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Flashcards in CKD Deck (17)
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1

How is CKD defined?

damage to kidneys for decrease in function x3 mo

2

top 3 causes of CKD

DM
HTN
NSAIDs

3

S/S of CKD

Fatigue
HTN
+/- Urination
Edema
H2O/Electrolyte imbalances
Hematuria/Proteinuria
SCr/BUN
Decrease GFR

4

GFR for...
Stage 1
Stage 2
Stage 3a
Stage 3b
Stage 4
Stage 5

Stage 1: >90
Stage 2: 90-60
Stage 3a: 59-45
Stage 3b: 44-30
Stage 4: 29-15
Stage 5: <15

5

Describe...
Stage 1/2 CKD
Stage 3/4 CKD
Stage 5 CKD

Stage 1/2 CKD: structural abnormalities with preserved renal fxn
Stage 3/4 CKD: reduced function, symptomatic
Stage 5 CKD: ESRD

6

What is included in the W/U for CKD?

GFR: <60
Microalbuminuria (proteinuria)
UA (broad waxy casts)
Serum Electrolytes
High BUN/SCr
Abnormal: Hgb, Hct, low EPO, dysmorphic RBC

7

How do you Tx CKD?

ACEI/ARB/DI
Managecomorbidities (DM, HTN, Smoking)
Maintain Hgb
Dietary management
- restrict protein
- Ca/Vit D supplement
- limit: H2O, Na, K, Ph
- No NSAIDs
Hemodialysis (peritoneal)
Kidney Transplant

8

What are some systemic effects of CKD

Anemia
HTN
Prolonged bleeding
Dermatologic manifestations
Electrolyte manifestations
Bone manifestations

9

How do you dx glomerulonephirtis

Renal bx
UA (dysmorphic RBC, RBC casts)
Proteinuria
high BUN/SCr

10

what are examples of Nephrotic dzs

Minimal Change dz
Focal segmental GS
Membranous GN

11

What are examples of Nephritic

Post infectious GN
Crescentic GN
IgA

12

Nephrotic syndrome
Urine casts: _____
Proteinuria: _____
Hematuria: ______
Clinical features: ____

Urine casts: fatty casts
Proteinuria: >3.5 g/day
Hematuria: +/-
Clinical features: Generalized edema, periorbital edema, HTN

13

Nephritic syndrome
Urine casts: _____
Proteinuria: _____
Hematuria: ______
Clinical features: ____

Urine casts: RBC casts
Proteinuria: <3.5 g/day
Hematuria: ++ (coca-cola urine)
Clinical features: HTN, Edema

14

what can cause Acid/Base issues?

M: Methanol (Metformin)
U: Uremia
D: Diabetic Ketoacidosis
P: Paraldeyhde
I: Iron, Isoniazid (intoxication)
E: Ethylene glycol
S: Salicylates

15

what causes alcoholic ketoacidosis?
- Labs?
- Tx?

poor nutritional status w/ abrupt EtOH cessation or binge drinking
Labs: low K/Na+
Fomepizole

16

what is the result of Chronic ASA use?

Peptic ulcer, wheezing, tinnitus

17

what is the result of chronic Tylenol use?

Steatosis (non-alcoholic fatty liver dz)