Histoplasmosis Flashcards

1
Q

Qué es?

A
  • Filamentoso en ambiente
  • Levadura en tejido
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2
Q

Tipos

A

H capsulatum
- var. capsulatum: Pumonar
- var. duboisii: Cutáneo y óseo

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3
Q

Endemicidad

A
  • EUA
  • México
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4
Q

En dónde se encuentra?

A

Suelos ricos en nitrógeno
- Excremento de murcélago y aves

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5
Q

Cómo se infecta?

A
  • Inhalación de aerosoles
  • Es intracelular
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6
Q

Enfermedades de var. capsulatum

A
  • Pseudogripal
  • Pulmonar crónica
  • Diseminada
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7
Q

Enfermedad pseudogripal

A

Asintomático el 90% de las personas
- 100% de ataque
- No necesita tratamiento

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8
Q

Enfermedad pulmonar crónica

A

Común en enfermedad pulmonar previa
- Cavidades apicales (como TB)
- Fibrosis

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9
Q

Enfermedad diseminada

A

Imunodeprimidos
Crónica
- Menos peso
- Fatiga
Subaguda
- Úlceras
- Hepatoesplenomegalia
- Médula ósea
Aguda (SIDA, trasplante)
- Shock séptico
- Meningitis
- Endocarditis (válvulas)

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10
Q

Diagnóstico

A
  • Microscopía: Giemsa, GMS, PAS
  • Cultivos de sangre y médula ósea
  • Serología: Histoplasmina
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11
Q

Tratamiento

A

1 a 2 años

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