CHEMBANK Flashcards
(1 cards)
1
Q
What is ChemBank and what are its key features and applications?
A
ChemBank: A public repository for small molecule chemical compounds focused on drug discovery and biological activity studies.
Website: http://chembank.broadinstitute.org
Key Features:
- Chemical Library: Collection of small molecules with structures and biological activities.
- Biological Assays: Data from high-throughput screenings (HTS) of chemical compounds.
- Target Information: Details on biological targets interacting with compounds.
- Data Mining & Analysis: Tools for predicting drug-likeness and patterns between structure and activity.
- Structure-Activity Relationships (SAR): Links chemical structure to biological effects.
- Public Access: Free for global research, allowing data download.
Applications:
Drug Discovery: Identify potential drug candidates and leads.
Chemical Genomics: Study small molecule effects on genes/cellular pathways.
Toxicology Studies: Investigate compound toxicity.
Disease Research: Explore links between small molecules and disease mechanisms.
