Connective Tissue Flashcards
(24 cards)
2 Types of Connective Tissue Proper
- Loose
- Dense
4 Types of Connective Tissue
- Connective tissue proper
- Cartilage
- Bone
- Blood
Loose Connective Tissue Prop.
large space between fibres filled with ECM
Dense Connective Tissue Proper
thick fibre networks containing high number of collagen, small ECM
2 Types of Dense Connective Tissue
- Regular
- Irregular
Regular Dense
- fibres arranged in same plane
- typically found in tendons and ligaments to resist forces in opposite directions
Irregular Dense
- arranged in random network
- typically found in joint capsules resist impact in many directions
3 Components of ECM
- Amorphous Ground Substance
- Protein Fibers (Collagen, Elastic, Reticular)
- Tissue Fluid
Amorphous Ground Substance
- contains glycoproteins, proteoglycans, glycosaminoglycans, water
- all substances entering/leaving cell must pass through
Type I Collagen
most abundant, found in bones, tendons, connective tissue proper, ligaments, fibrocartilage
Type II Collagen
hyaline and elastic cartilage, very thin fibrils
Type III Collagen
reticular fibres, often associated with type I
Elastic Fibers
can be stretched to 150% original length without damage
Connective Tissue Cell Classification
- Fixed Cells
- Transient Cells
Fixed Cells
- perform their function and remain in place within the connective tissue
- Fibroblasts, Adipose, Mast Cells
Transient Cells
- originate in bone marrow and circulate bloodstream to perform functions
- Macrophage, Plasma Cells
Fibroblasts
- most common cell in connective tissue
- synthesize collagen, reticular and elastic fibres and ground substances in ECM
- fibrocyte when mature
Adipose Cells
squished nucleus and store fat
2 Types of Adipose Cells
- White
- Brown
White Adipose
formed by uniocular fat cells (single large droplet)
Brown Adipose
formed by multiocular fat cells (small multiple droplets allowing storage of more fat)
Mast Cells
- can also be transient
- largest fixed cells, contain granules of histamine and heparin important for allergic reactions
Macrophages
originate from monocytes
Plasma Cells
- scattered throughout connective tissue
- found in areas with inflammation where they act to secrete antibodies