Chemotherapy Flashcards
(11 cards)
1
Q
Fosfomycin
A
Inhibits pyruvyl transferase
2
Q
How does bacitracin work?
A
Binds Mg++ and bactoprenol pyrophosphate, preventing cycling
3
Q
B lactam antibiotics include
A
Penicillins, cephalosporins, monobactams and carbapenems.
4
Q
What targets elongation factor G?
A
spectinomycin and fusidic acid
5
Q
What targets aminoacyl tRNA binding?
A
Paramomycin, streptomycin
6
Q
What targets 50S subunit?
A
Chloramphenicol, clindamycin, linezolid. Also 14-membered macrolides like erythromycin
7
Q
fluconazole
A
targets enzymes in ergosterol biosynthesis
8
Q
amantidine
A
blocks M2 channel
9
Q
oseltamivir, zanamivir
A
blocks neuraminidase
10
Q
cidofovir
A
phosphonate analogue of cytosine, inhibits the DNA pol of HCMV
11
Q
foscarnet
A
pyrophosphate analogue, inhibits DNA pol of HCMV
