Cushing's vs Addison's Flashcards
Which One?
Overproduction of ACTH thus releasing too much glucocorticoids.
Cushing’s - remember with Cushing’s hormones are High so they are CUSHioned
Which One?
Insufficient ACTH, and/or cortisol, aldosterone and androgens
Addison’s - remember with Addison’s cortisol is low so we need to ADD them
Most common cause: STOPPING long term use of corticosteroids
Addison’s
can be caused by abruptly stopping _____
Can be caused by long term use of corticosteroids
Cushing’s
long term use of?
Which One
Buffalo hum, mid section obesity with skinny arms and legs
Cushing’s
physical changes
Which One?
Hyperglycemia
Cushing’s
sugar
Bruise easily
Cushing’s
blood vessels
striae
Cushing’s
skin
osteoporosis and muscle wasting
Cushing’s
bones and muscles
moon face
Cushing’s-
facial changes
HTN
Cushing’s
Heart Failure
Cushing’s
hair growth effected
Cushing’s
menses eases and most common age for women is 20-40
Cushing’s
INCREASED Sodium
Cushing’s
DECREASED Potassium
Cushing’s
Treatment is Mitotane
Cushing’s
muscle weakness, anorexia and fatigue
Addison’s,
general symptoms
bronze/dark pigmentations of mucous membranes and skin
Addison’s-
skin changes
DECREASED sodium
Addison’s
sodium
DECREASED glucose
Addison’s
glucose
INCREASED Potassium
Addison’s
K+
postural hypotension
Addison’s
BP
cyanosis, vascular collapse, renal shutdown, extreme dehydration and systemic shock
Addison’s Crisis -
Emergency - s/s