D3.2 Inheritance (Analysis of patterns) Flashcards
Haemophilia
-sex linked
-recessive disorder
-clotting factor defeciency
Only _____ can be carriers for Haemophilia.
females
circles on pedigree chart are _____ while squares are _____.
females, males
Recessive disorders become more common with _____________________________. More likely that each individual is __________________.
interbreeding between close family members, carrying the recessive allele.
Discrete variation
-single gene
-distinct categories
-no environmental influence
-ex. blood type
Continuous variation
-many genes (polygenic)
-no distinct categories (many phenotypes)
-environmental influence
-ex. skin color
Mathematically determine outliers
unlinked genes
genes found on separate chromosomes
segregation
separation of alleles during meiosis
independent assortment
segregation of alleles in a way that the inheritance of one doesn’t influence the other
independent assortment is ___________________.
related to random orientation
Dihybrid cross
predict outcomes of 2 unlinked autosomal genes
How to do a dihybrid cross?
-list parents’ genotypes (HhRr * HhRr)
-do FOIL to find gametes (HR, Hr, hR, hr)
-put each of these on the top/sides of the four columns
-fill in (there should be 4 letters in each box)
phenotypic ratio
All of the phenotypes in a dihybrid cross represented as a ratio (ex. 9:3:3:1)
locus
specific location of gene on a chromosome
linked genes
genes located on the same chromosome
Linked genes are inherited together unless ______________________. Genes closer together are _____.
recombination occurs during prophase I. (crossing over), more likely to be inherited
Unlinked gene notation (_____)
RrGg
Recombinant
new combination of alleles on chromosome as a result of crossing over in prophase 1
If my gametes are RG and rg, then my recombinants are ____________.
Rg and rG
we can use chi-squared test to determine _______
if our observed data is different than our expected data.
hypothesis
there is a significant difference between what we observed and what we expected