CVD Flashcards

(36 cards)

1
Q

Also known as CORONARY HEART DISEASE, ISCHEMIC HEART DISEASE, MYOCARDIAL ISCHEMIA, HEART DISEASE

A

Coronary Artery Disease

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2
Q

It is the most common and prevailing CVD in the world

A

Coronary Artery Disease

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3
Q

Is a condition in which there is an inadequate supply of blood and oxygen to the myocardium

A

CAD

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4
Q

What is the goal treatment of CAD

A

Alter the atherosclerotic progression

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5
Q

myocardial ___ is the amount of oxygen that the heart requires to function

A

demand

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6
Q

Amount of oxygen provided to the heart by coronary arteries

A

Myocardial supply

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7
Q

What are the non-modifiable risk factors of CAD

A

•Hereditary
•Genetics
•Gender: male>female until menopause, then equal risk
•Ethnic background: African Americans
•Age

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8
Q

What are the modifiable risk factors of CAD?

A

•Hyperlipidemia
•Hypercholesterolemia
•Total serum cholesterol above 300 mg/dL
•Increased LDL and Decreased HDL
•Cigarrette smoking
•Substance abuse
•Stress
•HTN
•Diabetes

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9
Q

Is a progressive disease ,characterized by the accumulation of the lipids and fibrous elements in the arterial blood vessel walls, which reduces blood flow to the myocardium.

A

Coronary Atherosclerosis/Atherosclerosis

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10
Q

Gradually increase in size and may partially occlude the vessel lumina, thus limiting coronary flow and causing ischemia especially during exercise.

A

Stable Plaques

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11
Q

Prone to ulceration or rupture even if there has been no significant impairment of coronary blood flow before the event.

A

Unstable plaques

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12
Q

What formation can suddenly cut off blood supply to the heart muscle, resulting in acute myocardial ischemia.

A

Thrombus formation

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13
Q

Smooth muscles proliferate and form a fibrous cap, which filled with lipid and inflammatory deposits called ____ or plaques.

A

Atheroma

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14
Q

Intracellular lipid content of macrophages exceeds their capacity to maintain lipid homeostasis

A

FOAM cells

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15
Q

The first visible sign of atherosclerosis

A

Yellow streak or patch of dead foam cells at the site of endothelial damage.

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16
Q

True or False:

Myocardial ischemia develops if the supply of coronary blood cannot meet the demand of the myocardium for oxygen and nutrients.

17
Q

What are the common causes of increased myocardial demand for blood?

A

*Tachycardia
*Exercise
*Hypertension (Hypertrophy)
*Valvular disease

18
Q

Myocardial cells become ischemic within ___ of coronary occlusion

19
Q

What is the medical term for Chest Pain?

20
Q

What is DVT

A

Deep Vein Thrombosis

21
Q

It is the most common syptom associated with CAD

22
Q

A clinical syndrome that results from myocardial ischemia caused by inadequate myocardial blood and oxygen supply or an imbalance between oxygen supply and demand.

A

Angina Pectoris

23
Q

In Angina Pectoris, the pain is caused by ______ that irritates myocardial nerve fibers

A

The buildup of lactic acid or abnormal stretching of the ischemic myocardium

24
Q

It’s a normal way your body fuels your muscles when oxygen is in short supply.

A

Lactic Acid buildup

25
Is produced when oxygen levels become low in cells within the areas of the body where metabolism takes place or in response to sympathetic overactivity related to epinephrine-type substances or exercise.
Lactic Acid
26
Also called exertional angina
Stable angina
27
Usually has a stable pattern of onset, duration, severity, and relieving factors
Stable angina
28
Also called preinfarction angina - associated with acute coronary insufficiency
Unstable angina
29
Occurs in an unpredictable degree or exertion or emotion and increases in occurrence, duration, and severity in time -- last longer than 15 mins.
Unstable angina
30
Symptoms of worsening cardiac ischemia - not relieved with nitroglycerin.
Unstable angina
31
What are the patterns of Angina?
•Variant angina •Silent ischemia •Intractable ischemia
32
Patterns of angina: Also called Prinzmetal's orvasospastic angina, results from coronary artery spasm and almost exclusively occurs at rest.
Variant angina
33
Patterns of Angina: Objective evidence of ischemia (as evidenced by ECG changes during stress test) but patient reports no pain.
Silent ischemia
34
Patterns of Angina: Severe, incapacitating chest pain
Intractable angina
35
Patterns of angina: Also may occur in some individuals during mental stress and anger
Silent ischemia
36