[COPD] Flashcards

(69 cards)

1
Q
A

80

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2
Q
A

0.7

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3
Q
A

the % of FVC which is expired in 1 second at maximum expiration

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4
Q
A

>=0.8

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5
Q
A

Reduced due to reduced air escaping

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6
Q
A

Normal (or increased)

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7
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A

in restrictive there is an equal reduction of FVC and FEV1 due to lung pathology. Sometimes the FEV1 may even be raised due to decreased compliance.

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8
Q
A

cough + sputum production for most days for 3 months of 2 consecutive years

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9
Q
A

cough + sputum production for most days for 3 months of 2 consecutive years

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10
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A

enlarged air spaces distal to terminal bronchioles + destruction of alveolar walls

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11
Q
A

enlarged air spaces distal to terminal bronchioles + destruction of alveolar walls

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12
Q
A

Pink puffer Blue bloater

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13
Q
A

increased

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14
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A

decreased

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15
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A

Pink puffer

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16
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A

Blue bloater

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17
Q
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high

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18
Q
A

low

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19
Q
A

normal or low

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20
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A

near normal

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21
Q
A

the hypoxic drive

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22
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A

CO2 (relatively)

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23
Q
A

Type 1 respiratory failure

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24
Q
A

cor pulmonale

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25
[COPD]: why is giving oxygen to a blue bloater potentially dangerous
deprives them of their hypoxic drive leading to extreme hypercapnia
26
[COPD]: why is giving oxygen to a blue bloater potentially dangerous
deprives them of their hypoxic drive leading to extreme hypercapnia/acid base imbalance
27
[COPD]: give 4 symptoms of COPD
cough sputum wheeze dyspnoea (SOB)
28
[COPD]: give 5 signs of COPD
accessory muscles Tachypnoea hyperinflation (cricosternal distance\<3cm) resonant/hyperresonant cor pulmonale
29
[COPD]: give 5 signs of COPD
accessory muscles Tachypnoea hyperinflation (cricosternal distance
30
[COPD]: give 3 complications of COPD
polycythaemia Cor pulmonale pneumothorax
31
[COPD]: what can cause a pneumothorax in the context of COPD
ruptured bullae (thin walled sac of air)
32
[COPD]: what causes polycythaemia
increased EPO due to 2ry hypoxia
33
[COPD]: what is cor pulmonale
right heart failure
34
[COPD]: what causes cor pulmonale
chronic pulmonary arterial hypertension
35
[COPD]: what would be noticed on the central pulmonary arteries
enlarged
36
[COPD]: give 2 signs of hyperinflation
flat hemidiaphragms \>6 anterior ribs seen above diaphragm in mid-clavicular line (assess adequacy of inspiration)
37
[COPD]: what is this x-ray showing
normal inflation - anterior end of 7th rib above diaphragm (less than 6 = impaired expansion; \>7 suggest hyperinflation)
38
[COPD]: right atrial and ventricular hypertrophy is indicative of ...
cor pulmonale
39
[COPD]: what would lung function tests show? (2)
FEV1 \<80% of predicted FEV1:FVC \<70% (0.7)
40
[COPD]: What is the cause of 'barrel chest' (large front to back diameter)
Hyperinflation
41
[COPD]: on Ix what would be seen in relation to TLC
increased TLC
42
[COPD]: what does DLCO stand for
diffusing capacity of the lung for carbon monoxide
43
[COPD]: there is reduced DLCO in which COPD disease
emphysema
44
[COPD]: what does DLCO measure
the extent to which O2 diffuse from the alveoli in to the RBCs
45
[COPD]: which disease can cause and increase in DLCO
polycythaemia
46
[COPD]: Tx: what lifestyle advice should you give
smoking cessation exercise
47
[COPD]: Tx: when is long term O2 therapy indicated (LTOT)
if PaO2 is \<7.3kPa
48
[COPD]: Tx: what is 1st line drug Tx for with COPD less severe than 'mild' severity (2)
Salbutumol OR Ipatropium (short acting) (as needed)
49
[COPD]: Tx: what is 1st line Tx for 'mild/moderate' COPD (2)
Tiotropium (long acting) or Salbutumol
50
[COPD]: Tx: what is the Tx options for severe COPD (30-49% of FEV1) (3)
Salbutumol + corticosteroid (i.e. symbicort) OR Tiotropium
51
[COPD]: Tx: what are the treatment options for severe COPD sufferers who are unresponsive to the appropriate Tx?
Tiotropium + salbutumol + corticosteroid
52
[COPD]: Tx: what is is contained in the compound drug symbicort (2)
budesonide + Formoterol (long acting)
53
[COPD]: Tx: at what stage should you refer to a specialist?
Symptomatic after adminstration of 'severe' stage drugs
54
[COPD]: Tx: how does tiotrpoiuum work
M3 antimuscarinic - long acting smooth muscle relaxation
55
[COPD]: Tx: how does salbutumol work?
short acting B2 adrenergic agonist causing smooth muscle relaxation
56
[COPD]: Dx: define Stage 1 'general' COPD
FEV1 \>=80%
57
[COPD]: Dx: define stage 2 'mild/moderate' COPD
FEV1 50-79% of predicted
58
[COPD]: Dx: define stage 3 'severe' COPD
FEV1 30-49% of predicted
59
[COPD]: Tx: what is 'steroid responsive COPD'
2 week trial of prednisolone FEV1 rises by \>15% long-term steroid may be helpful
60
[COPD]: Tx: what is the cut off for LTOT in stable non-smokers
\<7.3 kPa
61
[COPD]: Tx: what are the criteria for delivering LTOT at a kPa of 7.3-8.0 O2? (4)
pulmonary hypertension (loud s2/LVH) Polycythaemia peripheral oedema nocturnal hypoxia
62
[COPD]: Ix: what would you expect on an ABG
low PA02 hypercapnic
63
[COPD]: Tx: what are the 2 indications for surgery
recurrent pneumothoraces isolated bullae
64
[COPD]: What are bullae and how are they caused (2)
air filled sac one way valve (compressive effects)
65
[COPD]: what disease is associated with pink puffers
emphysema (damagaged alveoli walls + reduced blood flow)
66
[COPD]: what disease is associated with blue bloaters
chronic bronchitis (increased mucus production = obstructed airways = reduced ventilation)
67
[COPD]: what is the role of pulmonary surfacant (2)
reduces water surface tension increased lung compliance
68
[COPD]: Dx: define stage 4 'very severe' COPD
FEV1 \<30% of predicted
69
[COPD]: LTOT is given if the patients meets the criteria twice, ... weeks apart
\>3