Connective Tissue Flashcards

(66 cards)

1
Q

the fluid component of blood

A

plasma

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2
Q

a tissue, the major constituent of which is extracellular matrix

A

connective tissue

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3
Q

osteoid matrix- over 90% collagen type 1 embedded in a ground substance of proteoglycans, condroitin, keratin, and hyaluronic acid. Mineralized with calcium phosphate as _______

A

hydroxyapatite

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4
Q

extracellular material between cartilage cells

A

chondroid matrix

or ground substance

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5
Q

polysaccharides formed or repeating disaccharide sub-units composed of ironic acid and hexosamine

A

glycosaminoglycans

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6
Q

a hexose with the primary hydroxyl group oxidized to form an acid

A

uronic acid

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7
Q

a hexose with an amino acid attached

A

hexosamine

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8
Q

in glycosaminoglycans, ironic acid, and hexosamine, ______ is the predominant molecular component

A

carbohydrate

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9
Q

protein core with many glucosaminoglycans attached

A

proteoglycan molecules

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10
Q

hyaluronic acid core with many proteoglycans attached

A

proteoglycan aggregates

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11
Q

most abundant protein in the human body

A

collagen

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12
Q

type of collagen that is most common, found in every connective tissue, forms tendons and ligaments

A

type I

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13
Q

type of collagen that is found only in hyaline and elastic cartilage and in the vitreous body of eye

A

type II

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14
Q

type of collagen that is found in reticular fibers, healing wounds, smooth muscle, fetal skin, support for cellular structure of some organs such as the liver and spleen.

A

Type III

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15
Q

type of collagen that is found in the basal lamina of epithelia

A

type IV (4)

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16
Q

type of collagen that is found in placental basal laminae, tendon, and muscle sheaths

A

type V

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17
Q

stained black by silver salts

A

agyrophillic

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18
Q
  • forms a network of fibers
  • type III collagen
  • stained black by silver salts
  • important in anchoring small blood vessels to surrounding tissue
  • in smooth muscle
A

reticular fibers

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19
Q
  • form broad, wavy diffuse stained bundles
  • bundles branch and fuse forming a network
  • yellow in living tissue
  • protein elastin makes it yellow and elastic
A

elastic fibers (thinner that collagen fibers in pics)

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20
Q
  • actively involved in secretion of extracellular matrix (ground substance) and in fiber formation, usually collagen
  • associated with most CT
  • involved in woud healing, if absent, wound will not heal
  • grow easily in tissue culture (too easily)
A

fibroblast

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21
Q

macrophages are derived from

A

monocytes

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22
Q
  • many are present in Loose CT
  • actively phagocytic
  • derived from monocytes
A

macrophages

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23
Q
  • form embryonic connective tissue cells
  • resemble fibroblasts, but smaller
  • along capillaries and called pericytes
A

mesenchymal cells

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24
Q
  • form 3 dimensional networks of cells that are in contact via long processes
  • may be phagocytic
  • precursonrs for blood stem cells
  • function in immune response
A
  • reticular cells
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25
wandering cells that contain basophilic granules composed of heparin (a sulfated glycosaminoglycan) as well as other pharmacological agents such as histamine. important in allergic reactions
mast cells
26
antibody producing B lymphocytes
plasma cells
27
two types of adipose cells and functions
white fat: unilocular adipose- lipid storage | brown fat: multilocular storage- heat production
28
white blood cells
leukocytes
29
the dominant protein component of hyaline cartilage is
collagen type 2
30
location of hyaline cartilage
trachea
31
the main cell type of the perichondrium is
fibroblasts
32
immature cartilage cells that are not yet stuck in the lacunae
chondroblasts | - secrete extracellular matrix
33
mature cartilage cell
chondrocyte
34
2 or 3 chondrocytes and lacunae together
isogenic group
35
cartilage that is blueish white in color
hyaline cartilage
36
cartilage that is yellow in color
elastic cartilage
37
elastic cartilage has a high concentration of what fibers
elastic fibers
38
does elastic cartilage calcify?
no
39
location of elastic cartilage
ears
40
does fibrocartilage have a perichondrium?
no
41
what is the main fiber in fibrocartilage
collagen type 1
42
location of fibrocartilage
intervertebral disk
43
growth due to the secretion of matrix into the interstitial regions between cells or groups of cells
interstitial growth
44
bone that originated from cartilage template
endochondral bone
45
bone formed without a cartilage template
membranous bone
46
shaft of a bone
diaphysis
47
ends of a long bone
epiphysis
48
area of growth on a long bone
metaphysis
49
outer layer of connective tissue that covers the bone, contains fibroblasts and a high concentration of collagen fibers
periosteum
50
collagen fibers originating in the periosteum, penetrate the calcified bone matrix and bond periosteum to bone
sharpey's fibers
51
lines the internal surface of bones, one cell thick, NOT 2 layers
endosteum
52
mature bone cells that synthesize and secrete the osteiod matrix that will calcify as the bones extracellular matrix
osteoblasts
53
mature bone cells, osteoblasts that have not become embedded in calcified bone matrix
osteocytes
54
act to reabsorb bone, remodeled constantly
osteoclasts
55
calcitonin does what in bone, where does it come from
inhibits action of osteoclasts - lowers Ca++ concentration in blood - thyroid
56
what causes the Ca++ concentration to raise in blood, causes osteoclasts to be more active, and where does it come from
- parathyroid hormone | - from parathyroid gland
57
as a strand of matrix (in bone) is invested with inorganic salts, it is called a
spicule
58
spicules fuse with one another and form
trabeculae
59
the secretion by osteoblasts is cyclic and results in layers of bone material called
lamellae - lamellar bone
60
most of the bones in the mammalian body are initially formed by
endochondral means
61
two other words for spongy bone
cancellous or trabecular
62
concentric sub laters surrounding longitudinal tunnels for blood vessels and nerves that are called the
haversian canals
63
radical tunnels called _____ ______ that connect the haversian canals with one another and with the bone marrow and periosteum regions
Volkman's canals
64
the ____ and _____ are tubes though witch blood vessels and nerves can pass within the compact bone
volkmans and haversian
65
when a layer of chondroblasts can lay down matrix at the outer edge of a mass of cartilage
appositional growth
66
intramembranous formation occurs mainly in the
bones of the skull, flat