Cushings Flashcards
(9 cards)
1
Q
Define cushings
A
Associated with excess cortisol production
2
Q
Pathophysiology of pituitary dependant form
A
Benign tumour of gland results in excessive adrenocorticotrphic hormone production
Leads to increased cortisol production
3
Q
Pathophysiology of adrenal dependant form
A
Associated with functional adenomas or adenocarcinomas of adrenal gland
Results in excessive cortisol production
4
Q
What condition may be secondary to cushings and why
A
D.mellitus
Cortisol regulates glucose metabolism during stressful periods
Excessive hormone production leads to hyperglycaemia
5
Q
Which is the most common form
A
Pituitary dependant
6
Q
Who is most affected
A
Middle age dogs
7
Q
Risk factors (2)
A
Excessive admin of corticosteroids
Prolonged high stress
8
Q
Clinical signs (8)
A
PUPD Involuntary night urination Increased hunger Obesity Distended abdomen Skin hyperpigmentation Flank alopecia
9
Q
Diagnosis (5)
A
Hx/cs/exam Low/high DDST ACTH stim Abdominal ultrasound (adrenal) MRI/CT of pituitary
