Cognition/intellect Flashcards Preview

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Flashcards in Cognition/intellect Deck (49):
1

Visuospatial function

parietal lobe (R/L)
visuoconstruction
visuoperception
visuoorientation

2

Visuospatial function deficits

getting lost in familiar environments
visual distortions
agnosias
distortion: oscillopsia, macropsia

3

Executive function location

dorsolateral prefrontal cortex
posterior parietal lobe

4

Social cognition location

insular cortex
orbitofrontal cortex - response inhibition
anterior cingulate -drive, motivation

5

Dementia

impaired cognition
impaired function
not related to a medical condition/medication
decline from previous function
not related to learning disability

6

Examples of dementia

Alzheimer's
vascular
Lewy Body
Frontotemporal
Parkinson's disease
Huntington's

7

Neuropathology of dementia

misfolded proteins
Alzheimer's - beta amyloid
Parkinson's/lewy body

8

Selective vulnerability to dementia

certain protein aggregates have affinity to certain anatomic regions
Cell death/dysfunction in those regions
does not work 100% of the time
DDx for corticobasilar syndrome

9

Recall neuroanatomy

dorsolateral prefrontal cortex

10

Attention/working memory neuroanatomy

dorsolateral prefrontal cortex
posterior parietal lobe

11

Language neuroanatomy

Primary auditory cortex
Wernicke's
Broca's

12

Pentagon test neuroanatomy

parietal
visual cortex
inferior temporal lobes

13

3 step command test neuroanatomy

dorsolateral prefrontal cortex

14

MOCA

screening
more difficult
better at picking up mild cognitive impairment - 80% sensitivity

15

Orientation to time/place brain area

temporal
frontal

16

Orientation to time/place in dementia

impaired relatively late in course of dementia

17

Orientation to person brain area

SELF: medial prefrontal and posterior cingulate cortex
OTHERS: fusiform gyrus (occipitltemporal gyrus) in temporal lobe

18

Orientation to person in dementia

impaired very late

19

Immediate recall impairment brain area

Wernicke, Broca, Arcuate fasciculus

20

Immediate recall impairment in dementia

FTD > AD

21

Delayed recall (2-3 min) impairment brain area

Hippocampus
medial temporal lobe (high density of NFT, NP)

22

Delayed recall impairment in dementia

AD > FTD
AD --> rapid rate of forgetting for 10 minutes

23

Spelling brain area

prefrontal
frontal dorsolateral
inferior dorsolateral
inferior parietal
cingulate gyrus

24

Spelling impairment in dementia

AD > FTD

25

Calculation brain area

prefrontal
frontal dorsolateral
left parietal
cingulate gyrus

26

Calculation impairent in dementia

AD > FTD > VASC

27

Perseveration/inability to shift attention/tasks brain area

frontal lobe

28

perseveration/shifting attention/tasks impairment in dementia

FTD > AD

29

Naming brain area

L Temporal
Parietal

30

Naming impairment in dementia

VASC > AD > FTD

31

Repetition impairment brain area

Wernicke
Broca
Arcuate fasciculus

32

repetition impairment in dementia

VASC > AD > FTD

33

3-step command brain area

temporal
frontal
premotor

34

reading and comprehension brain area

L parietal
temporal

35

Writing brain area

L parietal

36

3-step command, reading/comprehension, writing impairment in dementia

variable

37

Copy design brain area

R parietal
Basal ganglia with projections to prefrontal cortex

38

Copy design impairment in dementia

DLB = DPD > VASC > AD> FTD
Vasc: visuospatial impairment > then delayed recall (2-3 min)

39

Abstract thinking brain area

frontal
prefrontal

40

Abstract thinking impairment in dmentia

FTD > AD

41

Trail making test A

R-sided lesions
frontal
parietal

42

Train making test B

L-sided lesions
frontal
parietal

43

Trail making test impairment in dementia

FTD > AD

44

verbal fluency brain area

frontal
prefrontal

45

verbal fluency impairment in dementia

FTD > AD

46

R-L orientation brain area

L parietal

47

R-L orientation impairment in dementia

VASC > AD

48

Clock drawing test

Comprehension: temporal
Planning/sequencing/organizing: frontal
Constructional ability: R-parietal
Praxis: L parietal
Visual processing: occipital

49

Clock drawing test impairment in dementia

AD > Vascular