Infections-MoA

Question 1

Beta lactams (penicillins, carbapenems, cephalosporins)

Answer 1

Inhibition of bacterial cell wall synthesis

Question 2

Trimethoprim

Answer 2

Inhibition of dihydrofolate reductase

Question 3

Ciprofloxacin

Answer 3

Inhibition of bacterial DNA gyrase

Question 4

Erythromycin, azithromycin

Answer 4

Inhibition of bacterial protein synthesis

Question 5

Doxycycline, tetracycline

Answer 5

Inhibition of bacterial protein synthesis

Question 6

Nitrofurantoin

Answer 6

Bacterial DNA interference

Question 7

Gentamicin

Answer 7

Inhibition of bacterial protein synthesis

Question 8

Vancomycin

Answer 8

Inhibition of cell wall synthesis in Gram-positive bacteria

Question 9

Metronidazole

Answer 9

Inhibition of bacterial DNA synthesis

Question 10

Isoniazid, ethambutol

Answer 10

Inhibition of mycobacterial cell wall synthesis

Question 11

Rifampicin

Answer 11

Inhibition of mycobacterial RNA synthesis

Question 12

Interferon alpha

Answer 12

Activation of antiviral intracellular and immune responses

Question 13

Aciclovir, ganciclovir

Answer 13

Virus replication blockade

Question 14

Oseltamivir

Answer 14

Prevention of viral budding and infectivity

Question 15

Ribavirin

Answer 15

Disrupts viral RNA synthesis

Question 16

Tenofovir

Answer 16

Blockade of viral reverse transcriptase function for viral genetic replication

Question 17

Lopinavir

Answer 17

Blockade of viral protease required for virus particle assembly

Question 18

Dolutegravir

Answer 18

Disrupts integration of HIV genome into host chromosomes

Question 19

Enfuvirtide

Answer 19

Blockade of virus fusion to target cell membrane

Question 20

Maraviroc

Answer 20

Blockade of HIV binding to co-factor for cell entry

Question 21

Triazole anti-fungal agent

Answer 21

Disruption of fungal membrane function

Question 22

Clindamycin

Answer 22

Inhibition of bacterial protein synthesis

Question 23

Gentamicin

Answer 23

Inhibition of bacterial protein synthesis

Question 24

Reverse transcriptase inhibitors

Answer 24

Blockade of viral reverse transcriptase function for viral genetic replication

Question 25

Ritonavir

Answer 25

Blockade of viral protease required for virus particle assembly

Question 26

Mebendazole

Answer 26

Disruption of microtubule assembly in helminth cells

Question 27

Permethrin

Answer 27

Inhibits invertebrate neural sodium channels, causing paralysis of pests

Question 28

Nevirapine

Answer 28

Blockade of viral reverse transcriptase function for viral genetic replication