CV System- Adverse Effects/Interactions Flashcards by Zoe Lyon

Q

Loop diuretics

A

Nausea, dizziness

NSAIDs, ACE inhibitors

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Q

Thiazides

A

Electrolyte imbalance, exacerbation or precipitation of gout

NSAIDs, digoxin

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Q

Potassium-sparing diuretics

A

Gastrointestinal

NSAIDs, ACE inhibitors

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Q

Osmotic diuretics

A

Hypotension

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Q

Carbonic anhydrase inhibitors

A

Parasthesia

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Q

ACE inhibitors

A

Cough, hyperkalemia

Lithium, NSAIDs

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Q

ARBs

A

Hypotension, fatigue

Diuretics

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Q

Neprilysin inhibitors

A

Hypokalemia, hypoglycemia

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Q

Beta blockers

A

Bradycardia, bronchospasm

NSAIDs, digoxin

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Q

Alpha blockers

A

Dizziness, headache

Hypotensive drugs

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Q

Calcium channel blockers

A

Ankle swelling, oedema

Beta blockers, digoxin

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Q

Nitrates

A

Hypotension, headache

Antihypertensives

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Q

Sympathomimetics

A

Arrhythmia

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Q

Antiplatelets

A

GI irritation and bleeding

Anticoagulants

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Q

Coumarin

A

Abnormal bleeding

NSAIDs, diuretics (multiple drug interactions)

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Q

Direct Factor Xa inhibitors

A

Abnormal bleeding

Q

Heparins

A

Abnormal bleeding

Q

HMG-CoA reductase inhibitors

A

Myalgia

Verapamil, macrolides

Q

Class I anti-arrhythmics

A

Oedema

Q

Class II anti-arrhythmics

A

Hypotension

Q

Class III anti-arrhythmics

A

Nausea and vomiting

Q

Class IV anti-arrhythmics

A

Hypotension (verapamil)

Constipation (diltiazem)

Q

Cardiac glycosides

A

Fatigue, nausea

Q

Adenosine

A

Nausea

Contraindicated in obstructive airway disease

Antimuscarinic/anticholinergic

Urinary retention

Magnesium

Electrolyte irregularities

Direct renin inhibitor

Diarrhoea, cough

Alpha-2-adrenergic agonist

Constipation, dry mouth

Selective I(f) current inhibitors

Bradycardia

Anticoagulants - direct thrombin inhibitor

Abnormal bleeding, bruising

Thrombolytics/fibrinolytics

Haemorrhage, ecchymosis, hypotension