Chapter 8 Flashcards

(38 cards)

1
Q

Why do cells need to divide?

A

Reproduction
Growth
Repair
*Cell Theory= all cells come from cells**

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2
Q

How do bacteria divide?

A

1) The DNA replicates, then separates
2) Cell division begins as the plasma membrane grows inward, and a new cell wall is synthesized
3) Binary fission produces two identical daughter cells

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3
Q

Prokaryote cell division (Baccteria):

As the bacteria cell prepares to divide what happens?

A

As the bacteria cell prepares to divide a ring of protein forms at the centre of the cell
- This ring then constricts, pinching off the cell to form the two new cells

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4
Q

What makes Eukaryotic cell division more complex?

A

They have more things to separate such as multiple chromosome, nuclear envelope, and organelles

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5
Q

What part of cell division represents most of the cells life?

A

The Interphase (90% of the cells life)

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6
Q

What happens during the S Phase?

A
  • At the beginning of the S phase, the cell contains one copy of each chromosome
  • After being copied, the two copies stay together and are called chromatids
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7
Q

What happens at the end of the S phase?

A
  • All of the DNA has been copied
  • A second centrosome is made
  • The cell enters the G2 phase
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8
Q

What is the Mitotic Phase?

A

It is a highly orchestrated process of cell division

  • Sister chromatids are pulled apart
  • Cell contents are divided up
  • Cell splits in two (cytokinesis)
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9
Q

What happens during Interphase? PMAT?

A
Interphase = cell growth & Component duplication
PMAT = Component separation & division
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10
Q

Centromere

A

A region of DNA beneath kinetochore proteins

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11
Q

What happens during the Prophase stage?

A

It marks the entry of the cell into mitosis

  • Condensation of chromosomes
  • Breakdown of nuclear envelope
  • Nucleoli disappears
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12
Q

What are the duplicated chromosome composed of?

A

2 sister chromatids

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13
Q

What happens during the Prometaphase?

A
  • Nuclear envelope is completely dissociated

- Sister chromatids attach to mitotic spindle

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14
Q

What binds to the kinetochore structure? then what happens?

A

Spindle microtubules

Then the chromosome are attached to each spindle pole through microtubules

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15
Q

What happens during the Metaphase stage?

A
  • The mitotic spindle is fully formed
  • Centrioles are polarly localized
  • Centromeres of the chromosomes line up at the equator of the cell
  • The mitotic spindle anchors a kinetochore(protein) to each pole
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16
Q

What happens during the Anaphase stage?

A

Chromosome are split apart and moved to the poles of the cell by the kinetochore motor proteins

17
Q

T or F:

The tighter the microtubules pull, the tighter the kinetochore holds on (chinese finger trap)

18
Q

What happens during the Telophase stage?

A
  • Nuclei begins to reform
  • Chromatin unfolds
  • Nucleoli reappear
  • Mitotic fibres disappear
  • Cleavage furrow/ cell plate start to form
19
Q

Kinetochore

A

A set of proteins that pull the chromosomes apart

20
Q

What is the result of cell division?

A

Results in the sister chromatids being separated, and two genetically identical cells being produced

21
Q

What happens during the Cytokinesis?

A

The division of the duplicated cell into two daughter cells

22
Q

In animal cells, how is the cleavage furrow formed?

A

The cleavage furrow is formed by a contractile ring

- As the ring shrinks, it pinches off the connection between the two cells until they separate completely

23
Q

How do plant cells separate?

A

In plants cells, a new portion of the cell wall must be made to separate the two new cells.
- The cell plate forms from the centre blocking the connection between the two cells

24
Q

How does a cell know when to divide?

A

Cellular signals tell the cell when, and when not to divide, regulation is partly due to hormone activity
- The internal systems of the cell will check to make sure the cell is healthy and ready to divide

25
G1 Checkpoint
- Determines if conditions are good for cell division | - Checks for DNA damage
26
G2 Checkpoint
- Makes sure all DNA has been copied - Also checks for DNA damage - Ensures presence of proteins needed for M-phase
27
M Checkpoint
- Senses the intactness of the spindle
28
What do the checkpoints work through?
The checkpoints work through a set of proteins called Cyclins and CDKs (tell the cell to pass the checkpoint)
29
Cyclins
Binds to CDKs to turn them on
30
How much cyclins are needed?
The amount of specific cyclins varies during the cell cycle depending on other cellular cues
31
Can signals that regulate the rate of cell division come from outside the cell?
Yes some do
32
Which is more important? Stopping cell division? OR Activating it?
Stopping cell division is more important than activating it
33
What ability to cells have? | * Placed in glass box*
Cells have the ability to detect neighbours and only grow to fill the available space - Cells that are removed will be replaced and then the division will again stop
34
How can we get extra cell growth?
Extra growth can be stimulated by the addition of growth factors, or by damage to regulatory genes
35
In animals, what can uncontrolled cell division lead to?
Cancerous growths, colon cancer development | * Cells start to grow where they arent suppose to
36
How could we stop a cell from dividing?
Kill the cell that is growing too fast or stop the checkpoint
37
What regulatory mechanisms do cells use to determine when to undergo mitosis?
Cells signals, checkpoints
38
How does the loss of control of cell division lead to cancerous growth?
Not controlling, happens too fast