Coronary Atherosclerotic Disease Flashcards
(47 cards)
coronary atherosclerotic disease is foundation for what?
chest pain and MI
what can feel like a heart attack?
bad acid reflux
angina is commonly seen in pts who do what drug?
crack cocaine
what is the founding cause of coronary atherosclerotic disease?
atherosclerosis
atherosclerosis
inflammation - plaque - stenosis
cause of atherosclerosis
exact cause unknown but is multifactorial
contributing factors of heart disease:
- hypertension
- type 2 diabetes
- abnormal blood lipid levels
- tobacco
- physical inactivity
- obesity
what is a significant contributing factor to heart disease?
hypertension
atherosclerotic disease starts out what?
asymptomatic but as plaque grows and stenosis worsens, will result in clinical symptoms (ischemic heart disease)
symptoms of coronary atherosclerotic disease
- oxygen demand > supply
- chest discomfort = ischemia
the most important symptom of someone that has had coronary atherosclerotic disease and #1 way to determine if treatable?
angina
stable angina
- precipitated by physical effort
- transient
how is stable angina relieved?
- rest
- nitroglycerin
what is the prognosis of stable angina?
good
unstable angina
- precipitated by effort or rest
- changing character
- difficult resolution
what is the prognosis of unstable angina?
poor
is stable angina reversible?
yes
when does stable angina occur?
when there is an increased demand on the heart
unstable angina may be associate with what?
heart attack
medical treatment of ischemic heart disease
- reduce risk factors
- treat contributing conditions
- lifestyle mods
- pharmacologic management
- revascularization
pharmacologic management of ischemic heart disease
- nitrates (nitroglycerin)
- beta blockers
- dual antiplatelet therapy
mechanism of nitrates
venodilator used for acute management of chest discomfort
mechanism of beta blockers
decrease risk of MI by decreasing HR and contractility
mechanism of antiplatelet therapy
make platelets less sticky so less likely to cause clots
dual anti-platelet therapy for managing ischemic heart disease
aspirin +/- clopidogrel