CV Meds Flashcards

1
Q

Labetalol Dose + Trade Name

A

IVP: 5mg q10min Max 20mg
Gtt: 0.05mg/kg/min

Trandate

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2
Q

Labetalol MOA

A

Selective alpha 1
Nonselective beta 1,2
Beta:alpha = 7:1

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3
Q

Labetalol Onset & Duration

A

O: 2-5min
D: 45min

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4
Q

Esmolol Dose + Trade Name

A

IVP: 10mg q5min
Induction: 30-50mg
Gtt: 50-250mcg/kg/min

Brevibloc

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5
Q

Esmolol MOA

A

Selective Beta 1 blocker

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6
Q

Esmolol Onset + Duration

A

O: 1-2min
D: 10min

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7
Q

Metoprolol Dose + Trade Name

A

1-5mg q5min

Blocks of 5 mg

Lopressor/Toprol

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8
Q

Metoprolol MOA

A

Selective Beta 1 blocker

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9
Q

Metoprolol Onset + Duration

A

O: <5min
D: 5-8hrs

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10
Q

Hydralazine Dose + Trade Name

A

2.5-5mg q15min (Max 15mg)
or 0.1-0.2mg/kg

Apresoline

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11
Q

Hydralazine MOA

A

Direct, Arteriolar vasodilator
GC -> cGMP
Decrease ITP and Ca release

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12
Q

Hydralazine Onset + Duration

A

O: 10-20min
D: 3-6hrs

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13
Q

Nitroglycerine Dose + Trade Name

A

0.2-1.5mcg/kg/min
or
5-10mcg/min

Nitrostat

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14
Q

Nitroglycerine MOA

A

Venous vasodilator

NO donor -> cGMP –> inhibits calcium entry into smooth muscle and increases uptake by endoplasmic reticulum

Decrease preload

Acts on venous capacitance vessels and large coronary arteries

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15
Q

Nicardipine Dose + Trade Name

A

Gtt: 5-15mg/hr

Cardene

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16
Q

Nicardipine MOA

A

Dihydropyridine Ca channel blocker
Modulation of L Type VG Ca channels
Decrease calcium influx…inhibits excitation-contraction coupling

Selective for arteriolar beds

17
Q

Ephedrine Dose

A

5-10mg
Max: 150mg in 24hr

18
Q

Ephedrine MOA

A

Indirect - causes release of NE from
postganglionic sympathetic nerve endings

Alpha/Beta agonist

19
Q

Phenylephrine Dose + Trade Name

A

50-100mcg

Neosynephrine

20
Q

Phenylephrine MOA

A

Selective alpha1 agonist
A little bit: Indirect - release of NE

Concern: Reflex Bradycardia

21
Q

Vasopressin Dose

A

1-2 units
Gtt: 1-6units/hr

22
Q

Vasopressin MOA

A

ADH - acts on V1 receptor Arterial constriction

Increases H2O reabsorption kidneys (V2) via increasing renal-collecting duct permeability

23
Q

Norepi Dose

A

IVP: 5-10mcg
Gtt: 0.01-1mcg/kg/min
or 1-5mcg/kg

24
Q

Norepi MOA

A

Alpha 1 > Beta 1 > Beta 2

25
Q

Epi Dose

A

IVP: 5-10mcg
Gtt: 0.01-1mcg/kg/min
or 1-5mcg/min

Infusion for receptors
1-2 mcg/min: beta-2
4 mcg/min: beta-1
10-20 mcg/min: Predominately alpha

26
Q

Epi MOA

A

Beta 2 > Beta 1 > Alpha 2 > Alpha 1