CVD Flashcards
(36 cards)
Also known as CORONARY HEART DISEASE, ISCHEMIC HEART DISEASE, MYOCARDIAL ISCHEMIA, HEART DISEASE
Coronary Artery Disease
It is the most common and prevailing CVD in the world
Coronary Artery Disease
Is a condition in which there is an inadequate supply of blood and oxygen to the myocardium
CAD
What is the goal treatment of CAD
Alter the atherosclerotic progression
myocardial ___ is the amount of oxygen that the heart requires to function
demand
Amount of oxygen provided to the heart by coronary arteries
Myocardial supply
What are the non-modifiable risk factors of CAD
•Hereditary
•Genetics
•Gender: male>female until menopause, then equal risk
•Ethnic background: African Americans
•Age
What are the modifiable risk factors of CAD?
•Hyperlipidemia
•Hypercholesterolemia
•Total serum cholesterol above 300 mg/dL
•Increased LDL and Decreased HDL
•Cigarrette smoking
•Substance abuse
•Stress
•HTN
•Diabetes
Is a progressive disease ,characterized by the accumulation of the lipids and fibrous elements in the arterial blood vessel walls, which reduces blood flow to the myocardium.
Coronary Atherosclerosis/Atherosclerosis
Gradually increase in size and may partially occlude the vessel lumina, thus limiting coronary flow and causing ischemia especially during exercise.
Stable Plaques
Prone to ulceration or rupture even if there has been no significant impairment of coronary blood flow before the event.
Unstable plaques
What formation can suddenly cut off blood supply to the heart muscle, resulting in acute myocardial ischemia.
Thrombus formation
Smooth muscles proliferate and form a fibrous cap, which filled with lipid and inflammatory deposits called ____ or plaques.
Atheroma
Intracellular lipid content of macrophages exceeds their capacity to maintain lipid homeostasis
FOAM cells
The first visible sign of atherosclerosis
Yellow streak or patch of dead foam cells at the site of endothelial damage.
True or False:
Myocardial ischemia develops if the supply of coronary blood cannot meet the demand of the myocardium for oxygen and nutrients.
True
What are the common causes of increased myocardial demand for blood?
*Tachycardia
*Exercise
*Hypertension (Hypertrophy)
*Valvular disease
Myocardial cells become ischemic within ___ of coronary occlusion
10 seconds
What is the medical term for Chest Pain?
Angina
What is DVT
Deep Vein Thrombosis
It is the most common syptom associated with CAD
Chest Pain
A clinical syndrome that results from myocardial ischemia caused by inadequate myocardial blood and oxygen supply or an imbalance between oxygen supply and demand.
Angina Pectoris
In Angina Pectoris, the pain is caused by ______ that irritates myocardial nerve fibers
The buildup of lactic acid or abnormal stretching of the ischemic myocardium
It’s a normal way your body fuels your muscles when oxygen is in short supply.
Lactic Acid buildup