Community-Acquired Pneumonia Flashcards

(49 cards)

1
Q

What are the causative organisms for Community-Acquired Pneumonia?

A

Rhinoviruses, Streptococcus pneumoniae, Mycoplasma pneumoniae, Legionella species, Histoplasma capsulatum, Pneumocystis jirovecii.

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2
Q

What form of Community-Acquired Pneumonia is Rhinoviruses?

A

Virus

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3
Q

What are the most common modes of transmission for Community-Acquired Pneumonia (Rhinoviruses)?

A

Droplet contact or endogenous transfer

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4
Q

What was the virulence factors for Community-Acquired Pneumonia (Rhinoviruses)?

A

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5
Q

How do you culture/diagnose for Community-Acquired Pneumonia (Rhinoviruses)?

A

Failure to find bacteria or fungi

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6
Q

How do you prevent Community-Acquired Pneumonia (Rhinoviruses)?

A

Hygiene

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7
Q

How do you treat Community-Acquired Pneumonia (Rhinoviruses)?

A

None

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8
Q

What are the distinctive features of Community-Acquired Pneumonia (Rhinoviruses)?

A

Usually mild

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9
Q

What are the epidemiological features of Community-Acquired Pneumonia (Rhinoviruses)?

A

9% of CAP cases

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10
Q

What form of Community-Acquired Pneumonia is Streptococcus pneumoniae?

A

Bacterial, gram-positive

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11
Q

What are the most common modes of transmission for Community-Acquired Pneumonia (Streptococcus pneumoniae)?

A

Droplet contact or endogenous transfer

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12
Q

What are the virulence factor for Community-Acquired Pneumonia (Streptococcus pneumoniae)?

A

Capsule

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13
Q

How do you culture/diagnose Community-Acquired Pneumonia (Streptococcus pneumoniae)?

A

Gram stain often diagnostic, alpha-hemolytic on blood agar

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14
Q

How do you prevent Community-Acquired Pneumonia (Streptococcus pneumoniae)?

A

PCV-13 or PPSV23 vaccine

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15
Q

How do you treat Community-Acquired Pneumonia (Streptococcus pneumoniae)?

A

Doxycycline, ceftriaxone, with or without vancomycin, much resistance

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16
Q

What are the distinctive features of Community-Acquired Pneumonia (Streptococcus pneumoniae)?

A

Patient usually severely ill

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17
Q

What are the epidemiological features of Community-Acquired Pneumonia (Streptococcus pneumoniae)?

A

5% of CAP cases; Drug-resistant strains in CDC Serious Threat category

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18
Q

What form of Community-Acquired Pneumonia is Mycoplasma pneumoniae?

A

Bacteria

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19
Q

What are the most common modes of transmission for Community-Acquired Pneumonia (Mycoplasma pneumoniae)?

A

Droplet contact

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20
Q

What are the virulence factors for Community-Acquired Pneumonia (Mycoplasma pneumoniae)?

21
Q

How do you culture/diagnose Community-Acquired Pneumonia (Mycoplasma pneumoniae)?

A

Rule out other etiologic agents; serology; PCR

22
Q

How do you prevent Community-Acquired Pneumonia (Mycoplasma pneumoniae)?

A

No vaccine, no permanent immunity

23
Q

How do you treat Community-Acquired Pneumonia (Mycoplasma pneumoniae)?

24
Q

What are distinctive features of Community-Acquired Pneumonia (Mycoplasma pneumoniae)?

A

Usually mild; “walking pneumonia”

25
What are the epidemiological features of Community-Acquired Pneumonia (Mycoplasma pneumoniae)?
---
26
What form of Community-Acquired Pneumonia is Legionella species?
Bacterial, gram-negative
27
What are the most common modes of transmission for Community-Acquired Pneumonia (Legionella species)?
Vehicle (water droplets)
28
What are the virulence factors for Community-Acquired Pneumonia (Legionella species)?
---
29
How do you culture/diagnose Community-Acquired Pneumonia (Legionella species)?
Urine antigen test; culture requires selective charcoal yeast extract agar
30
How do you prevent Community-Acquired Pneumonia (Legionella species)?
---
31
How do you treat Community-Acquired Pneumonia (Legionella species)?
Fluoroquinolone, azithromycin, clarithrromycin
32
What are the distinctive features for Community-Acquired Pneumonia (Legionella species)?
Mild pneumonias in healthy people; can be severe in elderly or immunocompromised
33
What are the epidemiological features of Community-Acquired Pneumonia (Legionella species)?
United States: on the rise; 6,000 to 8,000 cases annually
34
What form of Community-Acquired Pneumonia is Histoplasma capsulatum?
Fungi
35
What are the most common modes of transmission for Community-Acquired Pneumonia (Histoplasma capsulatum)?
Vehicle--inhalation of fungal spores in contaminated soil
36
What are the virulence factors for Community-Acquired Pneumonia (Histoplasma capsulatum)?
Survival in phagocytes
37
How do you culture/diagnose Community-Acquired Pneumonia (Histoplasma capsulatum)?
Rapid antigen tests, microscopy
38
How do you prevent Community-Acquired Pneumonia (Histoplasma capsulatum)?
Avoid soil contaminated with bird and bat droppings
39
How do you treat Community-Acquired Pneumonia (Histoplasma capsulatum)?
Itrraconazole
40
What are the distinctive features of Community-Acquired Pneumonia (Histoplasma capsulatum)?
Many infections asymptomatic
41
What are the epidemiological features of Community-Acquired Pneumonia (Histoplasma capsulatum)?
In United States: 250,000 infected per year; 5% to 10% have symptoms
42
What form of Community-Acquired Pneumonia is Pneumocystis jiroveci?
Fungus
43
What are the most common modes of transmission for Community-Acquired Pneumonia (Pneumocystis jirovecii)?
Vehicle--inhalation of fungal spores
44
What are the virulence factors for Community-Acquired Pneumonia (Pneumocystis jirovecii)?
---
45
How do you culture/diagnose Community-Acquired Pneumonia (Pneumocystis jirovecii)?
Microscopy
46
How do you prevent Community-Acquired Pneumonia (Pneumocystis jirovecii)?
Antibiotics given to AIDS patients to prevent this
47
How do you treat Community-Acquired Pneumonia (Pneumocystis jirovecii)?
Trimethoprim-sulfamethoxazole
48
What are the distinctive features of Community-Acquired Pneumonia (Pneumocystis jirovecii)?
Vast majority occur in AIDS patients
49
What are the epidemiological features of Community-Acquired Pneumonia (Pneumocystis jirovecii)?
Almost exclusively in severely immunocompromised patients