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Flashcards in Clinicians perspective Deck (27)
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1

How many deaths world wide did alcohol account for in 2012?

5.9%

2

In the UK what age range and gender is most affected by alcohol related deaths?

males between 55-64 years

3

How many deaths per 100,000 in the UK were related to alcohol?

14.2

4

How much does alcohol cost the NHS?

£3.5 bn

5

How much NHS spending is on alcohol related illness?

12%

6

How much does the drinks industry generate?

£11.5 bn

7

What are the medical consequences related to the ICD-10? (5)

1. withdrawal
2. Brain/NS effects
3. CVD
4. Liver
5. cancer

8

How many cancers does alcohol account for?

4%

9

How early can alcohol withdrawal start?

6-8 hours from last drink

10

How long does mild withdrawal last?

12- 36 hours

11

What symptoms occur in mild withdrawal? (5)

- fine tremor
- sweating
- anxiety
- raised heart rate and blood pressure
- anorexia and nausea

12

What symptoms occur in moderate withdrawal? (7)

- coarse tremor
- shaking
- agitation
- disorientation
- confusion
- seizures
- hallucinations

13

How long does moderate withdrawal last?

12 hrs - 5 days

14

How long does severe withdrawal last?

12 hrs - 7 days

15

What symptoms occur in severe withdrawal?

- severe agitation
- confusion
- delusions
- hallucinations
- circulatory collapse
- Delirium Tremens

16

Effects on the NS include (3)...

Peripheral neuropathy
Compression neuropathy
myopathy

17

Interactions of alcohol with cardio problems?

not a direct link for CVD but a J shaped graph
arrhythmias like holiday heart syndrome and long QT

18

What conditions in the liver are linked with alcohol? (3)

cirrhosis
alcohol related steatosis
alcohol related hepatitis

19

What are the key points about alcohol related steatosis? (3)

universal in alkies
weird LFTs
reverses with cessation

20

What kind of mortality is associated with alcohol related hepatitis?

high

21

what six treatments are used for the liver in alcohol related damage?

abstinence, vitamins, nutrition, drugs (beta blockers and rifaximin), TIPPS and transplant

22

What is the drink drive limit?

50-80mg per 100ml

23

What four drugs are used in withdrawal?

Acamprosate
Naltrexone
Disulphiram
Nalmefene

24

What does Acamprosate used for?

used for cravings

25

What is Naltrexone used for?

used for desire

26

What is Disulphiram used for?

used as aversion therapy

27

What is Nalmefene used for?

opioid antagonist