ClinPath 4 - csv

Question 1

1. Replicative form of chlamydia

Answer 1

Reticulate body

Question 2

2. Infectious stage of chlamydia

Answer 2

Elementary body

Question 3

3. The target cell of R. Rickettsii

Answer 3

Vascular endothelium

Question 4

4.Ornithosis

Answer 4

Chlamydophila psittaci

Question 5

5. Cell Lines used for diagnosis of Chlamydia infections

Answer 5

Mcoy and Buffalo Green Monkey Cells (both)

Question 6

6. B. Quintana

Answer 6

Trench Fever

Question 7

7. Fried egg colonies

Answer 7

Mycoplasma

Question 8

8. Chlamydia trachomatis can cause one of the following conditions

Answer 8

Both (ocular and genital disease)

Question 9

9. Antigen detected in chlamydial infection

Answer 9

LPS antigen

Question 10

10. Horder Spots

Answer 10

C. psittaci

Question 11

11. This organ was named TWAR?

Answer 11

C. pneumoniae

Question 12

12. AR39 is associated with?

Answer 12

From throat of a student with Pharyngitis

Question 13

13. TW-183

Answer 13

Isolated from eye of a control child in a trachoma vaccine

Question 14

14. IgM Antibody incubation period of C.pneumoniae

Answer 14

1-2 weeks (pero sa notes 2-3 weeks)

Question 15

15. Black ESCHAR suggests the presence of the ff infection?

Answer 15

C. Rickettsial Infection

Question 16

16. Rickettsial spp. Replication takes place in the?

Answer 16

Cytoplasm

Question 17

17. Rickettsial organism has

Answer 17

Gram negative cell wall

Question 18

18 Most severe form of rickettsial infection:

Answer 18

endemic murine epidemic rmsf

Question 19

21. Rickettsia Prowazeki

Answer 19

Epidemic Typhus

Question 20

22. Rickettsia rickettsii

Answer 20

RMSF (rocky mountain spotted fever)

Question 21

23. Rickettsia typhi

Answer 21

murine typhus

Question 22

24. Bartonella quintana

Answer 22

Trench fever

Question 23

25. Bartonella henselae

Answer 23

Cat scratch disease

Question 24

26. Which of the ff tumor markers is classified as a tumor suppressor gene?

Answer 24

BRCA1

Question 25

27. Which of the following is the most useful in using tumor analysis?

Answer 25

Monitoring recurrence

Question 26

28. Which is used for recurrence of ovarian cancer?

Answer 26

CA-125

Question 27

29. Which of the following tumor maker is used to monitor persons with breast cancer for recurrence of disease.

Answer 27

CA-15-3

Question 28

30. Tumor marker used to determine the usefulness of herceptin therapy in breast cancer

Answer 28

HER2

Question 29

31. A person is suspected of having testicular cancer. Which type of hCG test would be most useful?

Answer 29

Plasma immunoassay for intact hCG and b-hCG subunit

Question 30

19. Mild illness, wheezing, coryza and pneumonia is suggestive of?

Answer 30

Mycoplasma infection

Question 31

20. Considered as the smallest living organism.

Answer 31

Mycoplasma

Question 32

32. Increase Alpha Fetoprotein is usually associated with

Answer 32

Hepatocellular carcinoma

Question 33

33. Which of the following assays is recommended as a screening test for colorectal cancer in persons over 50 years old?

Answer 33

Occult blood

Question 34

34. Which of the following assay is used to determine the risk for development of cancer?

Answer 34

P53 gene mutation

Question 35

35. Which of the following is true about PSA?

Answer 35

Free PSA below 25% is nonmalignant

Question 36

36 Tumor marker as screening tool

Answer 36

PSA

Question 37

37. 65 yr old male with hemochromatosis, inadequately treated, status post left colon resection. On routine examination CEA level is elevated. CT scan shows no mass lesion. What is the likely reason for this?

Answer 37

Impaired liver function

Question 38

38. Tumor marker used for HEPATOCELLULAR CARCINOMA. in China:

Answer 38

AFP

Question 39

39. Tumor marker occurring in epithelial cells that become elevated during malignancies except

Answer 39

CEA

Question 40

40. Polypeptide hormone:

Answer 40

Alkaline phosphatase

Question 41

41. Mutation of p53 can be detected through:

Answer 41

PCR

Question 42

42. Tumor marker for the screening and identification of families or high-risk individuals

Answer 42

BRCA 1

Question 43

43. Recommendation for ordering tumor marker tests:

Answer 43

Order serial test in same laboratory using the same assay kit.

Question 44

44. Ectopic Tumor Marker EXCEPT:

Answer 44

CEA

Question 45

45. Female with sudden change on her bowel movement, no lesion on rectal area, positive on occult blood test, presence of 6cm mass. What tumor marker should be used?

Answer 45

CA 19-9

Question 46

46. Organ specific tumor marker.

Answer 46

PSA

Question 47

47. Which tumor marker is associated with Lewis Blood group?

Answer 47

CA 19-9

Question 48

48. A 79 yr old woman, previously healthy. Palpated a lump in her upper outer quadrant breast. Histologic test shows pleomorphic cells with increase N:C ratio and prominent nucleoli. Immunologic test shows negative HER2/neu, positive estrogen receptor, positive c. D marker. HER2/neu is indicative of?

Answer 48

Good Prognosis

Question 49

49. A 50 yr old man has had headaches and difficulty concentrating for the past 2 months. He then begins to exhibit odd behavior. He suffers a grand mass tissue and the sample is submitted to the hospital. MRI reveals a large mass with extensive necrosis in the left cerebral hemisphere. Which of the following tumor marker is most likely used?

Answer 49

Desmosterol

Question 50

50. A 50 yr old woman has headache. Has 5kg wt. Loss for the last few months, has decreased menstruation over the past 10 days, the physical examination, bilateral papiledema was noted. Ct scan revealed a marked decreased cerebral edema with effacement of lateral ventricles. Lab shows, Na 108, k 4.o cl 83 co2 14 glucose 82 creatinine 0.5 Which tumor markers is useful?

Answer 50

CgA