Cytokine Inhibitors Flashcards

(5 cards)

1
Q

Categorisation

A
Jak inhibitors:
   Oclacitinib
   LOKIVETMEB
Cytokine gene expression inhibitors:
  Cyclosporine
  Tacrolimus
  Pimecrolimus
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2
Q

Cytokine gene expression inhibitors

Indications/Pharmacological effects

A

Inflammatory bowel disease (IBD)
Atopic Dermatitis
Keratoconjuctivitis
Autoimmune diseases

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3
Q

Jak inhibitors

Side effects

A

Vomiting/Diarrhea → Dehydration
Increased Blood Cholesterol
Suppresses hematopoesis
Allergic reaction(LOKIVETMEB→Rarely)

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4
Q

Jak inhibitors

Indications/Pharmacological effects

A

Anti inflammatory
Anti allergic
Puritus→itchy skin

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5
Q

Cytokine gene expression inhibitors

Side effects

A

Vomiting/Diarrhea → Dehydration
Gingival hyperplasia
Alopecia

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