Connective Tissues 2 Flashcards
(23 cards)
Connective tissue types
1.free cells
2.fixed cells
Free cell types
1.plasma cells
2.mast cells
3.macrophage
4.leukocytes
Fixed cells types
1.mesenchymal cells
2.fibroblasts
3.fat cells
Mesenchymal cells (fixed cells)
(Mom of the group) structure
Branched cells
Pale basophilic cytoplasm
Mesenchymal cells function
Give rise to any other type of connective tissue cells
Stem cells
Fibroblast structure under light microscope
*young cells: branched with basophilic cytoplasm AND oval pale nucleus with prominent nucleolus
*old fibroblasts: flat, little pale acidophilic cytoplasm, flat or oval nucleus and prominent nucleolus
Fibroblast organelles (secretory cell)
RER
Golgi apparatus
Ribosomes
Mitochondria
Transfer and secretory vesicles
Fibroblast function
*formation of intercellular substances
1. Secrete tropocollagen (collagen fibers)
2.secretion of mucopolysacharide of the matrix
3. Secretion of elastin
4. Repair wounds
Fat cells structure
Stain: H&E stain
Appear as empty spaces + peripheral nucleus +thin rim of cytoplasm (signet ring)
Staining the fat: sudan black and osmic acid
Appears black
Fat cells origin
Fibroblasts
Mesenchymal cells
Plasma cells origin
B lymphocytes enter loose CT from the blood stream
Plasma cells structure
Spherical when free
Angular when compressed
Nucleus is eccentric with clock face heterochromatin
Cytoplasm is basophilic with pale are around the nucleus
Plasma calls organelles
RER
Free ribosomes
Golgi apparatus and a pair of centrioles
Mitochondria and secretory vesicles
Russell bodies
Plasma cell function
Secretion of antibodies
Mast cells origin
From bone marrow
Mast cells structure
Round or oval shape
Round central nucleus
Basophilic granules in the cytoplasm
Stain: toluidine blue (basic stain) metachromatic
Mast cells organelles
RER
Golgi
Mitochondria
Granules
Irregular outline
Mast cells function
Secrete histamine + heparin and chemical mediators
Macrophage origin
Mesenchymal cells in prenatal life
Come from loose CT from the blood in postnatal life
Macrophage structure
Oval shape when free
Elongated or angular when compressed
Irregular surface
Eccentric condensed indented nucleus
Macrophage stain
Trypan blue
Macrophage organelles EM
Phagocytose particles (phagosome)
Residual bodies
Multivesicular bodies
Lysosomes
Prominent golgi
RER
Macrophage function
Phagocytosis
