Corynebacterium diptheriae Flashcards

1
Q

Gram

A

Positivo

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2
Q

Forma

A

Son pleomórficos (Mazo, bastón)

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3
Q

Crea esporas?

A

sí, sólo en no diftéricas (espora en uno de sus extremos)

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4
Q

Colonizan?

A

Sí: Sólo no difteriae
- Piel
- Tracto digestivo
- Respiratorio
- Genitourinario

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5
Q

Cómo es la transmisión?

A

De humano a humano (sólo en difteria)

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6
Q

Toxina

A

Toxina diftérica (A-B)
- Parte A inhibe la síntesis de proteínas (EF2)

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7
Q

Enfermedades

A
  • Faringitis pseudomembranosa
  • Úlceras crónicas
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8
Q

Faringitis pseudomembranosa

A
  • Sangrado por el desprendimiento de membranas
    • 1-2 semanas después las toxinas causan miocarditis y neuropatías
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9
Q

Hay Vacuna?

A


- Vacuna toxoide: Se modifica la toxina para generar anticuerpos contra ella

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10
Q

Tratamiento

A
  • Antitoxina
  • Penicilina
    No se produce inmunidad
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