Cognition/intellect Flashcards
(49 cards)
Visuospatial function
parietal lobe (R/L)
visuoconstruction
visuoperception
visuoorientation
Visuospatial function deficits
getting lost in familiar environments
visual distortions
agnosias
distortion: oscillopsia, macropsia
Executive function location
dorsolateral prefrontal cortex
posterior parietal lobe
Social cognition location
insular cortex
orbitofrontal cortex - response inhibition
anterior cingulate -drive, motivation
Dementia
impaired cognition impaired function not related to a medical condition/medication decline from previous function not related to learning disability
Examples of dementia
Alzheimer's vascular Lewy Body Frontotemporal Parkinson's disease Huntington's
Neuropathology of dementia
misfolded proteins
Alzheimer’s - beta amyloid
Parkinson’s/lewy body
Selective vulnerability to dementia
certain protein aggregates have affinity to certain anatomic regions
Cell death/dysfunction in those regions
does not work 100% of the time
DDx for corticobasilar syndrome
Recall neuroanatomy
dorsolateral prefrontal cortex
Attention/working memory neuroanatomy
dorsolateral prefrontal cortex
posterior parietal lobe
Language neuroanatomy
Primary auditory cortex
Wernicke’s
Broca’s
Pentagon test neuroanatomy
parietal
visual cortex
inferior temporal lobes
3 step command test neuroanatomy
dorsolateral prefrontal cortex
MOCA
screening
more difficult
better at picking up mild cognitive impairment - 80% sensitivity
Orientation to time/place brain area
temporal
frontal
Orientation to time/place in dementia
impaired relatively late in course of dementia
Orientation to person brain area
SELF: medial prefrontal and posterior cingulate cortex
OTHERS: fusiform gyrus (occipitltemporal gyrus) in temporal lobe
Orientation to person in dementia
impaired very late
Immediate recall impairment brain area
Wernicke, Broca, Arcuate fasciculus
Immediate recall impairment in dementia
FTD > AD
Delayed recall (2-3 min) impairment brain area
Hippocampus
medial temporal lobe (high density of NFT, NP)
Delayed recall impairment in dementia
AD > FTD
AD –> rapid rate of forgetting for 10 minutes
Spelling brain area
prefrontal frontal dorsolateral inferior dorsolateral inferior parietal cingulate gyrus
Spelling impairment in dementia
AD > FTD