Clinical Pharmacy (Heart) Flashcards
(45 cards)
The spectrum of acute ischemia related syndromes ranging from UA to MI with or w/o ST elevation that are secondary to acute plaque rupture or plaque erosion
Acute Coronary Syndrome
Shortness of breath
Dyspnoea
Profuse perspiration
Diaphoresis
ECG
Electrocardiogram
A chest pain or
discomfort caused
when the heart muscle
doesn’t get enough
oxygen-rich blood.
Angina
most common form of angina, has a
more predictable pattern,
which is brought on by
exertion, emotional stress,
or a heavy meal , which is
usually relieved by rest ,
nitroglycerin.
Stable (Classic) Angina
Type of angina where rest angina, severe new-onset angina and increasing angina is experienced; Decreased response to rest or nitroglycerin
Unstable Angina
Unstable Angina
Usually is prolonged > 20
min occurring within a week of presentation
Rest Angina
Unstable Angina
angina with 2 months onset of initial
presentation
Severe New-Onset Angina
Unstable Angina
refers to previously
diagnosed angina that is distinctly more frequent, longer in duration, or lower in threshold
Increasing angina
Type of angina where there is coronary artery spasm, artery already has a fixed obstruction, usually occurs at rest, and CCBs are most effective rather than B-blockers.
Prinzmetal’s Angina
Other name for Prinzmetal’s Angina
Vasospastic/Variant
ALT
Alanine Amino Transferase
AST
Aspartate aminotransferase
Used in tx of angina
Nitrates
used in the immediate
treatment of unstable
angina and is used for longterm therapeutic relief .
Intravenous Nitroglycerine
This angina occurs in the
recumbent position and is not
specifically related to either rest
or exertion.
Angina decubitus
Other name of Angina decubitus
Nocturnal angina
reduce oxygen demand, both at rest and during exertion, by decreasing the heart rate and
myocardial contractility, which also decreases arterial
blood pressure
B-Blockers
Should be avoided in Prinzmetal angina and asmatha patients
B-Blockers
These agents prevent and reverse coronary spasm by inhibiting
calcium influx into vascular smooth muscle and myocardial muscle.
This results in increased blood flow, which enhances myocardial
oxygen supply
CCBs
used innstable (exertional) angina that is not controlled by nitrates and β-blockers and in patients
for whom β-blocker therapy is inadvisable
CCBs
death of myocardial cells from
inadequate oxygenation, often caused by a
sudden complete blockage of a coronary
artery; characterized by localized formation of
necrosis (tissue destruction) with subsequent
healing by scar formation and fibrosis
Myocardial Infarction
Drug used as pain relief for MI
Morphine