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C > Common medicines, DMARDs and Biologics > Flashcards

Common medicines, DMARDs and Biologics Flashcards

1
Q

What is used to treat atherosclerosis?

A

Statins

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2
Q

What is used to treat hypertension?

A 
B-blockers
Diurectics
ACE inhibitors
Angiotensin 2 antagonists
Calcium channel blockers
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3
Q

Examples of B-blockers

A

Bisoprolol

Atenalol

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4
Q

Example of diurectic

A

Bendroflumethiazide

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5
Q

Example of ACE inhibitor

A

Ramipril

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6
Q

Example of Angiotensin 2 antagonist

A

Valsartan

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7
Q

Example of Calcium Channel blocker

A

Amlodipine

Nifedipine

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8
Q

What is used to treat Ischaemic heart disease?

A 
Anti-platelets
Cholesterol / Statins 
B-blockers
Calcium channel blockers
Nitrates
Others / Nicorandil
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9
Q

Example of anti-platelet

A

Clopidogrel

Aspirin

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10
Q

Example of Nitrate

A

GTN

Isosrbide mononitrate

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11
Q

What is used to treat heart failure?

A

Diuretics
ACE inhibitors/ angiotensin 2 receptor antagonists
B-blockers
Digoxin

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12
Q

What is used to treat Valvular heart disease?

A

Anti-coagulants - warfarin, dipyridamole

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13
Q

What is used to treat Arrhythmias

A 
Anti-coagulants e.g. warfarin, rivaroxaban 
Calcium Antagonists 
Digoxin
Amiodarone 
B-blockers
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14
Q

What medications are associated with MRONJ?

A

Bisphosphonates
Denosumab
Anti-angiogenics

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15
Q

Asthma medication

A 
Short acting beta 2 antagonist 
Steroids
Long acting beta 2 antagonist 
Anti leukotrienes 
Systemic steroids
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16
Q

Example of short acting beta 2 antagonist

A

Salbutamol

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17
Q

Example of steroid inhalor (2)

A

Beclometasone

Fluticasone

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18
Q

Example of long acting beta 2 antagonist

A

Salmeterol

19
Q

Example of Anti-leukotienes

A

Montelukast

20
Q

Example of systemic steroids

A

Prednisolone

21
Q

What is used to treat COPD

A 
Short acting beta 2 antagonist
Short acting muscarinic antagonists
Long acting beta 2 antagonist
Long acting muscarinic antagonist 
Steroid inhaler 
Mucolytic 
Systemic steroids
Antibiotic
22
Q

Short acting beta 2 antagonist

A

Salbutamol

23
Q

Short acting muscarinic antagonist

A

Ipatropium

24
Q

Long acting beta 2 antagonist

A

Salmeterol

25
Q

Long acting muscarinic antagonist

A

Tiotropium

26
Q

Steroid inhaler

A

Fluticasone

Beclometasone

27
Q

Mucolytic

A

Carbocisteine

28
Q

Systemic steroid

A

Prednisolone

29
Q

Antibiotic

A

Azithromycin

30
Q

Management of autoimmune diseases

A 
Early diagnosis
Symptom control - pain
Corticosteroids 
DMARDs
Others - physiotherapy
31
Q

Possible side effects of corticosteroids?

A 
Cushing's syndrome
Osteoporosis prophylaxis
Candidosis
MRONJ
Prophylaxis
32
Q

What does DMARD stand for?

A

Disease modifying anti rheumatic drug

33
Q

List examples of DMARDs

A 
Methotrexate
Ciclosporin 
Hydroxychloroquine
Azathioprine
Mycophenolate mofetil 
Sulfasalazine
Gold (sodium aurothiomalate) 
Leflunomide
34
Q

How often is methotrexate taken?

A

Once per week

Orally or subcutaneous injection

35
Q

Side effects of methotrexate

A

Mouth ulcers, neutropenia, thrombocytopenia, abN LFTs, pneumonitis

36
Q

Which supplement may be required?

A

Folic acid

37
Q

Monoclonal antibody therapy is given to which group of PTs?

A

Those who have “failed” therapy with at least 2 DMARDs

38
Q

Examples of TNF alpha inhibitors

A 
Adalimumab 
Certolizumab
Etanercept
Infliximab
Golimumab
39
Q

Interleukin inhibitors

A

Tocilizumab

Ustekinumab

40
Q

T-cell activation inhibitors

A

Abtacept

41
Q

Anti-B lymphocyte

A

Rituximab

42
Q

Antineoplastic

A

Cetuximab

43
Q

What risk comes with taking monoclonal antibody therapy?

A

Double risk of serious infections for patients

Side effects - heart failure, lupus-like, demyelination, skin cancer, dental infections

C (7 decks)

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