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Flashcards in chapter3 tissue renewal and regeneration Deck (146)
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1

Results in the complete restitution of the lost damage or tissue.

Regeneration

2

The process by which there is extensive deposition of collagen.

Fibrosis

3

The following are examples of labile tissues EXCEPT:A. Skin epitheliaB. Oral cavityC. Parenchymal cells of the liverD. Lining mucosa of all the excretory ducts

C. Parenchymal cells of the liver

4

Mechanism of stem cells in which with each stem cell division, one of the daughter cells retains its self-renewing capacity while the other enters differentiation.

Obligatory asymmetric replication

5

Stem cell mechanism in which there is a balance between self-renewing and differentiated cells.

Stochastic differentiation

6

A change in differentiation of a cell from one type to another is known as ________________.

Transdifferentiation

7

The capacity of a cell to transdifferentiate into diverse lineages is referred to as ___________.

Developmental plasticity

8

Somatic stem cells generate rapidly dividing cells called __________.

Transit amplifying cells

9

The liver contains stem cells/progenitor cells in the _____________.

Canals of Hering

10

Neural precursor cells are found in which two areas of the adult brain.

Subventricular zone and dentate gyrus of the hippocampus

11

This is the rate limiting step for replication in the cell cycle.

Restriction point between G1 and S.

12

This step in cell cycle monitors the integrity of DNA BEFORE replication.

G1/S checkpoint

13

Aids in cell scattering and proliferation.

HGF/Scatter factor

14

Most potent growth factor for vasculogenesis and angiogenesis.

VEGF

15

Growth factor responsible for migration and proliferation of fibroblasts, smooth muscles

PDGF

16

Growth factor that acts as a growth inhibitor and a potent fibrinogenic agent.

TGF-B

17

The following are biochemical pathways that utilize intrinsic tyrosine kinase activity EXCEPT:A. PI3 Kinase PathwayB. MAP-kinase PathwayC. IP3 PathwayD. cAMP Pathway

D. cAMP Pathway

18

Mobilization of endothelial stem cells and has a role in inflammation.A. VEFGR-1B. VEFGR-2C. VEFGR-3D. None of the above

A. VEFGR-1

19

Acts on lymphatic endothelial cells to induce lymphangiogenesis.A. VEFGR-1B. VEFGR-2C. VEFGR-3D. None of the above

C. VEFGR-3

20

Located in endothelial cells and many other cells types and considered to be the main receptors for vasculogenic and angiogenic effect on VEGF.A. VEFGR-1B. VEFGR-2C. VEFGR-3D. None of the above

B. VEFGR-2

21

Also known as the wear and tear pigment.

Lipofuschin

22

Provide resilience and lubrication to many types of CT (cartilage in joints).

Hyaluronan

23

This is the most abundant glycoprotein in BM.

Laminin

24

Mobilization of endothelial stem cells and has a role in inflammation.A. VEFGR-1B. VEFGR-2C. VEFGR-3D. None of the above

A. VEFGR-1

25

Acts on lymphatic endothelial cells to induce lymphangiogenesis.A. VEFGR-1B. VEFGR-2C. VEFGR-3D. None of the above

C. VEFGR-3

26

Located in endothelial cells and many other cells types and considered to be the main receptors for vasculogenic and angiogenic effect on VEGF.A. VEFGR-1B. VEFGR-2C. VEFGR-3D. None of the above

B. VEFGR-2

27

Also known as the wear and tear pigment.

Lipofuschin

28

Provide resilience and lubrication to many types of CT (cartilage in joints).

Hyaluronan

29

This is the most abundant glycoprotein in BM.

Laminin

30

What is REPAIR?

Repair, sometimes called healing, refers to the restoration
of tissue architecture and function after an injury.

 


(By convention, the term repair is often used for parenchymal
and connective tissues and healing for surface epithelia,
but these distinctions are not based on biology and we
use the terms interchangeably.)

Critical to the survival of
an organism is the ability to repair the damage caused by
toxic insults and inflammation. Hence, the inflammatory
response to microbes and injured tissues not only serves to
eliminate these dangers but also sets into motion the
process of repair.

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