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Flashcards in Chemotherapy Deck (11):
1

Fosfomycin

Inhibits pyruvyl transferase

2

How does bacitracin work?

Binds Mg++ and bactoprenol pyrophosphate, preventing cycling

3

B lactam antibiotics include

Penicillins, cephalosporins, monobactams and carbapenems.

4

What targets elongation factor G?

spectinomycin and fusidic acid

5

What targets aminoacyl tRNA binding?

Paramomycin, streptomycin

6

What targets 50S subunit?

Chloramphenicol, clindamycin, linezolid. Also 14-membered macrolides like erythromycin

7

fluconazole

targets enzymes in ergosterol biosynthesis

8

amantidine

blocks M2 channel

9

oseltamivir, zanamivir

blocks neuraminidase

10

cidofovir

phosphonate analogue of cytosine, inhibits the DNA pol of HCMV

11

foscarnet

pyrophosphate analogue, inhibits DNA pol of HCMV