cop Flashcards
(10 cards)
What happens to primordial follicles at puberty?
At puberty, primordial follicles begin to develop further and become primary follicles.
What is the structure of an early primary follicle?
Contains a primary oocyte (2n) at its center, with the zona pellucida (transparent zone) beginning to appear and simple cuboidal epithelium surrounding it.
What is the zona pellucida and what is its function?
The zona pellucida is a glycoprotein coat secreted by the oocyte, playing a key role in fertilization and protection.
What types of cells surround the primary oocyte in a primary follicle?
The primary follicle consists of simple cuboidal follicular cells, basal lamina, and stromal cells.
What clinical implication arises from a defective zona pellucida?
A defective zona pellucida can lead to no fertilization by sperm, resulting in infertility.
What is the structure of the late primary follicle and what is special about it?
Structure: Primary oocyte (2n) in the center, Zona Pellucida
Stratified cuboidal epithelium.
Special: Follicular cells become granulosa cells (zona granulosa)
Stromal cells become: Theca cells or Theca folliculi cells
Q: What characterizes a secondary follicle and what is special about it?
contains a secondary oocyte (n) arrested in metaphase of meiosis II and is pushed off-center by antrum fluid.
Special: Antrum first appears
Q: What is a Graafian follicle and what special structures appear?
A Graafian follicle is a mature ovarian follicle containing a secondary oocyte (n) that is eccentric in position and arrested in metaphase II of meiosis.
Special:
Granulosa cells form the Corona radiata and Cumulus Oophorus
What is the id of each follicle and what is special about each one?
Primordial follicle simple squamous cells with no Antrum
Early primary follicle simple cuboidal cells with no Antrum (zona pellicuda first appears)
late primary follicle stratified cuboidal epithelium with no antrum (follicular cells become granulosa cells and stromal cells become theca cells)
Secondary follicle stratified cuboidal epithelium with a small Antrum
Mature follicle stratified cuboidal epithelium with a large Antrum (With Corona radiata and Cumulus Oophorus)
Corpus leutum: Big cavity with no oocyte
Corpus albicans White lines with big pink
What are the components of the blood-ovum barier?
Components of the Barrier:
Theca Interna Cells: These endothelial cells provide vascular support, ensuring a supply of blood and nutrients.
Granulosa Cells: Providing the next layer within the follicle, these cells are essential for hormone production and contribute to the barrier’s overall integrity.
Avascular Environment: The area surrounding the ovum is avascular, meaning there are no blood vessels directly supplying it, which further protects the ovum from potential immunological attacks or unwanted substances in the bloodstream.
