CP

Question 1

cells can undergo regenration, what are the three main categories? give examples

Answer 1

labile - cells continue to proliferate throughout life.
eg skin, gut, mucosa, bone marrow

stable - cells turn over at low rate, can undergo rapid replication if needed
- eg kidney, liver, endocrine glands, bine

permanent - either incapable of mitotic division or organised proliferation
- eg cardiac muscle, neurones, straited/skeletal muscle

Question 2

which three tissue types can regenerate all constituents?

Answer 2

liver
bone
bone marrow

Question 3

define regeneration

Answer 3

the replacement of injured cells with the same type of cells

Question 4

define resolution

Answer 4

the complete return to normal structure and function after injury

Question 5

define restitution

Answer 5

return to normality due to a combination of regeneration and resolution

Question 6

define repair

Answer 6

the replacement of lost tissue by fibrous scar tissue

Question 7

which type of cell is does not undergo stable regeneration?

a) hepatocytes
b) renal cells
c) skeletal muscle cell
d) bone
e) endocrine glands

Answer 7

c) skeletal muscle cell - a form of permanent cell

Question 8

describe the four-step process of angiogenesis

Answer 8

• Enzymatic degradation of basement membrane f parent vessels
• Migration of endothelial cells towards stimulus
• Proliferation of endothelial cells into cords
• Maturation and lumen formation (initially leaky)