Circulatory system Flashcards

(57 cards)

1
Q

What are the functions of the circulatory system?

A

Transport oxygen/nutrients, remove CO₂ and waste, carry hormones, maintain pH and water/ion balance, regulate body temperature, protect against disease, and clot to prevent blood loss.

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2
Q

What is the normal body temperature regulated by the circulatory system?

A

37°C.

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3
Q

How much blood does a woman typically have?

A

4-5 litres.

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4
Q

How much blood does a man typically have?

A

5-6 litres.

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5
Q

What percentage of blood is plasma?

A

55%

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6
Q

What is plasma mostly made of?

A

91% water and 9% dissolved substances (like O₂, CO₂, nutrients, waste).

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7
Q

What are the formed elements in blood?

A

Red blood cells(erythrocytes), white blood cells(leukocytes), and platelets(thrombocytes) 45% of blood volume.

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8
Q

What shape are red blood cells?

A

Biconcave.

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9
Q

What percentage of blood volume do RBCs make up?

A

40–45% (hematocrit).

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10
Q

Why don’t RBCs have nuclei?

A

More room for haemoglobin and increased flexibility.

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11
Q

How long do RBCs live?

A

About 120 days.

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12
Q

What is the main function of WBCs?

A

Remove dead/injured cells and protect against infection.

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13
Q

Where are WBCs made?

A

Bone marrow, spleen, lymph nodes, and thymus.

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14
Q

What are lymphocytes?

A

WBCs involved in immune response.

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15
Q

What are platelets?

A

Small cell fragments with no nucleus, involved in clotting.

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16
Q

How long do platelets live?

A

About 7 days.

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17
Q

What happens during vasoconstriction?

A

Arterioles constrict to reduce blood flow after injury.

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18
Q

What is a platelet plug?

A

Platelets stick to the vessel wall and each other to block a hole.

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19
Q

What is coagulation?

A

Blood clotting with RBCs, platelets, and fibrin to form a thrombus.

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20
Q

What is clot retraction?

A

Fibrin contracts, drying to form a scab.

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21
Q

How is oxygen transported in the blood?

A

3% dissolved in plasma, 97% bound to haemoglobin (oxyhaemoglobin).

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22
Q

What makes RBCs ideal for transporting oxygen?

A

No nucleus and biconcave shape.

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23
Q

What color is oxygenated blood?

A

Bright red (in arteries, except pulmonary artery).

24
Q

What color is deoxygenated blood?

A

Dark red or purple (in veins, except pulmonary vein).

25
How is CO₂ transported in blood?
7-8% dissolved in plasma, 22% on haemoglobin (carbaminohaemoglobin), 70% as bicarbonate ions.
26
What is the chemical formula for CO₂ transport as bicarbonate?
CO₂ + H₂O ⇌ H₂CO₃ ⇌ H⁺ + HCO₃⁻.
27
What nutrients are transported in plasma?
Glucose, amino acids, vitamins.
28
What inorganic substances are transported?
Na⁺, K⁺, Ca²⁺ ions.
29
What are some metabolic wastes?
Urea, creatinine, uric acid.
30
What muscle type is the heart made of?
Cardiac muscle.
31
Where is the heart located?
In the mediastinum, behind and slightly left of the sternum.
32
What surrounds the heart and why?
The pericardium; it anchors, protects, and allows movement.
33
What are the heart’s upper chambers?
Atria (right and left).
34
What are the heart’s lower chambers?
Ventricles (right and left).
35
Trace the flow of blood through the heart.
Body → Right atrium → Right ventricle → Lungs → Left atrium → Left ventricle → Body.
36
Why is the left ventricle wall thicker?
It pumps blood to the entire body.
37
What do heart valves do?
Ensure one-way blood flow.
38
What are atrioventricular valves supported by?
Chordae tendineae attached to papillary muscles.
39
What do semi-lunar valves do?
Control flow into the aorta and pulmonary artery.
40
What causes the 'lub-dub' sound?
Valve closure.
41
What are the 3 types of blood vessels?
Arteries, veins, and capillaries.
42
What do arteries do?
Carry blood away from the heart. (high pressure)
43
What's the largest artery in the body?
Aorta
44
What is vasoconstriction?
The vessel walls contract reducing blood flow.
45
What is vasodilation?
Vessel walls widen to increase blood flow.
46
What do capillaries do?
Connect arteries and veins; allow exchange of substances from capillary to cell and vice versa.
47
Why do veins have valves?
to prevent backflow due to the absence of pressure.
48
Major veins linking to the right atrium?
inferior vena cava (ascending from below heart) and superior vena cava (descending from above heart)
49
What happens during exercise?
cells produce more C02/lactic acid -> vasodilation to remove waste -> increase heart rate to increase cardiac output
50
What are the two phases of the cardiac cycle?
systole (contraction) and diastole (relaxation)
51
What happens during one heartbeat?
Diastole → Atrial systole → Ventricular systole.
52
What is cardiac output?
The volume of blood the heart pumps in a given time?
53
Blood group compatibility?
o- -> all o+ -> all + a- -> a-+, ab-+ a+ -> a+, ab+ b- -> b-+, ab-+ b+ -> b+, ab+ ab- -> ab-+ ab+ -> ab+
54
Steps of clotting?
1. vasoconstriction to reduce blood flow to the area 2. Thrombocytes adhere to the exposed collagen in the vessel wall to form a platelet plug 3. coagulation occurs RBCs and platelets against the wall have a protein fibrin mesh that incases them against the wall form a thrombus 4. Clot retraction; fibrin retracts and the clot dries to form a scab
55
Cardiac cycle?
1. both atria and ventricles in diastole (ventricle filling SL close AV open) 2. Atrial systole (and ventricular diastole) SL close remainng blood to RLV 3. Ventricular systole (and atrial diastole) AV close SL open pump out LA blood go in at RA
56
Blood transfusions:?
Whole blood, RBC concentrate, Plasma, Platelet, cryoprecipitate (Frozen plasma), immunoglobulins, autologous (blud to yourself)
57
agglutination?
erythrocytes clumping together example is a haemolytic disease at birth mother rh- baby is rh+ first go good anymore children die die