Classic/Relevant Treatments Flashcards by Josh Wohlgemuth

Breast cancer in postmenopausal women

Aromatase inhibitor (anastrazole)

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Streptococcus pyogenes

Penicillin prophylaxis

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ADHD

Methylphenidate, amphetamines

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Acute promyelocytic leukemia (M3)

All-trans retinoic acid

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Bipolar disorder

Lithium, valproate, carbamazepine, lamotrigine (mood stabilizers)

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Ulcerative colitis

5-ASA, infliximab

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Pneumocystis jirovecii

Trimethoprim/sulfamethoxazole [TMP-SMX]; (prophylaxis in AIDS patients)

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Pheochromocytoma

alpha antagonists (e.g. phenoxybenzamine)

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Sporothrix schenkii

Oral potassium chloride

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Anticoagulation during pregnancy

Heparin

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SIADH

Demeclocycline, lithium, vasopressin receptor antagonist

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Ringworm infections

Terbinafine, griseofulvin, imidazole

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Infertility

Leuprolide, GnRH (pulsatile)

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Cystic fibrosis

N-acetylcysteine + antipseudomonal prophylaxis (tobramycin/azithromycin)

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Neural tube defect prevention

Prenatal folic acid

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Prostate carcinoma

Flutamide

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Pseudomonas aeruginosa

Antipseudomonal penicillin + aminoglycoside

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MRSA

Vancomycin

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Cytomegalovirus

Ganciclovir

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Chronic hepatitis

IFN-alpha

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Pulmonary arterial hypertension (idiopathic)

Sildenafil, bosentan, epoprostenol

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Hypercholesterolemia

Statin (first-line)

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Sickle cell anemia

Hydroxyurea (increases fetal hemoglobin)

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Neisseria meningitidis

Penicillin/ceftriaxone, rifampin (prophylaxis)

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*Chlamydia trachomatis*

Doxycycline (+ ceftriaxone for gonorrhea confection), erythomycin eye drops (prophylaxis in infants)

HER2/neu-positive breast cancer

Trastuzumab

Schizophrenia (negative symptoms)

5-HT2A antagonists (e.g. second generation antipsychotics)

Entercocci

Vancomycin/ampicillin + aminoglycoside

Osteomalacia/rickets

Vitamin D supplementation

Streptococcus bovis

Penicillin prophylaxis; evaluation for colon cancer if linked to endocarditis

Wegner's granulomatosis with polyangiitis

Cyclophosphamide, corticosteroids

Bulimia

SSRIs

*Mycobacterium tuberculosis*

RIPE (rifampin, isoniazid [INH], pyrazinamide, ethambutol)

Carcinoid syndrome

Octeotride

Influenza

Rimantadine, oseltamivir

Diabetes mellitus type 2

Dietary intervention, oral hypoglycemics, and insulin (possible)

Chronic gout

Probenecid (underexcretor), allopurinol (overproducer)

Erectile dysfunction

Sildenafil, vardenafil

Absence seizures

Ethosuximide

Heparin toxicity (acute)

Protamine sulfate

Diabetes mellitus type 1

Dietary intervention (low-sugar) + insulin replacement

Haemophilus influenzae (B)

Rifampin (prophylaxis)

Stable angina

Sublingual nitroglycerin

*Neisseria gonorrhoeae*

Ceftriaxone (add doxycycline to cover likely concurrent *Chlamydia*)

Alcohol withdrawal

Benzodiazepines

Diabetes insipidus

Desmopressin (central); hydrochlorothiazide, indomethacin, amiloride (nephrogenic)

Immediate anticoagulation

Heparin

*Clostridium botulinum*

Antitoxin

Warfarin toxicity

Fresh frozen plasm (acute), vitamin K (chronic)

Generalized anxiety disorder

Buspirone

Estrogen receptor (ER)-positive breast cancer

Tamoxifen

Patent ductus arteriosus

Indeomethacin

Prostate cancer/uterine fibroids

Leuprolide, GnRH (continuous)

*Candida albicans*

Amphotericin B (systemic), nystatin (oral thrush, esophagitis)

*Clostridium difficile*

Oral metronidazole; if refractory, oral vancomycin

Chronic myelogenous leukemia (CML)

Imatinib

Schizophrenia (positive symptoms)

D2 receptor antagonists (e.g. first and second generation antipsychotics)

Malaria

Choloroquine/mefloquine (for blood schiznot), primaquine (for liver hypnozoite)

UTI prophylaxis

Trimethoprim/sulfamethoxazole (TMP-SMX)

Arrhythmia in damaged cardiac tissue

Class IB antiarrhythmic (liocaine, mexiletine, tocainide)

Rickettsia rickettsii

Doxycycline, chloramphenicol (especially in context of aplastic anemia)

Toxoplasma gondii

Sulfadiazine + pyrimethamine

*Clostridium tetani*

Antitoxin + vaccine booster + diazepam

Depression

SSRIs (first-line)

Hyperaldosteronism

Spironolactone

Cyclophosphamide-induced hemorrhagic cystitis

Mesna

Ethylene glycol/methanol intoxication

Fomepizole (alcohol dehydrogenase inhibitor)

Leigonella pneumophila

Erythromycin

Prolactinoma

Bromocriptine/cabergoline (dopamine agonists)

*Cryptococcus neoformans*

Fluconazole (prophylaxis in AIDS patients)

B₁₂ deficiency

Vitamin B12 supplementation (work up cause with Schilling test)

Medical abortion

Mifepristone

Streptococcus pneumoniae

Penicillin/cephalosporin (systemic infection, pneumonia), vancomycin (meningitis)

Staphylococcus aureus

MSSA: nafcillin, oxacillin, dicloxacillin (antistaphylococcal penicllins); MRSA: vancomycin

Long-term anticoagulation

Warfarin

Tonic-clonic seizures

Phenytoin, valproate, carbamazepine

Diabetic ketoacidosis

Fluids, insulin, K+

Hypertriglyceridemia

Fibrate

Buerger's disease

Smoking cessation

*Trichomonas vaginalis*

Metronidazole (patient and partner)

Acute gout attack

NSAIDs, colchicine

Crohn's disease

Corticosteroids, infliximab

Treponema pallidum

Penicillin

Multiple sclerosis

Beta-interferon, immunosuppression, natalizumab

Malignant hyperthermia

Dantrolene

Alcohol abuse

AA and disulfiram for patients; AA for family

Benign prostatic hyperplasia

Tamsulosin, finasteride

Osteoporosis

Bisphosphonates; calcium and vitamin D supplementation

Migraine

Sumatriptan

Anorexia

SSRIs

Temporal arteritis

High-dose steroids

Classic/Relevant Treatments Flashcards

Provide the appropriate treatment for the given condition (91 cards)