Classification

Question 1

What are major type of epilepsy

Answer 1

2
* Generalized seizure
*Partial seizure

Generalized seizure
Generalized tonic-clonic seizure GTCS- (grand mal epilepsy)
Aura– loss of consciousness –fall on ground –tonic-clonic phase–period of relaxation –CNS depression

Absence seizure(petit mal epilepsy)
Sudden onset of staring –stoppage of activity –unresponsiveness c temporary loss of consciousness

Myoclonic seizure – single or multiple sudden,brief,shock like contraction

Partial seizure
Simple partial (SPS) - depend on cortex involve -
Convulsions (motor focal symptoms)
Paraesthesia(sensory symptoms)
- no loss of consciousness

Complex partial(CPS temporal lobe epilepsy, psychomotor epilepsy)
Aura– amnesia– abnormal behaviour and automation
Impaired consciousness

Question 2

Classification of antiepileptic drugs

Answer 2

Chemical classification
1. Hydantoin- phenytoin,fosphentoin
2.barbiturate- phenobarbitone
3. Carboxylic acid derivatives - sodium valporate
4. Succinimide- ethosuximide
5. BZDs- lorazepam, diazepam
6. Phenyltriazine- lamotrigine
7. Cyclic GABA analogue- Gabapentin,pregabalin
8.Im.inositol.benes - carbamazepine, oxcarbazepin
9. Newer - Topiramate,tiagabine