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Flashcards in Cushings Deck (9)
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1

Define cushings

Associated with excess cortisol production

2

Pathophysiology of pituitary dependant form

Benign tumour of gland results in excessive adrenocorticotrphic hormone production
Leads to increased cortisol production

3

Pathophysiology of adrenal dependant form

Associated with functional adenomas or adenocarcinomas of adrenal gland
Results in excessive cortisol production

4

What condition may be secondary to cushings and why

D.mellitus

Cortisol regulates glucose metabolism during stressful periods
Excessive hormone production leads to hyperglycaemia

5

Which is the most common form

Pituitary dependant

6

Who is most affected

Middle age dogs

7

Risk factors (2)

Excessive admin of corticosteroids
Prolonged high stress

8

Clinical signs (8)

PUPD
Involuntary night urination
Increased hunger
Obesity
Distended abdomen
Skin hyperpigmentation
Flank alopecia

9

Diagnosis (5)

Hx/cs/exam
Low/high DDST
ACTH stim
Abdominal ultrasound (adrenal)
MRI/CT of pituitary