Cryptococcus Flashcards
(28 cards)
The only specie proven pathogenic
Cryptococcus neoformans
C. neoformans causes
Cryptococcosis
Infection occurs in
Humans, Dogs, Cats, Cattle, Horses, Deer, Marine mammals, wild animals
Cryptococcosis is
A chronic mycotic infection involving respiratory tract, CNS
They reproduce by
Budding
In tissues and exudates, C. neoformans are surrounded by?
Prominent mucopolysacchardie capsule
C. neoformans contains capsule and is demonstrated by:
India ink in CSF or exudate
Also stained by:
Mucicarmine and Periodic Acid-Schiff
C. albicans grows on what media
Sabouraud agar
Colonies of C. neoformans are
Smooth, mucoid, and cream colored. Tan or brown with age
T/F: C. neoformans are urease positive
True
Major antigen
Capsular ppolysaccharide
Capsule contains:
Glucuronoxylomannan
Antigens are used in
Latex agglutination tests, ELISA, vaccination researches
Natural habitat of C. neoformans
Soil contaminated with pigeon excreta
Other reservoir of C. neoformans
Eucalyptus trees, decaying wood, fruit and vegetables
Transmission
Inhalation of aerosolized yeast cells or basidiospores
Dissemination occurs via:
Bloodstream and lymphatics
Predisposing factors
Immunosuppression (FeLV and FIV)
The most commonly affected specie of Cryptococcus neoformans
Cats
Forms of the disease (cryptococcosis) in cats
Nasal, Cutaneous, and Systemic
Forms of the disease in dogs
Pulmonary, CNS, and Ocular
Cyptococcosis is rare in what animal
Horse
This animal be a carrier but the disease is very rare
Birds
