Core Microbiology - Drug Questions Flashcards Preview

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Flashcards in Core Microbiology - Drug Questions Deck (49):
1

Benzypenicillin, amoxicillin, flucloxacillin

Penicillins (cell wall synthesis inhibitors)

2

Cefuroxime, ceftazidime

Cephalosporins (cell wall synthesis inhibitors)

3

Meropenem, imipenem

Carbapenems (cell wall synthesis inhibitors)

4

Monobactams

Aztreonam (gram -ve activity only) (cell wall synthesis inhibitors)

5

Vancomycin and teicoplanin

Glycopeptides (cell wall synthesis inhibitors)

6

Gentamicin, amikacin

Aminoglycosides (protein synthesis inhibitors)

7

erythromycin and clarithromycin

Macrolides (protein synthesis inhibitors)

8

Clindamycin

Lincosamide (protein synthesis inhibitors)

9

Tetracycline, doxytetracycline

Tetracyline (protein synthesis inhibitors)

10

Linezolid

Oxazolidinones (protein synthesis inhibitors)

11

Trimethoprim

Trimethoprim(DNA Synthesis inhibitor)

12

Nalidixic acid, ciprofloaxcin, levofloxacin

Quinolone and Fluiroquinoles (DNA Synthesis inhibitor)

13

Rifampicin

RNA Polymerase/synthesis inhibitor

14

Colisitn

Gram -ve Plasma membrane agents

15

Daptomycin

Gram +ve plasma membrane agents

16

Treatment of S. aureus (not MRSA)

Flucloxacillin

17

Treatment of Strep pyogenes

Benzylpenicillin

18

Treatment of gram -ve bacilli

Cephalosporins (avoid in elderly)

19

Treatment of anaerobes

Metronidazole

20

Treatment of gram positives (MRSA)

Vancomycin

21

Treatment of most clinically relevant bacteria

meropenem

22

Last line treatment for multi-resistant gram -ves

Colistin

23

What is pseudomonas resistant to

ceftazidime and cerbapenems

24

what is MDR-TB

Multi drug resistant TB
Also have Extremely drug resistant (XDR-TB)

25

What do we use to treat MRSA if resistant

Linezolid as opposed to flucoxacillin

26

Last line treatment for enterbactericaea

Meropenem as opposed to ciprofloxacin

27

AZT

Azidothymidine
Anti cancer drug that inhibits HIV
Reverse transcriptase inhibitor

28

Zidovudine

Thymine analogue

29

Lamivudine

Cytosine analogue

30

Abacavir

Adenine analogue

31

Tenofovir

Guanine analogue

32

Efavirenz and neviropine

NNRTIs

33

Atanzavir and ritonavir

Protease Inhibitors

34

Enfuvirtide

Fusion inhibitor

35

Raltegravir

Integrates , doesn't cause toxicity

36

Maraviroc

Chemokine receptor agonises, helps treat HIV

37

Hep C treatment

Interferons and ribavarin

38

Acivlovir treats

HSC and VZV
It is a nucleoside analogue (phosphorylated by herpes virus thymidine kinase)

39

Ganciclovir treats

Cytomegalovirus

40

Oseltamavir and zanamavir

Neuraminidase inhibitors treat influenze

41

Ribavarin treas

Hep C and RSV

42

Interferons treat

Hep B/C

43

Polyenes

Nyastin and amphotericin B

44

Terbinafine

Allyamine

45

Clotrimazole

Imidazole

46

Fluconazole, itraconazole, voricaonazole

Triazole

47

Andilafungin

Echinocandin

48

5-fluorocytosine

synthetic cytosine anaologue

49

Griseofulvin

Inhibits fungal mitosis