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Chemo drugs > Chemo drugs > Flashcards

Chemo drugs Flashcards

(24 cards)

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1
Q

Most cytotoxic

A

Alkylating agents

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2
Q

Nonphase specific

A

Alkylating agents

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3
Q

Abnormal base pairing

A

Alkylating agents

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4
Q

Intercalation/sliding between base pairs

A

Antitumor agents

Bleomycin, Dactinomycin

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5
Q

Derived from Actinomyces

A

Bleomycin, Dactinomycin

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6
Q

Structural analogs of DNA bases

A

Antimetabolites

5FU,MTX, Hydroxyurea

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7
Q

False substitution in DNA synthesis

A

Antimetabolites

5FU, MTX, Hydroxyurea

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8
Q

cleaves asparagine=protein synthesis inhibition

A

Enzyme

Asparaginase

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9
Q

Affect cell growth

A

Cytokines

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10
Q

BCR-ABL Inhibitor

A

BRCLAW
KAMAY=Ima
Imatinib

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11
Q

Tyrosine Kinase inhibitor

A

(Dasa Nilo Bosu Pona)Puna dasa nahilo busog
Dasatinib Nilotinib Bosutinib Ponatinib

axitinib (Inlyta)
dasatinib (Sprycel)
erlotinib (Tarceva)
imatinib (Glivec)
nilotinib (Tasigna)
pazopanib (Votrient)
sunitinib (Sutent)
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12
Q

Histone Deacetylase Inhibitor

A

Voring no History/stat. History of Romy=deep sin

Vorinostat, Romidepsin

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13
Q

DNA Methyltransferase Inhibitors

A

AZA makatransfer sa SITE-DES ITA BIN

Azacytidine, Decitabine

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14
Q

MTOR Pathway inhibitors

A

TEMSIROL-EVER limos

Temsirolimus-Everolimus

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15
Q

EGFR Pathway inhibitors

A

Errrrrr Loti nib-LAPA tinib

Erlotinib, Lapatinib

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16
Q

Multikinase inhibitors

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A

in reGORA-SORA-AXIT-VANDETA-CABOZAT-SUN-PANZO-

Regorafenib-sorafenib-Axitinib-Vandetanib-Cabozatinib-Sunitinib-Panzopanib

17
Q

Proteasome inhibitors

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A

Borteeozome, Car Fill Some IB

Bortezomib, Carfilzomib

18
Q

CD20

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A 
TOASTED IBRIT OPATO RITU 
rituximab
ofatumumab
ibritumomab
tositumomab
19
Q

CD52

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A

52 Lemtuso-maboy

Alemtuzumab

20
Q

CD30

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A

Brent-trenta

Brentuximab

21
Q

Growth Factor EGFR

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A

C2ximab-Pan itu mumab

cetuximab, Panitumumab

22
Q

Growth Factor HER2

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A

trast-pertuzu

Trastuzumab, Pertuzumab

23
Q

Growth Factor VEGF

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A

BABE A SEESAW MAB

Bevacizumab

24
Q

Others

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A

IPILIT MO MAB

Ipilimumab

Chemo drugs (6 decks)

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