Clinical Applications

Question 1

Craniorachischisis Totalis

Answer 1

The ENTIRE neural tube fails to close properly

Results in a miscarriage

Question 2

Anencephaly

Answer 2

Incomplete development of the cranial Neural Tube

Results in a brain that is an undifferentiated and exposed mass

Question 3

Myeloschisis

Answer 3

Failure of a region of spinal cord to properly develop

Question 4

Inionschisis

Answer 4

Failure of the neural tube near the occipital region to fuse

Question 5

Spinal Dysraphism

Answer 5

Failure of Neural Tube to close, generally at the Cranial or Caudal Neuropore

Question 6

Spina Bifida

Answer 6

Failure of the vertebral arches to fuse due to spinal dysraphism

Question 7

Spinal Bifida Occulta

Answer 7

Single Vertebral Arch fails to fuse

Question 8

Spina Bifida vs Spinal Bifida Occulta

Answer 8

Spinal Bifida occulta: Failure of a single vertebral arch to fuse

Spina Bifida: Failure of the vertebral arches to fuse and neural tissues/meninges protruding