Cognition/intellect Flashcards

(49 cards)

1
Q

Visuospatial function

A

parietal lobe (R/L)
visuoconstruction
visuoperception
visuoorientation

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2
Q

Visuospatial function deficits

A

getting lost in familiar environments
visual distortions
agnosias
distortion: oscillopsia, macropsia

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3
Q

Executive function location

A

dorsolateral prefrontal cortex

posterior parietal lobe

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4
Q

Social cognition location

A

insular cortex
orbitofrontal cortex - response inhibition
anterior cingulate -drive, motivation

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5
Q

Dementia

A
impaired cognition
impaired function
not related to a medical condition/medication
decline from previous function
not related to learning disability
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6
Q

Examples of dementia

A
Alzheimer's 
vascular
Lewy Body
Frontotemporal
Parkinson's disease
Huntington's
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7
Q

Neuropathology of dementia

A

misfolded proteins
Alzheimer’s - beta amyloid
Parkinson’s/lewy body

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8
Q

Selective vulnerability to dementia

A

certain protein aggregates have affinity to certain anatomic regions
Cell death/dysfunction in those regions
does not work 100% of the time
DDx for corticobasilar syndrome

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9
Q

Recall neuroanatomy

A

dorsolateral prefrontal cortex

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10
Q

Attention/working memory neuroanatomy

A

dorsolateral prefrontal cortex

posterior parietal lobe

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11
Q

Language neuroanatomy

A

Primary auditory cortex
Wernicke’s
Broca’s

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12
Q

Pentagon test neuroanatomy

A

parietal
visual cortex
inferior temporal lobes

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13
Q

3 step command test neuroanatomy

A

dorsolateral prefrontal cortex

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14
Q

MOCA

A

screening
more difficult
better at picking up mild cognitive impairment - 80% sensitivity

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15
Q

Orientation to time/place brain area

A

temporal

frontal

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16
Q

Orientation to time/place in dementia

A

impaired relatively late in course of dementia

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17
Q

Orientation to person brain area

A

SELF: medial prefrontal and posterior cingulate cortex
OTHERS: fusiform gyrus (occipitltemporal gyrus) in temporal lobe

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18
Q

Orientation to person in dementia

A

impaired very late

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19
Q

Immediate recall impairment brain area

A

Wernicke, Broca, Arcuate fasciculus

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20
Q

Immediate recall impairment in dementia

21
Q

Delayed recall (2-3 min) impairment brain area

A

Hippocampus

medial temporal lobe (high density of NFT, NP)

22
Q

Delayed recall impairment in dementia

A

AD > FTD

AD –> rapid rate of forgetting for 10 minutes

23
Q

Spelling brain area

A
prefrontal
frontal dorsolateral
inferior dorsolateral
inferior parietal
cingulate gyrus
24
Q

Spelling impairment in dementia

25
Calculation brain area
prefrontal frontal dorsolateral left parietal cingulate gyrus
26
Calculation impairent in dementia
AD > FTD > VASC
27
Perseveration/inability to shift attention/tasks brain area
frontal lobe
28
perseveration/shifting attention/tasks impairment in dementia
FTD > AD
29
Naming brain area
L Temporal | Parietal
30
Naming impairment in dementia
VASC > AD > FTD
31
Repetition impairment brain area
Wernicke Broca Arcuate fasciculus
32
repetition impairment in dementia
VASC > AD > FTD
33
3-step command brain area
temporal frontal premotor
34
reading and comprehension brain area
L parietal | temporal
35
Writing brain area
L parietal
36
3-step command, reading/comprehension, writing impairment in dementia
variable
37
Copy design brain area
R parietal | Basal ganglia with projections to prefrontal cortex
38
Copy design impairment in dementia
DLB = DPD > VASC > AD> FTD | Vasc: visuospatial impairment > then delayed recall (2-3 min)
39
Abstract thinking brain area
frontal | prefrontal
40
Abstract thinking impairment in dmentia
FTD > AD
41
Trail making test A
R-sided lesions frontal parietal
42
Train making test B
L-sided lesions frontal parietal
43
Trail making test impairment in dementia
FTD > AD
44
verbal fluency brain area
frontal | prefrontal
45
verbal fluency impairment in dementia
FTD > AD
46
R-L orientation brain area
L parietal
47
R-L orientation impairment in dementia
VASC > AD
48
Clock drawing test
``` Comprehension: temporal Planning/sequencing/organizing: frontal Constructional ability: R-parietal Praxis: L parietal Visual processing: occipital ```
49
Clock drawing test impairment in dementia
AD > Vascular