[fungus infection] Flashcards
(58 cards)
1
Q
A
Aspergillus
Candida
Cryptococcus
2
Q
A
immunosuppressed
3
Q
A
candida
cryptococcus
4
Q
A
EAA - extrinsic allergic alveolitis
Asthma
Allergic bronchopulmonary aspergillosis
5
Q
A
EAA to aspergillus clavatus
6
Q
A
type 1 hypersensitivity
7
Q
A
IgE - x-link with mast cells
8
Q
A
immediate
9
Q
A
IgM or IgG - antibody mediated
10
Q
A
EAA - extrinsic allergic alveolitis Asthma Allergic bronchopulmonary aspergillosis invasive apergillosis aspergilloma
11
Q
A
IgM or IgG - antibody mediated
12
Q
A
f
13
Q
A
a pre-existing cavity
14
Q
A
TB
Sarcoidosis
15
Q
A
cough
haemoptysis
lethargy
weight loss
16
Q
A
CXR
17
Q
A
round opacity within cavity
18
Q
A
an antibody that precipitates out of the solution upon antigen binding
19
Q
A
aspergillosis
20
Q
A
Skin test
serum precipitans
sputum culture
21
Q
A
Skin test
serum precipitans
sputum culture
22
Q
A
infection
infarction
malignancy
23
Q
A
aspergillus
24
Q
A
infection
infarction
malignancy
25
[fungi]: what investigation can be used in invasive aspergillosis
Galactomannan
| an aspergillus antigen
26
[fungi]: what occurs in invasive aspergillosis
failure of body to mount an immune response
| invasion of aspergillus into blood stream --> organs
27
[fungi]: what occurs in invasive aspergillosis
failure of body to mount an immune response
| invasion of aspergillus into blood stream --> organs
28
[fungi]: what is the Tx for an aspergilloma
surgical excision
29
[fungi]: when would you Tx an aspergilloma
symptomatic
30
[fungi]: name 5 people who would be at increased risk of invasive aspergillus
```
HIV
broad spectrum Abx
SLE
Burns
Leukaemia
```
31
[fungi]: name 5 people who would be at increased risk of invasive aspergillus (5)
```
HIV
broad spectrum Abx
SLE
Burns
Leukaemia
```
32
[fungi]: what 2 types of hypersensitivity reaction occur in allergic bronchopulmonary aspergillosis (2)
type 1
| type 3
33
[fungi]: what is a type 3 hypersensitivity reaction mediated by
IgG - immune complex
34
[fungi]: which 2 groups of people may develop ABPA (2)
cystic fibrosis
| asthma
35
[fungi]: what impact does the type 1 hypersensitivity reaction have in ABPA
bronchoconstriction
36
[fungi]: what impact does the type 3 hypersensitivity reaction have in ABPA
immune complex deposition causing bronchiectasis
37
[fungi]: what may be found in the mucus of a person suffering from ABPA
fungal hyphae
38
[fungi]: what are fungal hyphae
filamentous structure of a fungus (made up of multiple hypha cells)
39
[fungi]: what are fungal hyphae
filamentous structure of a fungus (made up of multiple hypha cells)
40
[fungi]: a patient suffering from recurrent attacks of pneumonia may be suffering from which fungal infection
Allergic bronchopulmonary aspergillosis
41
[fungi]: describe the pattern of disease progression in ABPA
bronchoconstriction --> fibrosis --> proximal bronchiectasis --> mucoid impaction and lobar collapse
42
[fungi]: describe the pattern of disease progression in ABPA (4)
bronchoconstriction --> fibrosis --> proximal bronchiectasis --> mucoid impaction and lobar collapse
43
[fungi]: describe the pattern of disease progression in ABPA (4)
bronchoconstriction --> fibrosis --> proximal bronchiectasis --> mucoid impaction and lobar collapse
44
[fungi]: give 5 symptoms the patient may present with in ABPA
```
recurrent pneumonia
cough
sputum
dyspnoea
wheeze
```
45
[fungi]: give 5 symptoms the patient may present with in ABPA (5)
```
recurrent pneumonia
cough
sputum
dyspnoea
wheeze
```
46
[fungi]: what is the 1st line Ix for ABPA
CXR
47
[fungi]: what would be seen on CXR in ABPA (3)
consolidation
transient segmental collapse
bronchiectasis
48
[fungi]: what is consolidation
normally air filled tissue filled with liquid/tissue
49
[fungi]: What does RAST stand for (Ix)
radioallergosorbent test
50
[fungi]: what does a RAST test test for
determine substances a patient is allergic to
| via a blood test (cf. skin allergic test)
51
[fungi]: what Ig does a RAST implement
IgE
52
[fungi]: what Ig does a RAST implement
IgE
53
[fungi]: how are the 2 parts of a ABPA attack Mx?
Bronchodilators
| Prednisolone
54
[fungi]: how are the 2 parts of a ABPA attack Mx?
Bronchodilators
| Prednisolone 30-40mg/24hrs
55
[fungi]: what would noticed in relation to the eosinophil count in ABPA
eosinophilia
56
[fungi]: what would noticed in relation to the eosinophil count in ABPA
eosinophilia
57
[fungi]: amphotericin B is an anti-fungal drug - what must you do before administration of therapeutic doses
test dose - 1mg in 20 mL to observe for anaphylaxis (SE)
58
[fungi]: amphotericin B is an anti-fungal drug - what must you do before administration of therapeutic doses
test dose - 1mg in 20 mL to observe for anaphylaxis (SE)
