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Label
What is cushing’s syndrome?
Hypercortisolisim
Tumors (pituitary or adrenal)
iatrogenic (physician caused)
What is addisons disease?
Hypocortisolism
What are the causes and types of cushing’s syndrome?
Excessive Endogenous Cortisol
- ACTH independent: cortical tumor
- ACTH dependent: pituitary adenoma
small cell carcinoma
. Administration of Glucocorticoids
- The most common cause
· Clinical Manifestations
- weight gain, truncal obesity and moon face
- muscle weakness, thin arms and legs
- hypertension and osteoprosis
- moodiness, irritability, or depression
What are common clinical symptoms of addisons disease?
Bronze pigmentation of skin
Hypoglycemia
Changes in distribution of body hair
postural hypotension
weakness
Gi distrubances
What is conn’s syndrome?
Solitary aldosterone producing adenoma
Excess prodcution of aldosterone
it Causes: hypertension
Hypokalemia
What does the adrenal medulla produce?
Sympathetic stimulation
Catecholamine release to blood
Epinephrine
Norepinephrine
What is pheochromocytoma?
Tumor of the medulla of the adrenal gland