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Cornea/External > Cornea 2 > Flashcards

Cornea 2 Flashcards

1
Q

Senile furrow degeneration

A

Appearance of thinning peripheral cornea in clear space between arcus and limbus. Not usually actual thinning. Totally benign.

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2
Q

Corneal farinata

A

suble dot-shaped and comma shaped opacities within the deep stroma that are age related (possible lipofuscin?) and have no clinical or visual significance.

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3
Q

What ELISA test can be performed to help in diagnosis of macular corneal dystrophy?

A

keratan sulfate

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4
Q

What are the types of hypolipoproteinemia syndromes that can results in corneal clouding?

A

LCAT (lecithin-cholesterol acyltransferase) deficiency
Tangier disease
Fish eye disease

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5
Q

Corneal dystrophies are AD EXCEPT which ones are AR?

A

Macular, Lattice type 3 only, gelatinous, and CHED2 (has nystagmus) are all AR!

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6
Q

What is the vision usually like in Meesman’s CD?

A

Good, all though tiny epithelial vesicles do affect the central cornea they are ususually not VS.

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7
Q

Reis-Bucklers’ and Thiel-Behnke’s is dystrophy of what layer of the cornea?

A

Bowmans

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8
Q

Central Cloudy (Francois) dystrophy is similar to what benign corneal finding?

A

Crocodile shagreen

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9
Q

Which corneal dystrophy has endothelium that behaves like epithelium forming multiple layers and occasional migration to the angle causing glaucoma? What other ocular disease is this dystrophy most similar to?

A

Posterior polymorphous; ICE syndrome

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10
Q

Fuchs superficial marginal keratitis is similar to what condition but happens in kids?

A

Terrien’s marginal degeneration

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11
Q

PTK can be used for pathology how deep?

A

Limited to 1/3 of stroma

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12
Q

What is the most common cause of mucin deficiency?

A

Vit A deficiency

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13
Q

What is characteristic of congenital stromal corneal dystrophy (CSCD)?

A

Diffuse clouding of the central cornea with whitish flakes

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14
Q

Alkaptonuria has what characteristic ocular surface finding?

A

pigmented conjunctiva at or near horizontal muscle insertions

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15
Q

Staph marginal infiltrates is what type of hypersensitivity reaction?

A

Type IV

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16
Q

Fleck corneal dystrophy has flecks in what part of the cornea?

A

stroma

17
Q

How thick is eyelid skin?

A

0.5mm near margin and 1mm at orbital rim

18
Q

How long does it take for cilia to grow back when cut? When pulled out?

A

2 weeks; 2 months

19
Q

What is a normal blink rate in adults?

A

15/min

20
Q

What is the horizontal and vertical diameters of the adult cornea?

A

11-12; 10-11

21
Q

What is the average radius of curvature of the adult cornea? What is the average dioptric power?

A

7.8; 43.25

22
Q

How thick is the average corneal epithelial layer?

A

50 microns

23
Q

What type of collagen is the corneal stroma composed of?

A

I, V, VI: 1+5=6

24
Q

What mechanisms help in maintaining the hydration status of the cornea?

A
  1. Active transport

2. Swelling pressure produced by negatively charged glucosaminoglycans

25
Q

What is a normal endothelial cell density?

A

2000-3000 cc/mm2

26
Q

What type of collagen is the sclera composed of?

A

Type 1 primarily

27
Q

What are 1. Basic secretion test; 2. Schirmer 1 test; 3. Schirmer 3 test? What are cut offs for abnormal?

A
  1. TOPICAL anesthetic followed by paper strip; less than 3mm is abnormal (5 min)
  2. No anesthetic followed by paper strip; less than 5.5 is abnormal (5 min)
  3. TOPICAL anesthetic followed by paper strip AND nasal irritation; less than 15 is abnormal (2 min)
28
Q

What amount of K edema starts to result in D-folds? Microcystic epithelial edema?

A

Greater than 10% thickness increase; over 700 microns

29
Q

What are the different zones of the cornea?

A
  1. Central zone: 1-2 mm
  2. Paracentral zone 3-4 mm from central zone
  3. Peripheral zone between paracentral and limbal
  4. Limbal zone

Cornea/External (3 decks)

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