Cholesterole-Lowering Meds

Question 1

Why do we need cholesterol?

Answer 1

• It makes hormones

Question 2

High Cholesterol and high blood pressure can lead to?

Answer 2

• Atherosclerosis (build-up of fatty streaks in arteries)

Question 3

Types of Cholesterol?

Answer 3

• Very low-density Lipoprotein (VLDL)
• Low-density protein (LDL) - Bad Cholesterol
• High-density protein (HDL) - Good Cholesterol

Question 4

Dyslipidemia (unhealthy cholesterol) is diagnosed via?

Answer 4

Blood tests.

Question 5

Medication options of Cholesterol?

Answer 5

• HMG-CoA reductase inhibitors (statins)
• Cholesterol absorption inhibitors
• Fibrates
• Bile-acid sequestrants
• Monoclonal antibodies
• Vitamin B3 (niacin)

Question 6

Facts about Statins?

Answer 6

• They help prevent heart attacks and strokes.
• They cause a decrease in LDL and VLDL cholesterol.

Question 7

Examples of Statins Medication?

Answer 7

(They end with “Vastatin”)

• Atorvastatin
• Lovastatin
• Pravastatin
• Rosuvastatin
• Simvastatin

Question 8

High yield concepts of Statins?

Answer 8

• Hepatotoxicity
• Myopathy & Rhabdomyolysis
• Time of Dose
• Food Interactions
• Contraindications

Question 9

Facts about Ezetimibe?

Answer 9

• Prescribed to lower cholesterol, Especially LDL.
• Its combined with other Statins.

Question 10

High yield concepts of Ezetimide?

Answer 10

• It well tolerated, when combined with a statin.
• Myopathy.
• Hepatotoxicity.

Question 11

Facts about Fibrates?

Answer 11

• Prescribed for patients with high triglyceride (VLDL) and LDL levels.

Question 12

Examples of Fibrates Medication?

Answer 12

• Fenofibrate
• Gemfibrozil

Question 13

High yield concepts of Fibrates?

Answer 13

• Myopathy
• Hepatotoxicity
• Diarrhea (Fibrates)
• Risk for Gallstones (Cholelithiasis)