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Buzz Words First Aid > Classic Lab Findings 2 > Flashcards

Classic Lab Findings 2 Flashcards

(70 cards)

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1
Q

Hypercoagulability (leading to DVTs and vasculitis)

A

Trousseau’s syndrome (adenocarcinoma of pancreas or lung)

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2
Q

hypersegmented neutrophils

A

megaloblastic anemia (B12 deficiency–neurologic symptoms vs folate deficiency–no neurologic symptoms)

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3
Q

hypertension, hypokalemia, metabolic alkalosis

A

Conn’s syndrome

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4
Q

hypochromic, microcytic anemia

A

iron deficiency anemia, lead poisoning, thalassemia

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5
Q

increased alpha-fetoprotein in amniotic fluid/maternal serum

A

Usually dating error, can also be anencephaly, spina bifida (neural tube defects)

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6
Q

increased uric acid levels

A

Gout, Lesch-Nyhan syndrome, tumor lysis syndrome, loop and thiazide diuretics

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7
Q

intranuclear eosinophilic droplet like bodies

A

Cowdry type A bodies (HSV or CMV)

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8
Q

iron containing nodules in alveolar septum

A

ferruginous bodies (asbestosis: increased risk of mesothelioma)

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9
Q

keratin pearls on skin biopsy

A

squamous cell carcinoma

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10
Q

large lysosomal vesicles in phagocytes, immunodeficiency

A

Chediak-Higashi disease (congenital failure of phagolysosome formation)

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11
Q

“lead pipe” appearance of color on barium enema xray

A

ulcerative colitis (loss of haustra)

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12
Q

linear appearance of IgG deposition on GMB

A

Goodpasture’s syndrome

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13
Q

low serum ceruloplasmin

A

Wilson’s disease (hepatolenticular degeneration)

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14
Q

“lumpy bumpy” appearance of glomeruli on immunofluorescence

A

Post-streptococcal glomerulonephritis (immune complex deposition of IgG and C3b)

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15
Q

lytic “hole punched” bone lesions on xray

A

Multiple Myeloma

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16
Q

mammary gland blue domed cyst

A

fibrocystic change of the breast

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17
Q

monoclonal antibody spike

A

multiple myeloma (IgG or IgA), MGUS, Waldenstroms macroglobulinemia (IgM), Primary amyloidosis

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18
Q

mucin filled cell with peripheral nucleus

A

signet ring cell (gastric carcinoma)

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19
Q

narrowing of bowel lumen on barium xray

A

string sign, Crohn’s disease

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20
Q

needle-shaped negatively birefringent crystals

A

Gout (monosodium urate crystals)

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21
Q

necrotizing vasculitis (lungs) necrotizing glomerulonephritis

A

granulomatosis with polyangitis (Wegner’s C-ANCA), and Goodpasture’s syndrome (Anti GBM)

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22
Q

nodular hyaline deposits in glomeruli

A

KW nodules (kimmelstiel-Wilson) seen in Diabetics

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23
Q

novobiocin response

A

sensitive: Staph epidermisis, resistant: Staph saprophyticus

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24
Q

nutmeg appearance of liver

A

chronic passive congestion of liver due to right heart failure

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25
"onion skin" periosteal reaction
Ewing's Sarcoma (malignant round cell tumor)
26
optochin response
sensitive: strep pneumo, resistant: strep viridans
27
periosteum raised fem bone, creating triangular area
codman's triangle on X-ray, (osteosarcome, ewing's sarcoma, pyogenic osteomyelitis)
28
podocyte effusion or "effacement" on EM
minimal change disease (child with nephrotic syndrome)
29
polished ivory like appearance of bone at cartilage erosion
eburnation (OA--resulting in bony sclerosis)
30
protein aggregates in neurons from hyperphosphorylation of protein tau
neurofibrillary tangles (alzheimer's disease), and Pick's bodies
31
psammoma bodies
meningioma, papillary thyroid carcinoma, mesothelioma, papillary serous carcinoma of the endometrium and ovary
32
psedopalisading tumor cells on brain biopsy
Glioblastoma multiforme
33
RBC casts in urine
acute glomerulonephritis
34
rectangular, crystal-like, cytoplasmic inclusions in leydig cells
reinke crystals (leydig cell tumor)
35
renal epithelial casts in urine
acute toxic/viral nephrosis
36
rhomboid crystals, positively birefringent
pseudogout (calcium pyrophosphate dihydrate crystals)
37
rib notching
coarctation of the AO
38
ring enhancing brain lesions in AIDs
toxoplasma gondii, CNS lymphoma
39
sheets of medium sized lymphoid cells with scattered pale tangible body-laden macrophages (starry sky histology)
Burkitt's lymphoma t(8,14) c-myc activation, associated with EBV, black sky=malignant cells
40
silver staining spherical aggregation of tau proteins in neurons
Pick Bodies (pick's disease= progressive dementia, changes in personality)
41
"soap bubble" in femur or tibia on xray
giant cell tumor of bone (usually benign)
42
"spikes" on basement membrane, "dome-like" sub epithelial deposits
Membranous glomerulonephritis (may progress to nephrotic syndrome)
43
stacks of RBCs
rouleux formation (high ESR, multiple myeloma)
44
stippled vaginal epithelial cells
clue cells (gardnerella vaginalis)
45
Tennis racket shaped cytoplasmic organelles in Langerhans cells
birbeck granules (langerhans cell histiocytosis or histiocytosis X: eosinophilic granuloma)
46
thrombi made of white/red layers
Lines of Zahn (arterial thrombus, layers of platelets and RBCs)
47
Thumb sign on lateral xray
Epiglottitis (Haemophilus influenzae)
48
Tram track appearance of capillary loops of glomerular basement membranes on LM
Membranoproliferative glomerulonephritis
49
triglyceride accumulation in liver cell vacuoles
fatty liver disease (alcoholic or metabolic syndrome)
50
Waxy casts wit very low urine flow
chronic ESRD
51
WBC casts in urine
acute pyelonephritis
52
WBCs that look smudged
CLL
53
wire loop glomerular capillary appearance on light microscopy
Lupus nephropathy
54
yellowish CSF
Xanthochromia (subarachnoid hemorrhage)
55
sheets of medium sized lymphoid cells with scattered pale tangible body-laden macrophages (starry sky histology)
Burkitt's lymphoma t(8,14) c-myc activation, associated with EBV, black sky=malignant cells
56
silver staining spherical aggregation of tau proteins in neurons
Pick Bodies (pick's disease= progressive dementia, changes in personality)
57
"soap bubble" in femur or tibia on xray
giant cell tumor of bone (usually benign)
58
"spikes" on basement membrane, "dome-like" sub epithelial deposits
Membranous glomerulonephritis (may progress to nephrotic syndrome)
59
stacks of RBCs
rouleux formation (high ESR, multiple myeloma)
60
stippled vaginal epithelial cells
clue cells (gardnerella vaginalis)
61
Tennis racket shaped cytoplasmic organelles in Langerhans cells
birbeck granules (langerhans cell histiocytosis or histiocytosis X: eosinophilic granuloma)
62
thrombi made of white/red layers
Lines of Zahn (arterial thrombus, layers of platelets and RBCs)
63
Thumb sign on lateral xray
Epiglottitis (Haemophilus influenzae)
64
Tram track appearance of capillary loops of glomerular basement membranes on LM
Membranoproliferative glomerulonephritis
65
triglyceride accumulation in liver cell vacuoles
fatty liver disease (alcoholic or metabolic syndrome)
66
Waxy casts wit very low urine flow
chronic ESRD
67
WBC casts in urine
acute pyelonephritis
68
WBCs that look smudged
CLL
69
wire loop glomerular capillary appearance on light microscopy
Lupus nephropathy
70
yellowish CSF
Xanthochromia (subarachnoid hemorrhage)

Buzz Words First Aid (6 decks)

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