CR - OB/GYN Flashcards

(56 cards)

1
Q

What is the most common nonobstetric surgical emergency of pregnancy and how might it present in the 3rd trimester?

A

Appendicitis

The incidence of appendicitis in pregnancy is lower than in the general non-pregnant population of the same age. Though the incidence is not higher in pregnancy, complications occur more frequently because of delay in diagnosis.

In the 3rd trimester the appendix is displaced superiorly to the mid or upper right side of the abdomen

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2
Q

What is the most likely diagnosis of a 6 year old female presenting with malodorous, possibly bloody vaginal discharge?

A

Vaginal foreign body

  • children may insert anything
  • most common foreign body in prepubertal female is toilet paper
  • in adults, think about tampons, pessaries, diaphragms, condoms
  • treatment includes removing the object and treating for vaginitis
  • in children, suspect possible sexual abuse
  • may need to perform vaginoscopy under anesthesia for children
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3
Q

Describe the role of oral acyclovir in herpes simplex infections

A

Treating an acute infection with acyclovir decreases the duration of viral shedding of that specific outbreak, accelerates healing, and shortens the duration of symptoms but does not affect the frequency or severity of recurrence unless placed on prophylactic dosing.

HSV is a risk factor for cervical and vaginal cancer but has not been shown to be a cause. In pregnant women it is critical to treat genital HSV because neonatal infection can be contracted via passage through an infected birth canal and is associated with significant mortality (29%) and morbidity (primarily neurologic)

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4
Q

What is the most common etiology of dysuria in prepubertal females

A

Vulvovaginitis

the most common causes of acute vulvovaginitis include:
- infections - gardnerella vaginalis (most common), candida, trichomonas
- irritant or contact
- vaginal foreign body

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5
Q

What is the treatment for bacterial vaginosis (BV) and in what population is it essential to treat?

A

Metronidazole 500 mg PO BID for 7 days

  • BV is the most common cause of vulvovaginitis and is caused by a predominance of anaerobes in the vaginal microflora, BV often presents with complaints of malodorous fishy smelling discharge
  • BV should always be treated in pregnant women due to an increased incidence of premature rupture of membranes, preterm labor or delivery, and postpartum endometritis
  • alternative treatment regimens include clindamycin 300 mg PO BID or intravaginal clindamycin cream or metronidazole gel for 7 days. The CDC recommends either oral or intravaginal therapy for pregnant women.
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6
Q

What is the most commonly reported STI in the US that is also a leading cause of infertility

A

Chalmydia trachomatis

In addition to infertility, additional complications include chronic abdominal pain, Fitz-Hugh-Curtis syndrome and tubo-ovarian abscess.

7.3% of people with chlamydia are co-infected with gonorrhea

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7
Q

A 25 year old female presents with the sudden onset of lower abdominal pain and amenorrhea

What is your differential diagnosis?

A

Ruptured ectopic pregnancy
Hemorrhagic corpus luteum cyst

In the setting of amenorrhea, early ectopic pregnancy, ruptured ectopic pregnancy, and hemorrhage corpus luteal cyst are of primary concern.

However, always consider a broad differential in a female patient with acute pelvic pain, including PID, tubo-ovarian abscess, pyelonephritis, and appendicitis

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8
Q

How do you diagnose preeclampsia?

A

Preeclampsia: new onset of hypertension > 140/90 and proteinuria or new onset hypertension and end-organ dysfunction after 20 weeks gestation

End organ dysfunction:
- thrombocytopenic (less than 100,000)
- serum Cr > 1.1 or double normal concentration
- LFTs greater than 2x upper limit of normal
- pulmonary edema
- new onset headache unresponsive to medication or visual symptoms

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9
Q

What is the number one cause of fetal death, after maternal death, following blunt trauma to the mother?

A

Abruptio placentae

Defined as premature separation of a normally implanted placenta from the uterine wall causing visible or hidden bleeding, placental abruption is the cause of 30% of 3rd trimester bleeding

In addition to trauma, risk factors include HTN (most common), smoking, ETOH, cocaine, multiparity, advanced maternal age, prior abruption

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10
Q

A prolapsed umbilical cord is a true obstetrical emergency. What should the emergency physician due while awaiting arrival of the obstetrician?

A

The examiners hand should be used to elevate the presenting fetal part until a cesarean section can occur

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11
Q

In the 3rd trimester of pregnancy this antibiotic should not be used in the therapy of urinary tract infections?

A

Sulfonamides

Sulfonamides can cause kernicterus because of a rise in serum bilirubin

Prescribing sulfonamides or nitrofurantoin in the first trimester is still considered appropriate when no other suitable alternative antibiotics are available, but should be considered second line

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12
Q

What is the most common organism causing septic arthritis in patients less than 50 years old, particularly teenagers and young adults

A

Neisseria gonorrhoeae

  • most commonly a monoarticular infection involving knee, wrist, or elbow
  • joint effusion, warmth, and decreased range of motion are usually present
  • arthrocentesis will usually reveal > 50,000 WBC in synovial fluid
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13
Q

Which antibiotics should be avoided throughout pregnancy?

A

Tetracyclines, streptomycin, and kanamycin

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14
Q

What are the most common causes of vaginal bleeding for premenarchal girls, women in their reproductive years, and those after menopause?

A

Premenarche: trauma / foreign body, infeciton, anovulation

Reproductive years: normal menstrual cycle, pregnancy (intrauterine and ectopic)

Post menopause: atrophic vaginitis is most common, malignancy should be considered

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15
Q

What defines preeclampsia with severe features

A

Blood pressure > 160/110

Organ dysfunction
- new onset cerebral or visual dysfunction
- liver function test 2x greater than normal
- thrombocytopenia < 100K
- pulmonary edema
- serum creatinine > 1.1 or double normal concentration

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16
Q

How is candida vulvovaginitis treated?

A

Oral fluconazole 150 mg x 1 dose

May repeat dose in 72 hours if symptoms persist
Most common side effects are GI symptom, rash, and headache

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17
Q

What is a special population to be considered when using metronidazole

A

Nursing - instruct women to stop breastfeeding during and for 3 days after concluding metronidazole therapy

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18
Q

What is the treatment for a bartholin gland cyst or abscess?

A

Incision and drainage, followed by insert of word catheter or pediatric foley

Must be left in place for 4-6 weeks

consider antibiotics in special cases (recurrent abscess, MRSA, systemic infection

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19
Q

What is the most common cause of mortality in women with pelvic inflammatory disease

A

Ruptured tubo-ovarian abscess

Mortality is 5-10%

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20
Q

True or false: in patients with an IUD who are diagnosed with PID, the IUD should be removed

A

False

In cases of PID, the likely source of infection is an STI and not the device. The presence of a modern IUD does not put patients at higher risk of PID, and curent guide-lines do not support removal of the IUD

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21
Q

Does breastfeeding need to be stopped in cases of mastitis?

A

No, breastfeeding may continue

Key aspects of treatment are antibiotics and milk drainage

40% of cases are caused by staph aureus

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22
Q

What is the most common coagulation disorder associated with heavy uterine bleeding

A

Von-willebrand disease

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23
Q

What are the causes of dysfunctional uterine bleeding?

A

PALM COEIN

Structural:
- polyp
- adenomyosis
- leiomyoma
- malignancy

Non-structural:
- coagulopathy
- ovarian dysfunction
- endometrial
- iatrogenic
- not otherwise classified

24
Q

What is the most common location of ectopic pregnancy implantation?

A

Ampulla of the fallopian tube

25
What are the sonographic signs of an intrauterine pregnancy? When are they detectable?
Gestational sac: 5-5 weeks Yolk sac: 6.5 weeks - 1st definitive sign of intrauterine pregnancy Fetal pole: 7.0 weeks 1 week sooner for transvaginal
26
What is the discriminatory zone of beta-hCG level?
Beta hCG level at which ultrasound should confirm IUP 1,500 transvaginal 6,000 transabdominal Be aware that ectopic pregnancies can result in higher, normal, or lower than expected beta-hCG levels, and ruptured ectopic pregnancies have been reported at levels lower than 1000
27
When do you give RhoGAM and what is the dose?
Anytime there is mixing of fetal and maternal blood in an RH negative mother Prevents maternal alloimmunization, thereby preventing hemolytic disease of the newborn in future Rh positive pregnancies Dose: 300 mcg
28
What is the definition of a threatened abortion?
Vaginal bleeding during the first 20 weeks of pregnancy without cervical dilation
29
What is the definition of inevitable abortion?
Vaginal bleeding during pregnancy along with dilation of the cervical os
30
What is the definition of an incomplete abortion
Passage of some but not all products of conception
31
What is the definition of complete abortion
Passage of all fetal tissue before 20 weeks gestation
32
What is the definition of a missed abortion
Fetal death at <20 weeks without passage of any fetal tissue
33
What antibiotics should be used to cover infection caused by a septic abortion
Ampicillin or clindamycin 600mg Gentamicin 1-2 mg/kg IV Metronidazole 500 mg IV q8 hours Cover normal vaginal flora including gram positive, negative and anaerobes, and bacteria causing STI. Use clindamycin if toxin production is expected
34
What medications are used to treat hyperthyroidism in pregnancy?
Propylthiouracil (PTU): used exclusively in the first trimester. Can cause hepatotoxicity Methimazole Used during the second and third trimesters Rare side effects include agranulocytosis and aplastic anemia (must discontinue drug)
35
What classes of anti-hypertensives are contraindicated in pregnancy?
ACEI and ARBs (due to fetal renal injury) Commonly, hypertension in pregnancy is treated with labetalol, nifedipine, methyldopa, clonidine, or nifedipine. Thiazide diuretics can be continued in pregnancy
36
What anti-arrhythmic, that is commonly used for ventricular arrhythmias, is contraindicated in pregnancy?
Amiodarone Class D because its metabolites (desthylamiodarone and iodine) cross the placenta Iodine overload is associated with neurotoxicity, and fetal/neonatal hypothyroidism
37
Why is asymptomatic bacteriuria treated in pregnancy?
Treatment reduces the incidence of pyelonephritis, preterm birth, and low birth weight. TMP/SMX is contraindicated. TMP is a folate antagonist and can precipitate neural tube defects. SMX is a sulfonamide which can cause kernicterus
38
What percentage of ovarian torsion occurs in pregnancy?
Up to 20% Fertility treatment and corpus luteal cyst presence are risk factors. The presence of ovarian blood flow DOES NOT exclude the presence of torsion. It is a clinical diagnosis.
39
What are the first line maintenance antiepileptic drugs in pregnant women who have known seizure disorders?
Levetiracetam or lamotrigine Valproic acid, carbamazepine, and phenytoin are all teratogenic. Dosing may need to be increased during pregnancy.
40
What is the most devastating uterine emergency associated with cocaine use in pregnancy?
Placental abruption Also associated with IUGR, preterm labor, spontaneous abortion, and cerebral infarcts in the fetus
41
What is the leading cause of maternal morbidity and mortality in industrialized nations?
Venous thromboembolism 5 fold increased risk during pregnancy and 60 fold risk in first 3 months after delivery
42
What is the pathophysiology behind the increased risk for thromboembolic disease in pregnancy?
Increased levels of clotting factors, increased platelet and fibrin activation and decreased fibrinolysis Venous stasis due to gravid uterus and decreased outflow Mechanisms to prevent maternal hemorrhage
43
How do you treat VTE in pregnancy
Unfractionated heparin or LMWH (1 mg/kg BID) UFH is preferred in patients who are hemodynamically unstable, likely to bleed, who have renal insufficiency, and patients near delivery. Warfarin is contraindicated in almost all situations as it crosses the placental barrier Consult with obstetrics
44
In what situation can warfarin be used in pregnancy?
Women at high risk of thrombosis For example those with mechanical heart valves
45
What is the most common cause of heart failure in pregnancy
Peripartum cardiomyopathy: can occur at any stage of gestation A form of dilated cardiomyopathy Risk factors include prior cardiomyopathy, advanced maternal age, hypertension
46
What differentiates gestational hypertension from chronic hypertension in pregnancy?
Gestational hypertension is diagnosed after the 20th week of pregnancy Chronic hypertension is diagnosed before the 20th week of pregnancy and persists longer than 12 weeks after delivery
47
What is the dose of magnesium in eclampsia and HELLP syndrome?
4-6 grams given over 20-30 minutes Subsequent doses are 1-2 grams per hour for at least 24 hours after delivery. To assess for magnesium toxicity assess patellar reflexes and respiratory rate
48
What are the key laboratory abnormalities to identify HELLP syndrome
Hemolysis, Elevated Liver, Low Platelets - severe anemia (not attributable to blood loss) - low haptoglobin - elevated LDH - abnormal peripheral smear - hyperbilirubinemia - abnormal coagulation - elevated LFTs (2x upper limit of normal) - thrombocytopenia < 100-150k - renal dysfunction
49
What must be done prior to a speculum exam in the case of vaginal bleeding in the second half of pregnancy?
An ultrasound should be obtained prior to speculum exam to confirm the location of the placenta Manipulation of a placenta previa can cause catastrophic hemorrhage
50
What are the 3 main causes of vaginal bleeding in the second half of pregnancy
Placental abruption Placenta previa Vasa previa
51
What are the main causes of postpartum hemorrhage?
Can be remembered by the 4 Ts mnemonic Tone (uterine atony) Trauma (laceration, rupture) Tissue (retained products of conception, blood clots, placenta accreta/percreta) Thrombin (coagulopathy)
52
What anatomical landmark represents 0 station during delivery? +3 station?
0 station is at the ischial spines +3 station is at the vaginal introitus
53
What differentiates true labor from false labor?
True labor has contractions that produce cervical change False labor (braxton-hicks contractions) produce no cervical change
54
What are indicators of fetal distress on fetal monitoring
Fetal bradycardia Late deceleration (drops in FHR during and more than 30 seconds after a contraction)
55
What position should a pregnant woman be positioned in during resuscitation?
Left lateral decubitus This position enhances venous return from the gravid uterus
56
What are common steps to relieve shoulder dystocia?
McRobers maneuver (hyperflexion of the hip and keeping knees apart) Suprapubic pressure (immediately above pubic symphysis, not at fundus) Corkscrew maneuver (pressure on anterior aspect of presenting shoulder to provider rotary motion) Gaskin maneuver (move patient to all fours position and provide gentle downward traction of infant head) Zavanelli maneuver (replace fetal head back into pelvis and transfer to OR for emergent cesarean)