Connective Tissue Flashcards
(24 cards)
Soft ground substance
GAGs (glycosaminoglycans) hyaluronic acid in synovial fluid
Firm ground substance
GAGs (glycosaminoglycans) chondroitin sulphate in bone ground substance
Fixed cells
Cells that reside in the connective tissue where they perform their function
Fibroblasts, adipose cells, mast cells
Transient cells
Free wandering cells derived from bone marrow, circulate in bloodstream then migrate to the connective tissue to perform their function
Plasma cells, lymphocytes, neutrophils, macrophages
Fibroblast active
Close to collagen bundles
Stain dark, large and oval nucleus shape
Produce collagen, elastic fibres and reticular
Fibroblast inactive
smaller and oval shaped cell body compared to active
Nucleus is smaller and longer
Produce collagen, elastic fibres and reticular
Adipocytes
synthesis and storage of triglycerides
White adipose tissue
Store one large lipid droplet
Stain white
Brown adipose tissue
Store many small lipid droplets
Stain darker
Many mitochondria in close proximity for oxidising and production of heat
Macrophages
Transient cell Stem cells in bone marrow Monocytes in blood Macrophages in tissue Perform phagocytosis
Mast cells
Fixed cell
Stem cells in bone marrow
Filled with granolas for inflammatory response
Produce heparin and histamine
Plasma cells
Transient cell
Bone marrow -> B lymphocytes
Produce antibodies
Located mostly in inflammatory areas
Type I Collagen
Present in proper connective tissue (Fibrocartilage)
Chondrocytes parallel to collagen bundles
Perichondrium absent
Intervertebral discs, articular discs, pubic symphysis
Type III Collagen
Reticular fibres
Blood vessels, lungs, liver
Type II Collagen
Elastic (auditory canal) and hyaline cartilage (nose, larynx, trachea)
Type IV Collagen
Forms mesh of pro-collagen
Forms basement membrane
Type V Collagen
Associated with type I
Type VII Collagen
Anchoring fibres
Secure basement membrane to underlying connective tissue
Elastic fibres
Elastic property
Produced by smooth muscle cells in arteries and fibroblasts in connective tissue
Made of elastin
Blood vessels, skin, cartilage, lung , bladder
Reticular fibres
Type III collagen
Produced by fibroblasts, smooth muscle cells, reticular cells
Form framework of liver, spleen and smooth muscle
Connective tissue proper
Loose (areolar)
Dense (regular and irregular)
Reticular
Adipose
Loose connective tissue
Areolar connective tissue
Contains many transit cells for immune response
Dense regular connective tissue
Collagen in organised structure
Little ground substance and fibroblasts
Ligaments and tendons
Dense irregular connective tissue
collagen arranged randomly
In sheath of nerves and dermis of skin
