Conjunctiva, Cornea Flashcards

(41 cards)

1
Q

What block will help you with opening the eyelid of a horse?

A

Auriculopalpebral nerve block

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2
Q

What nerve block will give you anesthesia of the upper eyelid?

A

Frontal nerve block (branch of trigeminal) in the supraorbital foramen

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3
Q

What are the three common uses of a fluorescein stain?

A

Diagnosis and characterization of corneal ulceration
Demonstration of nasolacrimal patency
Demonstration of corneal perforation

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4
Q

What are the 5 layers of the cornea?

A

Pre corneal tear film
Corneal epithelium
Corneal stroma
Descemete’s membrane
Endothelium

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5
Q

What is the most sensitive structure in the mammalian body?

A

Cornea

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6
Q

What are dermoids?

A

Non progressive congenital lesions consisting of epithelial and dermis like components found in an abnormal location

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7
Q

Where do dermoids most frequently arise from?

A

Limbus

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8
Q

What is curative for dermoids?

A

Complete surgical excision

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9
Q

What breeds are megalocornea and cornea globosa (MCOA) seen in?

A

Rocky mountain horses
Coat color association - chocolate coats with white mane and tail

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10
Q

What do horses with megalocornea and cornea globosa have an increased risk for?

A

Corneal ulceration and exposure keratitis

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11
Q

What is eosinophilic keratoconjunctivitis?

A

Inflammatory disease of the cornea and conjunctiva
White raised plaques on the cornea and/or conjunctiva
Most cases are within the summer months

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12
Q

How would you diagnose eosinophilic keratoconjunctivitis?

A

Eosinophils on corneal cytology

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13
Q

How would you treat eosinophilic keratoconjunctivitis?

A

Oral steroids (dexamethasone)
Oral antihistamine (cetirizine)
Topical antibiotic - only if corneal ulceration is present

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14
Q

When would you do a follow up for eosinophilic keratoconjunctivitis? What is the average healing time?

A

Initial recheck in ~2 weeks, serial follow up monthly until resolved
Takes about 2.5 months to heal
1/3 recurrence rate

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15
Q

What is KCS most commonly associated with in horses?

A

Loss of parasympathetic nerve supply to lacrimal tissue (facial nerve)
Associated with trauma, mandibular fracture, stylohyoid fracture

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16
Q

How would you treat KCS supportively?

A

Topical tear stimulant (Tacrolimus or cyclosporine)
Topical tear replacement
Topical antibiotic if corneal ulcer

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17
Q

What is a simple corneal ulcer?

A

Superficial with no signs of infection or stromal loss

18
Q

How would you treat a simple corneal ulcer?

A

Topical antibiotic q 8 hr
Topical atropine sulfate 1% given once in clinic
Systemic NSAID q 12-24 hr
Topical antifungal q 6 hr (must be given 4x a day or they do not work)
Should be healed within 1-2 weeks

19
Q

What are the common causes of corneal ulcer infection (melting)?

A

Bacterial - staphylococcus, streptococcus, pseudomonas
Fungal - aspergillus

20
Q

What causes keratomalacia (melting ulcer)?

A

Secondary bacterial and/or fungal infection
Endogenous proteinases (neutrophils, corneal epithelial cells)
Previous topical corticosteroid administration

21
Q

How would you treat an infected corneal ulcer?

A

Topical atropine sulfate 1% q 8-24 hr
Topical antifungal (voriconazole 1%) q 2-6 hr
Topical antibiotic (moxifloxacin or another fluroquinolone) q 2-6 hr
Anti-melting medication (serum, EDTA 1%, topical tetracycline, N-acetylcystine) q 2-6 hr

22
Q

How long should you expect an infected ulcer take to heal?

A

Around 8 weeks

23
Q

When would you consider surgery in an infected corneal ulcer?

A

> 50% stromal depth
Rapidly progressive
Melting
No vascular response
Perforated

24
Q

What is a corneal stromal abscess?

A

Small puncture wound that seals, leaving infection and/or foreign bodies in cornea

25
Will there be fluorescein stain uptake in a corneal stromal abscess?
No
26
What are the treatment options for corneal stromal abscesses?
Medical management Surgical removal Intrastromal voriconazole injection Penetrating keratoplasty (full thickness resection of cornea) Posterior lamellar keratoplasty Deep lamellar endothelial keratoplasty Enucleation
27
What is an indolent corneal ulcer?
Corneal ulceration for duration longer than 1-2 weeks No signs of infection or other reasons for delayed healing More common in older horses
28
What is immune mediated keratitis?
Non ulcerative keratitis Corneal opacification Vascularization Usually minimal to no pain
29
How would you treat IMMK?
Topical NSAID q 8-24 hr Nepafenac or Bromfenac (Expensive) Topical steroids (increased risk for fungal keratitis with chronic use) Immunomodulators - effective for superficial form
30
What can IMMK progress to?
Lymphoma
31
What is a good surgical option for IMMK?
Cyclosporine implant Surgical removal
32
How would you treat EHV keratitis?
Topical antiviral (Cidofovir) Systemic NSAID
33
What does subepithelial keratomycosis look like clinically?
Epithelial IMMK Equine herpesvirus keratitis
34
What would make you think subepithelial keratomycosis?
Pain
35
How would you treat subepithelial keratomycosis?
Topical atropine sulfate Topical antifungal Topical antibiotic Systemic NSAID as needed
36
What is the most common ocular tumor?
Squamous cell carcinoma
37
Is recurrence common in SCC?
Yes
38
What are the risk factors for SCC?
Lack of pigment Increased age Breed predilection (Appy, Halfs, Drafts) UV radiation Chronic tissue inflammation/infection
39
What does a SCC typically look like?
Thickened to raised, vascularized conjunctiva/cornea with cobble stone texture
40
What is the hallmark of SCC on histopath?
Collagen pearls
41
What is the treatment for SCC?
Chemotherapy Surgery + adjunctive therapy