Christie

Question 1

Triiodothyronine (T₃)

Answer 1

• 10% of Thyroid Hormone secretion
• Active Form

Question 2

What is the active form of Thyroid Hormone

Answer 2

T₃

Question 3

The parafollicular or C cells of the thyroid secrete

Answer 3

Calcitonin

Question 4

Which of the following statements about T₃ and T₄ is true

Answer 4

Use transport sytems to cross cell membranes

Question 5

What reaction does thyroid peroxides catalyze

Answer 5

• oxidation of iodide ion to I₂
• organification of I₂ into thyroglobulin
• coupling reactions

Question 6

What inhibits thyroid peroxidase

Answer 6

propylthiouracil

Question 7

What molecule transports the majority of thyroid hormones in the blood

Answer 7

Thyroid binding globulin

Question 8

When you suspect hyperthyroidism in a patient, what is the first test you should order.

Answer 8

TSH

Question 9

What is a effect of thyroid hormone

Answer 9

Increases the basal metabolic rate

Question 10

Iodide balance in the body

Answer 10

Most of the iodide in the thyroid is stored as thyroglobulin

Question 11

Thyroid function tests are used for:

Answer 11

• assess overall thyroid status
• evaluate the adequacy of levothyroxine therapy
• monitor the treatment of:
  
  • hyperthyroidism
  • hypothyroidism

Question 12

Not an indication for performing thyroid function testing?

Answer 12

Monitor the treatment of hypothyroidism

Question 13

What does not inhibit thyroid hormone function?

Answer 13

Increased TBG levels

Question 14

T or F: “Cold” thyroid nodules are most likely to be neoplastic than are “hot” nodules.

Answer 14

true

Question 15

Based on your present knowledge, what causes the abnormality shown here

Answer 15

Thyroglossal duct cyst

Question 16

2 year old child

Answer 16

Thyroxine

Question 17

What causes the condition seen in this infant?

Answer 17

Hypothyroidism

Question 18

Goiter

Answer 18

• Plummers syndrome is due to autonomous nodule in a multinodular goiter

Question 19

In this euthyroid individiual who is otherwise asymptomatic, which of the following is the most likely diagnosis for this lesion?

Answer 19

simple (diffuse) goiter

Question 20

What are autoimmune diseases?

Answer 20

Graves disease

Hashimoto’s thyroiditis

Question 21

35 year old lady

Answer 21

Graves Disease

Question 22

50 year old lady

Answer 22

Hasimotos disease

Question 23

Thyroid cancer

Answer 23

Cancers metastatic to the thyroid are common

Question 24

Which of the following neoplasms is most likely to metastasize to the thyroid gland?

Answer 24

renal cell carcinoma

Question 25

Which of the following thyroid neoplasms has the worst prognosis?

Answer 25

anaplastic carcinoma

Question 26

Which of the following thyroid carcinomas is most likely to stain for amyloid?

Answer 26

Medullary Carcinoma

Question 27

Not a feature of multiple endocrine neoplasia?

Answer 27

Same age at diagnosis as sporadic cancers

Question 28

Which cells secrete PTH.

Answer 28

Chief Cells

Question 29

What cells form bone

Answer 29

osteoblasts

Question 30

What is the abnormality shown here

Answer 30

Parathyroid adenoma

Question 31

40 year old man

Answer 31

Parathyroid adenoma

Question 32

A lady with lung cancer exhibits the signs and symptoms of hypercalcemia yet here PTH is decreased. What is the cause of her hypercalcemia

Answer 32

Hypercalcemia of malignancy due to PTHrP secretion

Question 33

What is the most common cause of hypocalcemia in a hospitlized patient?

Answer 33

Decreased serum albumin

Question 34

Net effect of Vitamin D:

Answer 34

* Increase blood calcium and phosphorus levels

Question 35

Effect of calcitriol

Answer 35

* Increases calcium and phosphate

Question 36

T or F: In tertiary hyperparathyroidism, a patient with secondary hyperparathyroidism develops autonomous and excessive parathyroid activity often due to development of an adenoma

Answer 36

True

Question 37

Which type of MEN would be most likely in an individual with the lesions o fthe tongue shown in this illustration?

Answer 37

MEN 2b

Question 38

What is secreted by the adrenal gland?

Answer 38

* Cortisol * Aldosterone * Catecholamines * DHEA

Question 39

What is primarily responsible for production of DHEA

Answer 39

Zona reticularis

Question 40

45 year old man

Answer 40

Exogenous corticosteroids

Question 41

19 year old

Answer 41

Neisseria meningitidis

Question 42

52 year old woman

Answer 42

Autoimmune destruction of the adrenals

Question 43

45 year old man

Answer 43

increased urinary free catecholamines

Question 44

Not effect of cortisol?

Answer 44

Decreased breakdown of proteins

Question 45

Most common cause of Cushing Syndrome?

Answer 45

exogenous/latrogenic corticosteroid administration

Question 46

Responsible for most symptoms of hyperaldosteronism?

Answer 46

Hypokalemia

Question 47

T or F: The distinction between metabolic syndrome and cushing syndrome is made on the basis of the anabolic changes produced by Cushing syndrome.

Answer 47

False