Datos / HLAs Flashcards

1
Q

Enfermedades Relacionadas a HLA-B27

A

Espondilitis Anquilosante
Artitis Reactiva ( Reiter )
Artritis Psoriasica
Artritis Enteropática ( Cuci o Crohn )

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2
Q

HLA presentes en Lupus

A

HLA-DR2 y DR3

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3
Q

HLA presentes en Enfermedad Celiaca

A

HLA DQ2 y DQ8

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4
Q

Genes presentes en Artitis Reumatoide

A

HLA-DR4 y HLA-DR1 ( Lupus en medio de AR )

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5
Q

¿ Anticuerpo más sensible en LES ?

A

ANAa = antinucleares en un 93% de Sensibilidad

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6
Q

¿ Anticuerpo más especifico en LES ?

A

Anti-Smith en un 97% de especificidad

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7
Q

¿ Anticuerpo predictor de actividad renal en LES ?

A

Anti- dsDNA (+) 95% de Especificidad

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8
Q

¿ Anticuerpo asociado a lupus-like inducido por fármacos ?

A

Anticuerpo anti-histona

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9
Q

¿ Anticuerpo asociado a Lupus Neonatal ?

A

Anti-ro

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10
Q

¿ Anticuerpo asociado a psicosis y depresión en LES ?

A

Ac anti-ribosomal

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11
Q

Enfermedad asociada a Anti-scl 70

A

Esclerosis Sistémica

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12
Q

Enfermedad asociada a Ac antimembrana basal

A

Sindrome de Goodpasture

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13
Q

Anticuerpo positivo en Wegener

A

C-ANCA

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14
Q

Anticuerpo positivo en Churg-Strauss

A

P-ANCA

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15
Q

Contra qué va dirigido especificamente C-ANCA

A

Contra proteinasa - 3

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16
Q

¿ Contra qué va dirigido P-ANCA ?

A

Contra Mieloperoxidasa