CNS Infection Flashcards
(48 cards)
Characteristic imaging triad of TB meningitis?
Hydrocephalus, Basal Enhancement and Infarcts
initial event in the neurosyphilitic infection which occurs in approx 25% of all cases of syphilis?
Meningitis
Most common form of neurosyphilis
Meningovascular syphilis
Tuberculomas may grow up to size of
range
2-12 mm
page 742
most frequent opportunistic fungal infection
Candidiasis
The following are true of Candidiasis, except:
a. antecedents include severe burns, use of TPN
b. with treatment of IV amphotericin B, the prognosis is good
c. Yeast can be seen on direct microscopy n half of the cases
d. no feature distinguishes candidiasis with other fungal infection
b. with treatment of IV amphotericin B, the prognosis is good
- even with treatment of IV amphotericin B, the prognosis is grave
page 753
Cerebral toxoplasmosis occurs in patients with HIV and CD4 counts below:
a. 400/ul
b. 200/ul
c. 100/ul
d. 50/ul
c. 100 /ul
page 755
Which of the following would be the first reaction to bacterial infection in the brain?
a. exudation of protein
b. migration of neutrophils into the pia and subarachnoid space
c. lymphocytes and histiocytes migrate into the area of infection
d. hyperemia of the meningeal venules and capillaries
d. hyperemia of the meningeal venules and capillaries
Signs and symptoms of headache, stiff neck, Kernig and Brudzinski signs would correlate with this pathological reaction:
a. pure pia-arachnoiditis
b. subpial encephalopathy
c. thrombosis of meningeal veins
d. inflammatory or vascular involvement of cranial nerves
a. pure pia-arachnoiditis
Table 31-1 page 721
Signs and symptoms of focal seizures, focal cerebral defects eg hemiparesis, aphasia would correlate with this pathological reaction:
a. pure pia-arachnoiditis
b. subpial encephalopathy
c. thrombosis of meningeal veins
d. inflammatory or vascular involvement of cranial nerves
c. thrombosis of meningeal veins
table 31-1
most sensitive and specific test for CSF rhinorrhea and otorrhea
B2 transferrin
household contacts of patients with meningococcal meningitis should be protected with antibiotic treatment. the following are recommended prophylactic treatment
,except:
a. rifampin 10 mg/kg q12 for 2 days in children
b. ciprofloxacin 500 mg once a day for 2 days
c. single dose of ciprofloxacin 500 mg
d. rifampin 600mg q12 hrs in adults for 2 days
except B
components of oslers triad
pneumococcal meningitis
pneumonia
endocarditis
which of the bacterial etiologies of encephalitis can cause GBS, cranial neuritis, acute myositis, aseptic meningitis, transverse myelitis, global encephalitis, seizures, cerebellitis? *
a. mycoplasma b, legionella c. bartonella d. anthrax e. listeria
a. mycoplasma
p 739
Which of the following bacterial etiologies of encephalitis can cause hemorrhagic and inflammatory CSF?
a. mycoplasma
b. legionella
c. bartonella
d. listeria
e. anthrax
e. anthrax
p 732
most common congenital heart defect associated with brain abscess
tetralogy of fallot
most frequent initial symptom of intracranial abscess?
a. seizure
b. focal neurologic deficit
c. headache
d. drowsiness
c. headache
p. 738
Most frequent initial symptom of intracranial abscess?
a. focal seizure
b. unilateral weakness
c. headache
d. drowsiness
e. confusion
c. headache
p. 738
which aspect of bacterial meningitis produces seizures
a. pia-arachnoiditis
b. subpial encephalopathy
c. hydrocephalus
d. inflammatory involvement of cranial nerve roots
b. subpial encephalopathy
table 31-1
Single most effective anti TB drug in treating tuberculous infections
a. Rifampin
b. Isoniazid
c. Pyrazinamide
d. Ethambutol
b. Isoniazid
Which anti TB medication is associated with optic neuropathy?
a. Rifampin
b. Isoniazid
c. Pyrazinamide
d. Ethambutol
d. Ethambutol
Which anti TB medication is associated with neuropathy and hepatitis?
a. Rifampin
b. Isoniazid
c. Pyrazinamide
d. Ethambutol
b. Isoniazid
Which is not a presentation of syphilis?*
a. tabes dorsalis
b. meningovascular meningitis
c. weils syndrome
d. dementia paralytica
e. spinal syphilis
c. Wiels syndrome
- extreme form of leptospirosis
inflammation and fibrosis of small arteries in meningovascular syphilis?
Heubner arteritis
