrating FB

A

● success rate for preop imaging only 60%, improved to 90% with addition of intraoperative ultrasonography
● ultrasound more sensitive (88%) than CT/MRI (57%)

41
Q

de Melo JFMS 21
OVH effect on feline mammary fibroepithelial hyperplasia

A

● mastectomy not performed on any cat
● previous treatment with injectable progestin may result in a more complex clinical presentation of feline fibroepithelial hyperplasia
● ovariohysterectomy is a good treatment option
● treatment with antiprogestin is recommended, especially if persistent mammary growth is detected after OVH

42
Q

Dickerson VS 19
Rostral nasal recon after planectomy

A

● Recon via bilateral labial mucocutaneous rotation flaps
● Complications in 73% (19/26) (9 dogs required revision surgery)
○ Dehiscence in 50% of dogs (gingival incision dehiscence leading to oronasal fistula in 6)
○ Narrowing of nasal orifice in 19%, but none had resp difficulty
● 24/26 SCC, one MCT, one Adenocarcinoma
● MST 1542 days
● Recurrence suspected in 7.7% (2 dogs) both with narrow/incomplete margins
● 10/11 owners interviewed were satisfied with procedure
look at pics

43
Q

Ranganathan VS 21
inter surgeon agreement

A

● prediction interval 6 mm - 95% of surgeons would be expected to deliver a surgical margin between 2.4-3.6 cm

44
Q

Hess JAVMA 18
carboplatin impregnated beads and SQ sarcomas

A

● Overall local disease-free rates 1, 2, and 3 years after surgery were 70%, 70%, and 58%
● Calculated carboplatin content was significantly greater than the labeled amount
● Carboplatin-impregnated beads were well tolerated; however, results of in vitro tests indicated that caution is needed because of manufacturing inconsistencies.

45
Q

Case JAVMA 18
Intralesional triamcinolone administration for mast cell tumors

A

● Response: 67%: 4 with complete/ 12 with partial response- some with prednisone or with chemotherapy.
● Complications: local hemorrhage and GI ulceration
● Median time to progression= 63 days

46
Q

Karbe VS 21
scar revision for MCT

A

● residual MCT found in 27% of resected scars
● 8% of scars had incomplete or narrow margins
● local recurrence reported in 4% of dogs, disease progression in 15%
● margin status and presence of MCT in the resected scar were not associated with local recurrence or disease progression
● disease progression was significantly more likely in grade 3 tumors

47
Q

Iodence JAVMA 22
MCT and incisional comps

A

● complication rates do not differ between excision of MCT and STS group
● for the MCT group, incomplete margins, increasing Patnaik tumor grade, and postoperative chemo were associated with increased odds of incisional complications
● overall complication rate 13%

48
Q

Cockburn JAVMA 22
marginal excision of cutaneous MCT and comps

A

● wound complications in 30% of both MCT and STS group
● use of subdermal plexus flaps was associated with development of complications

49
Q

Chu JAVMA 20
comparison of surgical margins

A

● The conservative-margin approach appeared to be noninferior to the wide- margin approach for achieving tumor-free histologic margins:
o Conservative 93%, wide 92%

50
Q

Milovancev VS 18
reduction in margin length of MCT and STS

A

● Compared to in vivo dimensions, the length of surgical margins at each processing step (ie, ex vivo, postfixation, subgross, and HTFM) was reduced by a median of
o 3.0, 5.0, 6.0, and 8.8 mm for MCT
o 2.5, 2.0, 5.0, and 5.0 mm for STS
● The maximum reduction in the total length of margins (from in vivo to HTFM) was 29.6mm for MCT and 24.2 mm STS

51
Q

Chalfon JSAP 22
lymphadenectomy with MCT

A
  • Median time to progression was significantly shorter in dogs that did not undergo lymphadenectomy compared to the other dogs
  • Median survival time was also shorter in dogs that did not undergo lymphadenectomy compared to dogs that underwent lymphadenectomy
  • Regional lymphadenectomy may improve outcome in dogs with biologically aggressive cutaneous mast cell tumours.
52
Q

Beer JSAP 22
use of near-infrared fluorescent image guided LN dissection

A
  • Using near-infrared fluores- cent image-guided lymph node dissection, we identified at least one metastatic node in 68% of dogs (24 of 35) compared with 33% (14 of 43) when lymph node dissection was used without imaging.
53
Q

Farmer VRU 23
CT features of MCT in dogs

A

CT findings were deemed insufficient for curative surgical planning in 13 of 16 due to inadequate definition of tumor depth, compartment boundary (fascial plane) or MCT margins. The use of CT for presurgical planning of SC/InterM/IntraM MCT dogs has limitations, especially when differentiating MCT from the adjacent muscle

54
Q

Alvarez-Sanchez VS 23
Comparing CT and near-infrared fluorescence to find sentinel LN in MCT

A
  • Technique agreement of at least one SLN was seen in 16/20 (80%) dogs. Although most MCT were classified as intermediate to low grade, LN metastases were commonly detected
55
Q

Cherzan VS 23
SQ MCT

A
  • Lymph node metastasis decreased disease-free interval and survival.
    Subcutaneous mast cell tumors may be a more aggressive disease than previously reported.
56
Q

Gagnon JAVMA 20
RT for STS

A

● overall response rate 46% → 36% partial response, 11% complete response
● median progression free survival 521d
● median overall survival 700d
● low histologic grade and extremity location was positive prognostic for patient survival

57
Q

Crownshaw JAVMA 20
Variable associated with outcomes in incompletely excised STS

A

● median overall survival 980d
● median 1-, 3-, and 5-year survival rates 85%, 43%, 18%
● 24% developed metastasis
● 20% local recurrence rate
● hazard of disease progression increased as mitotic index or duration of radiation therapy increased
● hazard of death increased as RT duration or surgical scar length increased
● no benefit of chemotherapy seen

58
Q

Villedieu JAVMA 21
Pulmonary nodules with STS

A

● 12% metastasis rate at presentation (6% grade I, 6% grade II, and 40% grade III)
● odds of pulmonary mets were higher with grade 3 STS and dogs s with duration of mass > 3 months
● pulmonary staging was low-yield diagnostic procedure for grade 1 and 2 STS

59
Q

Dobromylsky JFMS 21
Prognostics factors for STS in cats

A

● novel grading system showed significant difference in MST with low (900d), intermediate (500d) and high (280d) STS
● gave scores for mitoses, tumor necrosis, and inflammation
● low score < 3, intermediate 4-5, and high score > 6

60
Q

Milovancev VS 20
MCTvs STS recurrence

A

● MCT margins were 2cm, STS 3cm
● narrowest histologic margin was <1 mm in 40% of MCT, 40% of STS
● Local recurrence rates (4%) among predominantly low- to intermediate- grade MCTs were low, despite a high prevalence of histologic tumor-free margins <1 mm
● No local recurrence or mets with any STS case

61
Q

Bloch JFMS 20
FISS and brachytherapy

A

● median time to tumor progression 620d; survival time 1200d
● 1 year survival rate 64%, 2 year survival rate 41%
● local failure rate 55%
● multiple surgeries prior to brachytherapy was a negative prognostic (310d)

62
Q

Price JSAP 23
risk factors for mammary tumors in cats

A
  • incidence risk of 104 per 100,000 during 2016.
    o increasing age, purebred compared to cross- bred and veterinary group were associated with increased odds of mammary tumour.
  • Median survival after the diagnosis of mammary tumour cats was 18.7 months.
  • The current study provides an updated estimate of the incidence of mammary cancer in cats seen in primary care veterinary practice in the UK with increasing risk seen in older cats and with purebred status.
63
Q

Petrucci JFMS 21
metastatic feline mammary cancer

A

● 73 cats with metastatic mammary tumors
● overall survival time 25 days
● cats with clinical signs, pleural effusion had lower survival time than asymptomatic cats

64
Q

Evans JAVMA 21
facts including comps following dog mastectomies

A

● complication rate following mastectomy was 17%
● high body weight, bilateral mastectomy, and postoperative ABX were associated with increased odds of complications
● chain mastectomy that did not receive postoperative ABX  highest odds of complications
● dogs undergoing concurrent spay had significantly decreased odds of complications

65
Q

Gemignani JAVMA 18
cat mammary adernocarcinoma

A

● Complications rates::
○ 20% unilateral mastectomy
○ 35% staged bilateral mastectomy
○ 40% single-session bilateral mastectomy
○ signif greater complications in bilateral vs unilateral mastectomy ( ~20% vs 40%)
● Median progression-free survival time: longer in bilateral vs unilateral
○ bilateral mastectomy (542 days)
○ unilateral mastectomy (289 days)
● Significant risk factors for disease progression:
○ unilateral mastectomy
○ tumor ulceration
○ lymph node metastasis
○ tumors arising in the 4th mammary gland.
● Significant risk factors for disease-specific death:
○ lymph node metastasis
○ development of regional or distant metastasis.
○ unilateral mastectomy
● Treatment with chemotherapy was associated with a significantly decreased risk of disease-specific death
● Conclusion: results support bilateral mastectomy to improve progression free and disease specific survival time. Staged helps to decrease complication rate.

66
Q

Litterine-Kaufman JAVMA 19
prevalence of mammary mass in dogs

A

● 85% classified as benign, 15% classified as malignant
● Age, repro status, and quantity of masses (single v multiple) were not associated with malignancy
● Prevalence of malignancy in masses from the 4th mammary gland was significantly lower than that of the other 4 mammary glands combined